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Biomedical subjects

H Le Brigand

Publications and source records attributed to H Le Brigand.

At least 19 recordsLinked to original sources

[Thymomas and associated diseases. Apropos of a series of 255 surgically treated thymomas].

The authors report on a series of 255 thymomas and the associated diseases most often auto-immune, myasthenia is the disease most frequently encountered (61% of cases). Next, but with a much reduced frequency of around 2%, come other diseases such as hypogammaglobulinaemia, erythroblastopenic anaemia, and disseminated lupus erythematosis. The authors analyse the effect of ablating the thymoma on the associated disease; those with myasthenia are the principal beneficiaries of thymic ablation, 83% in this series experiencing a good response. Besides myasthenia only erythroblastopenic anaemia obtained some benefit from thymic ablation; in all the other cases surgery to the thymic tumour had no benefit on the associated disease. In the light of their own experience the authors made a review of the literature of the different diseases associated with thymomas and made the point of the efficacy of thymectomy in the different diseases.

Agammaglobulinemia

[Mediastinal surgery in children].

From 96 surgical interventions in the child, the authors studied the repartition of tumours according to their histological nature, their benignity or malignancy. For each kind of tumour they gave its frequency and clinical, radiological and biological data. Above all they studied the distant results of these interventions with an important set back. The results are excellent for benign tumours and promising for malignant ones and enable the deduction of therapeutical indications.

Adolescent

[Profile of surgical tumors of the mediatinum. Apropos of a series of 742 operated patients].

The authors seek to draw statistical conclusions on the basis of 742 surgically treated mediastinal tumours. Tumours of the thymus were the most common (20%). They were followed by tumours of the thyroid, neurogenic tumours, haematosarcomas and mediastinal cysts - all with an occurrence rate of around 12 to 15%. From a histological standpoint, 34.5% of the tumours were malignant or "potentially malignant". After a topographical study of these tumours, the authors discuss the possibilities of surgical treatment, the latter being great even in the case of malignant lesions.

Humans

[Anatomo-clinical calssification of primary tumors of the pleura and possibility of their surgical treatment].

A distinction is drawn between first category includes peduncolates, giant seslocal and diffuse primary tumours of the pleura on anatomopathological grounds. The first category includes peduncolated, giant sessile, and "deceptive" forms; the latter those in which the lung is surrounded by a "pleural" and "serous" mantle. Treatment is discussed and the soundness of surgical management is stressed.

Diagnosis, Differential