Search PubMed⌕ Search

Biomedical subjects

H Lindholm

Publications and source records attributed to H Lindholm.

At least 37 records · Page 2Linked to original sources
PubMed1995

Cardiovascular functional disorder and stress among patients having neck-shoulder symptoms.

OBJECTIVES: To investigate if autonomic nervous system function, reflected in cardiovascular variables, among patients with neck-shoulder symptoms (tension neck group (T)) differed from that in a symptom free control group (C), and to establish its relation with pain and psychological stress. METHODS: Twelve women with tension neck and nine controls in secretarial jobs were studied. They underwent an orthostatic test, deep breathing test, Valsalva manoeuvre, isometric handgrip test, and muscular endurance test. Pain was measured using visual analogue scales, and psychological stress by the Modified Somatic Perception Questionnaire (MSPQ). Plasma endothelin-1 (ET-1) was measured using high pressure liquid chromatography and radioimmunoassay. RESULTS: Signs of psychological stress were significantly (p < 0.001) more common in group T than in group C. Mean resting heart rate in group T (77.8 (SE 2.9) beats/min; range 64-100) was significantly greater than that in group C (63.8 (3.1) beats/min; range 52-80) (p < 0.01). In the orthostatic test, the overall changes in R-R intervals during the first 40 heart beats after standing up and during seven minutes of testing differed significantly between the groups (p < 0.001, < 0.05, respectively). The increase in diastolic blood pressure in the three minute isometric handgrip test was significantly less in group T (19.4 (3.5) mm Hg; range -5 to 35) than in group C (30 (3.4) mm Hg; range 15-50) (p < 0.05). The MSPQ score in the study group (n = 21) correlated positively with resting heart rate (r = 0.462, p < 0.05) and negatively with increase in diastolic blood pressure (r = -0.514, p < 0.05). Plasma concentrations of ET-1 did not differ between the groups. CONCLUSION: Increased sympathetic activity was found among patients having neck-shoulder symptoms. Local mechanisms may have influenced the cardiovascular changes observed during isometric testing in these patients.

Adult↗
PubMed1995

Neuropsychologic and cardiovascular effects of clemastine fumarate under pressure.

Allergic rhinitis and mild respiratory infections have been widely accepted as temporary contraindications for fitness to dive. Nonetheless, several sport and professional divers use antihistamines to ease ear, nose, and throat (ENT) problems, especially for opening tubal ostium. Some divers know they are unfit to dive, but for a variety of reasons (e.g., money or short holiday) they try to clear their ears. Thus, the use of antihistaminic drugs (like clemastine fumarate) is common during diving. This double-blind, crossover study indicates that this special antihistamine does not increase the sedative effects of nitrogen narcosis, nor does it increase the level of cardiac arrhythmias. Liberal use of antihistamines while diving cannot be recommended because of possible complications connected with different preparations and the temporary limitations they impose on the diver.

Adult↗
PubMed1994

Bilateral distal biceps tendon avulsions with use of anabolic steroids.

A case of a young body-builder who had ingested megadoses of anabolic-androgenic steroids (AAS) for 6 yr and who sustained bilateral avulsions of the distal biceps tendon is presented. Explosive behavior, painful gynecomastia, and a slight hypertrophy of both the left and right ventricular walls of the heart were other possible adverse effects of AAS in this patient. Reinsertion of both distal biceps tendons to the radial tuberosity was performed according to the Boyd-Anderson technique and a good result was achieved.

Adult↗
PubMed1992

Cardiovascular functional disorder in primary fibromyalgia: a noninvasive study in 17 young men.

Cardiovascular functional stability was studied in 17 young men (20-year-old conscripts) with the symptoms of primary fibromyalgia (PF). They were compared to 20 medical students of the same age. The subjects underwent an orthostatic test, deep breathing test, Valsalva maneuver, and a handgrip test. They were evaluated by an autoanamnestic questionnaire on vegetative symptoms and laboratory tests on blood chemistry. The heart rate of the PF group after 8 min of active standing was 32 +/- 15 beats/min greater than at supine rest. The corresponding figure for the controls was 23 +/- 7 beats/min (p = 0.001). Twelve conscripts with PF (71%) presented sympathicotonic cardiovascular reaction on the orthostatic test (p < 0.001). Four of these sympathicotonic conscripts and two other conscripts (total 35%) had an abnormal high index of dystonic symptoms (p = 0.01). The results suggest that young men with symptoms of PF have not only cardiovascular dystonic symptoms but also increased sympathetic nervous reactivity of the cardiovascular system.

