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Biomedical subjects

H Luckhaupt

Publications and source records attributed to H Luckhaupt.

46 records · Page 3Linked to original sources
PubMed1986

[Anaerobic infections in ulcerating tumors of the head and neck. A contribution to the problem of odors].

Incurable exulcerated head and neck tumours frequently produce a foul odour which is a great problem for patients, nurses and family of patients. This odour is a sign of anaerobic infection in necrotic tumours. Bacteriological examinations in fifteen patients with tumours of the oral cavity, the oropharynx and with recurrent tumours of the hypopharynx and larynx showed anaerobic bacteria. Bacteroides melaninogenicus, B. oralis, B. bivius, Peptococcus and Fusobacterium were most frequently represented. Five cases showed mixed aerobic-anaerobic infections. Foul odour disappeared regularly after a short time by antianaerobic chemotherapy (clindamycin or metronidazole). Foetor is evidently caused by microbial activity of anaerobic bacteria in secondary infected tumours. Antibiotic treatment directed strictly against anaerobes helps to improve quality of life of patients with advanced head and neck cancer with regard to foetor.

Bacteria, Anaerobic↗
PubMed1985

[Antibiotic therapy in patients with renal insufficiency].

For the otolaryngologist (ENT specialist), too, antibiotics are among the most frequently prescribed drugs. This article gives the essential fundamentals for the antibiotic treatment of patients with restricted kidney functions, as well as advice for antibiotic therapy in clinics and in medical practice.

Aminoglycosides↗
PubMed1985

[The use of antibiotics and chemotherapeutic agents during pregnancy].

Physicians engaged in all general and specialist fields of medicine may at times be confronted with the necessity of prescribing an antibiotic or chemotherapy for pregnant patients. This article gives ample advice on the therapy with antibiotics and chemotherapeutic agents during pregnancy.

Aminoglycosides↗
PubMed1985

[Tuberculosis of the cervical lymph nodes: report of 193 cases].

193 patients suffering from tuberculosis of the cervical lymph nodes are analysed. All cases were examined with respect to sex, age, nationality and typical findings of blood parameters. The diagnostic and therapeutic proceedings are elucidated. Histological diagnosis should be done, but micro-biology is only significant in a few cases. Tuberculosis of lymph nodes of neck should be considered in obscure swellings of the neck.

Adolescent↗
PubMed1985

[Significance and problems of pseudomonas infection in ENT medicine].

Pseudomonas aeruginosa is frequently cultured in chronic otitis media, in external otitis, and from infected radical mastoid cavities. Necrotizing external otitis is a typical infection caused by Pseudomonas aeruginosa. Perichondritis of the external ear is sometimes due to a Pseudomonas aeruginosa infection. Some cases of chronic sinusitis and wound infections in patients with tracheostomy are caused by this organism. Antiseptic agents or astringents should be used for local treatment of Pseudomonas infected ears. If these fail local treatment with azlocillin for several days is a good alternative. Systemic antibiotic therapy is also available for Pseudomonas aeruginosa infections.

Anti-Bacterial Agents↗
PubMed1984

[Treatment and treatment results of Zenker's diverticulum].

A series of 51 patients is described who were treated surgically for a Zenker's diverticulum. The surgical techniques available and the results of treatment are discussed. This report emphasises the usefulness of the diverticulofixatio described by Koenig. This was especially useful in elderly patients in poor general condition.

Adult↗
PubMedDate not supplied

Concentrations of ampicillin and sulbactam in serum and tissues of patients undergoing ENT surgery.

2 g ampicillin and 1 g sulbactam were given by infusion to 24 patients who were to be operated on in the ENT region. About 1 hour later during the operation samples of serum and of various tissues were taken and analysed for ampicillin and sulbactam. The mean serum concentrations of ampicillin and sulbactam were 59.2 mg/l and 31.6 mg/l, respectively. At the same time the concentrations of the two drugs were usually lower in the tissues than in serum. About 1 hour after the infusion the mean tissue concentration of ampicillin was 33.5 mg/kg and of sulbactam 19.5 mg/kg. The results show that ampicillin and sulbactam penetrate within an hour into the different tissues affected by the operation and maintain about the same ratio as in serum (2:1). The concentrations of ampicillin and sulbactam measured in the different compartments are capable of inhibiting the bacteria most frequently involved in ENT infections. These measurements unequivocally support the use of the ampicillin/sulbactam combination in the treatment and perioperative prophylaxis of bacterial infections of the ENT tract.

Adolescent↗