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Biomedical subjects

H Levendoglu

Publications and source records attributed to H Levendoglu.

20 records · Page 2Linked to original sources

CT-guided percutaneous aspiration and catheter drainage of pyogenic liver abscesses.

Surgical drainage has been the accepted method of treatment for pyogenic liver abscesses. Modern imaging techniques have revolutionized the diagnosis and management of liver abscesses. Percutaneous aspiration and drainage have been reported as a treatment modality of pyogenic liver abscesses in the literature before. We treated 15 patients with pyogenic liver abscesses by percutaneous aspiration and drainage. All patients responded except two. No mortality was observed. Review of the literature and our experience with 15 patients suggest that because of the high recovery rate and few complications percutaneous aspiration and drainage should be the first line of treatment in the management of pyogenic liver abscesses.

Adult↗

A new PGE1 analogue (CL115,574) III. Effects on gastric acid and mucus secretion in man.

CL115,574, an analogue of PGE1, is a potent inhibitor of gastric acid secretion in animals. The effects of this compound on gastric acid and mucus secretion were studied in 8 male volunteers. The compound was well tolerated, and its maximally effective antisecretory dose (750 micrograms) inhibited pentagastrin stimulated acid secretion by approximately 40% over a 2-hour period, with stimulation beginning one hour after the drug was orally administered. CL115,574 proved to have a significant and sustained effect upon the stimulation of mucus secretion into gastric juice. Considering the possible role that mucus may play in mucosal cytoprotection, CL115,574 because of its antisecretory and mucogenic actions may prove to be an important clinical anti-ulcer compound.

Adult↗