Adolescent↗
PubMed1992

Prenatal diagnosis of distal arthrogryposis type I by ultrasonography.

Two consecutive pregnancies in a woman with initially undiagnosed type I distal arthrogryposis (DA) are reported. A prenatal diagnosis of the condition was made by ultrasound in the 17th week of gestation in one of the pregnancies, whereas in the subsequent pregnancy the disorder was excluded as early as 13 weeks' gestation. The diagnoses were verified at birth. The feasibility of prenatal diagnosis of DA type I in the second trimester is thus confirmed and its possibility in the late first trimester is suggested.

Adult↗
PubMed1991

Color Doppler studies in trophoblastic tumors: a preliminary report.

Ten women, referred because of a strong suspicion of gestational trophoblastic neoplasia, were examined by abdominal real-time ultrasound and color Doppler. The results were compared to those of pelvic angiography. In all but one case color Doppler examination revealed areas of increased vascularity. In all cases the findings of color Doppler and pelvic angiography agreed. Real-time ultrasound failed to detect abnormal uterine echoes in three of the patients where the other methods indicated tumor. The present study indicates that color Doppler could be of great value in a non-invasive assessment of trophoblastic tumors.

Journal Article↗
PubMed1991

Late complications after a Yersinia enterocolitica epidemic: a follow up study.

Ninety four Finnish conscripts were affected by a Yersinia enterocolitica epidemic in 1973. Thirteen years later 75 men completed a questionnaire about their present health. One half had no health problems, and the most common complaints in the other subjects were musculoskeletal disorders. Sixteen men wanted to be re-examined. In three cases a chronic connective tissue disease was diagnosed. Two men had ankylosing spondylitis. The most notable results of this study were (a) the fairly low number of late complications, (b) the close correlation between complications and the HLA-B27 antigen, and (c) the correlation between raised yersinia antibody titres and the late complications. The nature of the primary causative agent may affect the development of late complications.

Adult↗
PubMed1990

Prevalence of asthma in Finnish young men.

OBJECTIVE: To determine the prevalence of asthma in cohorts of Finnish young men in the period 1926-89. DESIGN: A retrospective analysis using reports and statistics of Finnish defence forces. SETTING: Call up examinations of candidates for military conscription and examination of conscripts discharged because of poor health. SUBJECTS: Roughly 900,000 men--that is, 98% of men of conscription age--examined in 1966-89 and a proportional but unknown number examined in 1926-61. MAIN OUTCOME MEASURES: Asthma recognised at call up examination, exemption from military service, and discharge from military service because of asthma. RESULTS: During 1926-61 the prevalence of asthma recorded at call up examinations remained steady at between 0.02% and 0.08%. Between 1961 and 1966, however, a continuous, linear rise began, the prevalence increasing from 0.29% in 1966 to 1.79% in 1989--that is, representing a sixfold increase. Compared with 1961 the rise was 20-fold. From 1966 to 1989 the sum of exemptions and discharges from military service due to asthma increased analogously sixfold. CONCLUSIONS: If the apparent increase in asthma detected in Finnish young men was due entirely to improved diagnostic methods and other confounding effects then some 95% of cases must have gone undiagnosed in the years before 1966. This seems inconceivable, which suggests that much of the increase was real. This conclusion is strengthened by the observed rise in exemptions and discharges due to asthma.

Adult↗
PubMed1988

Testicular hydrocele treated by bismuth phosphate injection.

Thirty-eight testicular hydroceles were treated by injection with 0.2-0.4 g of bismuth phosphate. The follow-up was completed in 32 cases, 17 (53%) of which showed complete regression although one patient had to wait 24 months for full regression. Eight patients (25%) showed clinical improvement and one patient (3%) had residual scrotal tenderness after otherwise successful treatment. Six patients (19%) did not improve and were treated surgically. The method may present an alternative to surgery in elderly patients with testicular hydrocele.

