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Biomedical subjects

H Lang

Publications and source records attributed to H Lang.

At least 235 records · Page 13Linked to original sources
PubMed1983

[Neuromyotonia].

Explore the source record for details and available documents.

Adolescent↗
PubMed1982

EMG dynamics in polymyositis. A quantitative single motor unit potential study.

A multidimensional quantitative EMG analysis method with averaged motor unit potentials (MUPs) was applied to a study of different stages of polymyositis. The duration parameters had a general tendency to increase in polymyositis. The only exception was the total MUP duration, which decreased in the onset stage of acute polymyositis. The amplitude tended to decrease in acute polymyositis but increase in chronic, progressive polymyositis. The number of fast components both in the whole MUP complex and in the main MUP tended to increase in all stages of polymyositis. The mean fast component duration in the main MUP tended to decrease in polymyositis. Satellites (small signals time-locked to the main component but part of it) were numerous in active stages of polymyositis. There were significant quantitative differences in most of the parameters in different stages of polymyositis.

Adolescent↗
PubMed1982

Macrophages as cytotoxic effector cells.

Cells of the mononuclear phagocyte system can be activated by lymphokines to both increased extracellular cytotoxicity against tumor targets and intracellular cytotoxicity against micro-organisms. In addition, these effector cells can kill antibody-coated target cells in an ADCC system. These two cytotoxic mechanisms can co-operate and act synergistically. Such an synergistic action is characterized by the specificity of the antibody which coats the target cells and not by the non-specific activation induced by high dosages of lymphokine. The lymphokine MCF has partially been purified and separated from a variety of other lymphokines. This purified material, when injected into mice intraperitoneally, activates the macrophages to strong cytotoxicity. Evidence obtained by the use of different rat anti-mouse macrophage monoclonal antibodies suggests that there exist different subpopulations of macrophage and that some of these subpopulations can be correlated to defined functions.

Animals↗
PubMed1981

[Differential diagnosis of acquired clubfoot (author's transl)].

The article introduces a patient of 14 years of age in whom clubfeet as well as paraspasticity had developed from his sixth year of life. Instead of the previously suspected heredodegenerative disease, a lipoma was found in the distal spinal canal which had prevented ascension of the spinal cord and had thus produced the described phenomenon.

Adolescent↗
PubMed1981

[Kidney involvement in "mixed connective tissue disease" (Sharp syndrome)].

The case in question of the Sharp-syndrome is a mixed collagenosis with symptoms of sclerodermia, Erythematodes visceralis, dermatomyositis and rheumatoid arthritis. Apart from the clinical symptomatology the immunological profile is decisive for the ascertainment of the diagnosis. With the help of 3 descriptions of cases is referred to a frequent participation of the kidneys, particularly histologically and immune-histologically. In contrast to the hitherto existing publications also in missing pathological findings of the urine a renal biopsy should be aspired to, since important therapeutic and prognostic considerations are dependent on this.

Adult↗
PubMed1980

[Mixed connective tissue disease (Sharp syndrome)].

In the Sharp syndrome we have to do with a mixed collagenosis with symptoms of sclerodermia, erythematodes visceralis, dermatomyositis and rheumatoid arthritis. Above all are observed a Raynaud syndrome, polyarthritis and polyarthralgias, swellings of hands and fingers and myositis and myalgia, respectively. For the ascertainment of the diagnosis as independent picture of a disease the immunological profile is decisive. On the basis of three casuistic cases the author adopts a definite attitude to the Sharp syndrome as independent immunopathy. Questions of diagnostics, therapy and prognosis are discussed.

Adult↗