Biomedical subjects
Publications and source records attributed to H Lumerman.
A patient with Munchausen's syndrome received treatment from at least 25 dental practitioners in the New York metropolitan area. The patient and the syndrome are described to alert the dental community about this patient who is still presumed to be living in the New York area.
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A case of gingival hyperplasia associated with the administration of nifedipine is reported. Clinically and histologically, the tissue resembled that seen in hyperplasia induced by phenytoin (Dilantin). We believe this to be the first reported case of gingival hyperplasia associated with this drug.
A case of proliferative myositis of the masseter muscle in a 62-year-old woman is presented and pertinent literature is reviewed. This benign pseudosarcomatous proliferative lesion has not been previously reported in any of the muscles of mastication. Clinically the patient presented with pain and difficulty in opening of the mouth. On initial examination, a malignant salivary gland tumor was suspected. The proliferative myositis exhibits a disturbing microscopic appearance characterized by the presence of numerous hyperchromatic fibroblasts and oval or spindle-shaped giant cells which resemble malignant rhabdomyoblasts. These lesions have been often misdiagnosed as rhabdomyosarcoma and other types of sarcomas. Awareness of the microscopic characteristics of proliferative myositis and the possibility of its occurrence in the perioral soft tissues is important in avoiding misdiagnosis of this benign condition.
In an attempt to define more accurately the tumors grouped under the heading of "adenocarcinoma of salivary gland origin," we reviewed the cases in our registry that were classified as adenocarcinoma, carcinoma of salivary gland origin, and infiltrating epithelial salivary gland tumors. Eleven tumors that had certain unique microscopic features in common were identified. These eleven tumors and one that was reviewed in consultation make up the basis of this study. We classified these lesions as lobular carcinoma of salivary gland origin because of their remarkable microscopic resemblance to the breast tumors of the same name. These lesions appear to be of low-grade malignancy and have not recurred or metastasized in any of the eleven cases for which we have follow-up data, at times ranging from 5 to 80 months.
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Four cases of an unusual skin eruption related to mandibular block injection are presented. The authors suggest an immunologic basis for the reaction, probably to the methylparaben preseravtive, and discuss a possible pathogenic mechanism. The medical-dental literature concerning untoward reactions to lidocaine is reviewed; particular attention is given alleged allergic reactions.
The keratoacanthoma is a tumorlike proliferation which is rarely seen in the oral cavity. Both clinically and microscopically, it may bear close resemblance to squamous-cell carcinoma. The following article discusses the keratoacanthoma and, in addition, presents a case report of solitary intraoral keratoacanthoma.
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Two previously unreported cases of sialadenoma papilliferum are presented. This brings the total number of reported cases of this entity to five. A review of the literature and a discussion of the histopathologic characteristics and possible histogenesis of the sialadenoma papilliferum are included.
This article reviews the literature of the papillary cystadenoma of minor salivary gland origin and discusses and attempts to clarify the true nature of these lesions. The criteria for diagnosis are presented, and classification of this lesion based on the Histological Typing of Salivary Gland Tumours (World Health Organization) is suggested. In addition, an interesting variant, which we have called the papillary cystadenoma, mucous-cell type, is presented.
Desmoplastic fibroma (fibromatosis) is rarely seen as a primary tumor of bone. Its occurrence as a central lesion in the jaws is even more uncommon. The case of a 26-year-old woman with a central desmoplastic fibroma of the body of the mandible is described. The lesion manifested as a painless swelling and radiographically appeared as a well-delineated radiolucency. On exploration, the tumor was found to have infiltrated through the lingual cortex. Microscopic examination revealed invasion of muscle. The clinicopathologic features of this case and of the twenty-five similar lesions previously described in the literature are analyzed and discussed.
A case of keratoacanthoma of the maxillary gingiva in a 12-year-old white boy has been presented. This is only the fourth case of solitary intraoral keratoacanthoma reported in the English-language literature. A review of the literature on solitary and multiple mucosal keratoacanthomas and the incidence of ectopic sebaceous glands has been included. In all mucous membrane locations where keratoacanthomas have arisen, there have been other reported cases of ectopic sebaceous glands in these areas. These findings have led us to consider that intraoral and perhaps all mucous membrane keratoacanthomas arise i, sebaceous glands or their ducts, whether they be normal in their location, as in the buccal mucosa, or ectopic.
A case of a malignant mucoepidermoid tumor (poorly differentiated) occurring simultaneously with a homolateral Warthin's tumor is presented. The simultaneous occurrence of two salivary gland tumors of different types is extremely rare. Only five cases have been reported in the literature. The occurrence of a malignant mucoepidermoid tumor and a Warthin's tumor in the same patient has not been previously reported.
Six new cases of the calcifying odontogenic cyst are presented. These and sixty-four previously reported cases have been studied to further delineate characteristic clinical, radiographic, and histopathologic features of the calcifying odontogenic cyst. A review of the literature with emphasis on the possible histogenesis of the calcifying odontogenic cyst and the nature of the "ghost cells" and their products is also presented.
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