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Biomedical subjects

H Laufman

Publications and source records attributed to H Laufman.

At least 37 records · Page 2Linked to original sources

Moist bacterial strike-through of surgical materials: confirmatory tests.

New tests consisting of modifications of the inverted Mason jar test confirm our previously reported studies which showed that woven and nonwoven surgical materials vary greatly in their ability to serve as barriers against moist bacterial strike-through. Among the woven materials, only tightly woven Pima cloth or materials treated with Quarpel waterproofing process or with polythene layer lamination was invariably resistant. However, tight-woven Pima cloth, which had been treated with Quarpel became permeable after 100 washing-sterilizing cycles. Of the nonwoven materials, single-layer nonwoven materials tended to unevenly permeable to moist bacterial strike-through. Only the front and sleeves of nonwoven gowns reinforced with polyethelene layer were invariably resistant to moist contamination.

Antisepsis↗

Immune response to L2 guinea pig leukemia-specific antigens.

Strain 2 guinea pigs were immunized with the LE-L2C cell line and challenged with either LE-L2C or BZ-L2C, a subline of L2C leukemia deficient in la gene product and C3 receptor. The LE-L2C-immune animals were completely protected from a challenge of 5 X 10(6) cells (100 times the lethal dose) of either cell line, and the delayed skin test responses for both lines of injected cells were equivalent. Thus established in vivo immune recognition of the leukemia antigen was similar for both cell lines. After repeated immunization of strain 2 animals with BZ-L2C cells, animals were challenged with 3 X 10(5) viable cells; 9 of 13 animals survived. A subsequent 5 x 10 (6) challenge lowered survival to 8 of the 13 animals. The skin test response to BZ-L2C developed slowly during the immunization period, but survivors of the viable cell challenge exhibited good responses to skin testing with BZ-L2C or LE-L2C leukemic cells. Thus the BZ-L2C cell line possesses a leukemia-specific antigen, but the immunogenicity of this mutant line is decreased when compared to that of the LE-L2C line.

Animals↗

Synthetic absorable sutures.

Based on the many reports published in the past several years, the synthetic absorbable sutures have been recognized as an important step forward in the history of suture materials. Synthetic absorbable sutures have been approved by the Food and Drug Administration for almost all surgical uses with the exception of certain cardiovascular and neurologic surgical procedures in which nonabsorbable sutures are mandatory, as, for example, in the suturing of a prosthesis to tissue. They have been used in many thousands of surgical operations of many types and show prospects of replacing other absorbable suture materials traditionally used in surgical operations. Moreover, because of their retained strength and low tissue reactivity, the synthetic absorbable materials are being used in some procedures in place of nonabsorbable materials. Thus, instead of using several different suture materials during some operations, the surgeon may find himself using one synthetic absorbable suture in different sizes for an entire procedure.

Abdomen↗

Use of disposable products in surgical practice.

Disposable products today are an important part of the multibillion dollar health devices industry. A few heavy-usage and low-usage examples of disposable products used by surgeons are chosen to demonstrate that in a 1,000-bed hospital, economy is rarely, if ever, a reason for converting from reusables to disposables. The actual reasons are more closely related to individual preference, availability, convenience, dependability, safely, and, in some cases, manufacturer's promotion. In a 24-hospital study of surgical apparel, it was found that only caps, masks, shoe covers, and other small items approached partly in cost between disposable and reusable items, where as the per-use cost of reusable larger items such as gowns and drapes was still much lower than that of their disposable counterparts. However, each hospital must make its own decisions based on all factors, not on economy alone.

Cellulose↗

Strike-through of moist contamination by woven and nonwoven surgical materials.

A test is described which correlates the stress of stretching surgical gown and drape material with moist bacterial strike-through. By application of this test to a number of woven and nonwoven surgical gown and drape materials, it was found that not all of these materials, either woven or nonwoven, are impermeable to moist contamination for equal periods of time. Nonwoven disposable materials now in use range from those which remain impermeable to moist bacterial permeation through all tests while some remain impermeable for limited periods of time, and others almost immediately permeable to moist bacterial penetration. The same situation holds for woven materials. Under conditions of our test, Quarpel treated Pima tight-woven cotton cloth was impermeable to moist bacterial strike-through, through up to 75 washing and sterilizing cyclings, while ordinary linen and untreated Pima cloth permitted bacterial permeation almost immediately. These results have significance in lengthy wet surgical operations.

Bacteria↗

Television in the operating room.

Television serves a number of useful purposes in the operating room. For the operating room supervisor, television surveillance provides an easy, economical method of keeping abreast of surgical and turnaround activities in each operating room. For the surgeon it provides an excellent vehicle for teaching, record keeping, remote viewing, and two way communication with the clinical pathology and x-ray departments, as well as with other consultants.

Education, Medical↗