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Biomedical subjects

H M Bhatia

Publications and source records attributed to H M Bhatia.

At least 37 records · Page 2Linked to original sources
PubMed1985

Quantitation of antibody uptake on A group erythrocytes using immunoautoradiography and monoclonal IgM anti-A.

The number of antibody molecules on individual erythrocytes was counted in A1, A2, A3 B and A group individuals using immunoautoradiography (IAR) and monoclonal IgM anti-A1. Quantitation was also done for A group pregnant women. The number of antibody molecules on different red cells of an individual varied widely. Gross variations were also noted in cells of different individuals from one and the same group. The mean values of the uptake of the number of antibody molecules showed the following range A1 greater than A2 greater than Ax greater than A3B. When compared to the average for total A1 adults, red cells of pregnant women and newborn infants showed a 10.7% and 19.7% reduction respectively, in antibody uptake. The mean number of antibody molecules per A1 adult red cells was 5.6 +/- 3 X 10(4), while A2 had 0.85 +/- 0.35 X 10(4) molecules, thus showing a significant quantitative variation.

ABO Blood-Group System↗
PubMed1984

I-i- phenotype in a large kindred Indian family.

The I-i- phenotype was found to be a familial character up to three generations in a large Indian family having 93 members. 15 members showed highly depressed Ii antigens while 6 of the members had partial depression of the Ii antigens on their red cells. It was evident in the family that the phenotype is associated with A1 antigen. The A1 antigen score on the red cells was significantly higher among the subjects with depressed Ii antigens. The I-i- status was not considered as a dominant or a recessive character nor does the partial depression of the Ii antigens indicate a heterozygous state of the variant gene.

ABO Blood-Group System↗