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Biomedical subjects

H Loew

Publications and source records attributed to H Loew.

At least 37 records · Page 2Linked to original sources

Malignant nephrosclerosis during pregnancy and in the postpartum period (the uremic hemolytic syndrome).

Histologic, immunohistologic, and ultrastructural features are presented of two cases with malignant nephrosclerosis during pregnancy. Primary malignant nephrosclerosis emerges as a clinical entity which can be distinguished from toxemia of pregnancy in the midtrimester and post partum. The first description of malignant nephrosclerosis dates from 40 years ago, but only a few cases were reported associated with pregnancy. Although disseminated intravascular coagulation seems involved, the morphology is different from that of toxemia. Malignant nephrosclerosis reveals a close similarity to the hemolytic uremic syndrome. Early diagnosis by renal biopsy and proper treatment may prevent a lethal outcome due to progressive failure.

Adult↗

[Familial hemolytic anemia and terminal renal failure (author's transl)].

We report about a patient with corpuscular hemolytic anemia and chronic glomerulonephritis in the state of terminal renal failure. The hematocrit decreased to 11% gradually with the progression of uremia. The hematological studies revealed the typical signs of hemolytic anemia. We found a splenic destruction of 51-Cr labelled red cells combined with an extremely short red cell life of 7 days. After splenectomy hematocrit improved to 32%. A complete normalisation could not be expected because of the chronic renal failure leading to anemia itself.

Adult↗

[Pyelonephritis].

Chronic pyelonephritis is, by definition, a chronic interestial nephritis due to immediate or late effects of bacterial infection of the renal parenchyma. The main diagnostic criterion is recurrent or permanent bacteriuria. As a rule, bacteriuria follows as a secondary symptom a primary renal disturbance such as malformations of the urinary tract, stones, gout, analgesic abuse, diabetes mellitus or pregnancy. It is most important to eradicate predisposing factors, if possible, for successful antimicrobial therapy. In some cases, permanent intensive chemotherapy might be more harmful to the patient than untreated chronic bacteriuria, in itself.

Bacteriuria↗