Aged↗
PubMed1984

Laryngeal edema as the only symptom of hypersensitivity to salicylic acid and other substances.

Idiosyncrasy to salicylic acid and related substances is well known, the most common symptoms being asthma, rhinorrhea and urticaria. We here describe two cases whose only symptoms were hoarseness and in which inspection revealed laryngeal edema when the patients ingested any of these substances. In cases of chronic recurring hoarseness, a history should be taken with respect to such hypersensitivity and suspect cases should be challenged, since a strict diet may improve the symptoms.

Adult↗
PubMed1984

Nephritis among young Finnish men.

During an eight-year period (1975-1982) 174 military conscripts (out of a total of 314,000) were submitted to Helsinki University Central Hospital, Fourth Department of Medicine, on suspicion of renal disease. Eighty-four had isolated hematuria, 61 hematuria and concomitant proteinuria and 29 persistent proteinuria. In 100 of them the urinary abnormality was an incidental finding, 62 suffered from symptoms of infection and the rest had other complaints. A renal biopsy was performed, yielding a representative sample in 171 cases, after other causes of the urinary abnormality had been excluded. Morphological analysis showed that 131 patients had glomerulonephritis, IgA nephropathy being the most common type (70 patients). Tubulo-interstitial nephritis was seen in two cases, and nephrocalcinosis in one. Among 37 cases with apparently normal glomeruli under light microscopy, immunofluorescence analysis revealed glomerular deposits other than IgA in 19 cases and no deposits in 15 (three were inadequate for this analysis). On the basis of the figures in this study the average number of annually detected cases of nephritis was 48 per 100,000 Finnish conscripts. During the same period an annual average of 46 per 100,000 young men were exempted from military service because of nephritis, giving an overall figure of 94 cases of nephritis detected annually per 100,000 young Finnish men.

Adult↗
PubMed1983

Sectorized psychiatry. A methodological study of the effects of reorganization on patients treated at a mental hospital.

The aim of the study was to find relevant methods and use them to investigate the effects of sectorized psychiatry on former mental hospital patients. Seventeen hypotheses were formulated, concerning both positive and negative effects of sectorized psychiatry. Relevance and expected availability decided the variables, which were based on information from medical registers, case records, death certificates, social authorities, courts of law, public health insurance, census office and personal interviews. The hypotheses were tested by the use of two groups of patients, 377 in one experimental group, and 377 in one control group. A matched control method was used. The study patients were domiciled in the catchment area for the first complete trial of sectorized psychiatric service in the Stockholm area. The control patients were domiciled in the catchment area for the remaining divisions of Beckomberga Mental Hospital. During the actual years, an experimental situation was at hand. Comparisons in each pair were performed, regarding the experimental year 1980. A methodological description of variables for measurement of the effects and changes in psychiatric care is presented. The comparison showed no significant differences in the analyses, regarding utilization of inpatient care at Beckomberga Hospital in 1980. Study patients had significantly more outpatient visits and day-care days compared to controls. Study patients reported significantly shorter time of public transportation between home and psychiatric service. Study patients were significantly more often discharged to the division's own agencies compared to controls. Study patients reported significantly less satisfaction with ward staff than controls. No significant differences in direct cost of treatment during the experimental year were registered. The conclusion is, that there are no consistent tendencies proving the new organization superior to the traditional one for these former mental hospital patients.

Adult↗
PubMed1978

Effects of perphenazine enanthate injections on prolactin levels in plasma from schizophrenic women and men.

Levels of prolactin (PRL) in plasma were determined in schizophrenic women and men after i.m. injections of 50-150 mg perphenazine enanthate (PE). In both sexes PRL levels increased dose-dependently. In men the effect was significant for 2 and in women for 9 days. Biperiden treatment did not influence the effect of PE on the PRL levels. The data support the view that clinically used doses of PE induce a small but significant blockade of central dopamine receptors.

Aged↗