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Biomedical subjects

H Lambert

Publications and source records attributed to H Lambert.

At least 235 records · Page 13Linked to original sources

[Climatologic parameters and myocardial infarction].

535 patients admitted to hospital with myocardium infarct which was confirmed in a determined period and within a 80 kilometers radius from a city of the East of France were compared to the meteorological parameters of the day when the infarct occurred and of the day preceding its occurrence. On one hand, climatic parameters were selected: atmospheric pressure, temperature of the air under shelter, relative humidity, wind speed and wind direction, hydrometeors and electrometeors; on the other hand, parameters of solar and planetary activity: daily flare index, AA index, Ap index or daily planetary index, phases of the moon. The analytic study concerning all acute vascular accidents (infarcts and cerebral accidents all together) enabled to us to notice a higher frequency of vascular accidents in various meteorological circumstances: atmospheric pressure lower than 990 mb, temperature lower than 12 degrees, wind of sector North to South-South West, hoar-frost with fog, rain, snow, first quarter of the moon, daily flare index lower than 530, magnetic activity lower than 6. A factorial analysis of correspondence enabled to us to understand the problem better and to determine "an infarct area" in which main meteorological factors appeared: low or decreasing atmospheric pressure, relative or increasing humidity, clear or increasing solar activity, steady magnetic activity; other factors could play an apparently less important role: low temperature, snow, decrease of wind speed, full moon, wind of sector East to North-East, South-South West. Consequently it appeared in that study that the occurrence of myocardium infarct corresponded to a climatic tendency corresponding to cold, bad or deteriorating weather.

Atmospheric Pressure↗

[Experimental chronic paraquat poisoning. Functional and histopathological pulmonary changes].

An experimental model of pulmonary interstitial fibrosis was attempted in beagle dogs by intravenous administration of weak doses of paraquat. After various trials, the final protocol involved the intravenous injection of 2 mg/kg repeated every eight days for three weeks, and then every 15 days. On the 70th day, areas of localized interstitial fibrosis were observed (less than 10% of the surface of the tissue sections) in an otherwise healthy parenchyma. There was no marked hepatic or renal lesion. The evolution of the inflammatory and toxic processes was followed by the changes: 1) in the animal's weight (drop in weight after the injection of paraquat), 2) in blood gases (essentially drop in PaO2 and in SaO2), 3) in ventilation and respiratory exchanges (increase of VE and ventilatory frequency, decrease of Duco2), and 4) in static pulmonary compliance (distinct fall after injection). All these modifications showed a close relationship to the pattern of the paraquat injections. They receded 15 days after the last injection and reappeared after a new injection. The pulmonary hemodynamic study carried out only at the beginning of the experiment and before the animal was killed showed only a few anomalies (reduction of the average pressure of the right atrium).

Animals↗

[Migration of the Kimray-Greenfield filter when inserting it].

Authors have reported a case of the migration of the Kimray-Greenfield filter to the right ventricle immediately after its release in the inferior vena cava. The delay in the spreading out of the filter seems to have been caused by its insertion into a coagulum formed in the socket guiding in through. This incident often encountered in pulmonary thromboembolism and caused by blood hypercoagulability, justifies higher precautions when inserting the filter.

Female↗

[Acute intoxication by cosmetics].

Intoxications due to cosmetics are of various types, but certain substances may be particularly harmful, especially when the constituants include acetone, boric acid and borates, ethyl alcohol, bromates, formol, methyl alcohol, propylene glycol, thallium, thioglycolate.. Every cosmetic substance may induce accidental intoxications. Most often, fluid cosmetics are absorbed either by children or by feeble-minded subjects. In all intoxication, one must take account of the age and weight of the patient, of the quantity absorbed, of the toxicity and of the constituants of the substance.

Adolescent↗

Gross and microscopic lesions in young chickens experimentally infected with Salmonella enteritidis.

One-day-old and 7-day-old specific-pathogen-free chickens were orally infected with a field isolate of Salmonella enteritidis phage type 13A. Chickens were sequentially euthanatized at various intervals until 42 days of age, and selected tissues were collected for microscopic evaluation. Eleven of 53 chickens (21%) infected at 1 day of age and 2 of 28 chickens (7%) infected at 7 days of age died. Gross and microscopic lesions were more frequent and severe in chickens infected at 1 day of age and in chickens that died (almost all of these were 1-day-infected as well). Lesions were characterized by mild to severe fibrinous pericarditis, airsacculitis, perihepatitis, peritonitis, cecal cores, and enlarged, firm yolk sacs. Gross the microscopic lesions were present from postinoculation day 2 until termination of this study.

Animals↗