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Biomedical subjects

H Lagergren

Publications and source records attributed to H Lagergren.

At least 37 records · Page 2Linked to original sources
PubMed1976

Effect of low-dose heparin on the phagocytic and catabolic function in the reticulo-endothelial system in man during surgery.

The effect of subcutaneous low-dose heparin prophylaxis on the phagocytic and catabolic functions of the reticuloendothelial system (RES) was studied in 10 patients undergoing elective cholecystectomy. The patients were divided into two groups; 5 patients receiving 5 000 units of heparin preoperatively and every 12 hours following the operation and 5 patients given saline at the corresponding time. Each patient served as his own control, when the RES function was tested twice with microaggregated human serum albumin labelled with 125I as a test substance. There was an enhanced phagocytic activity and a correspondingly raised catabolic activity of the RES in patients treated with heparin. The reasons for this are discussed. The results indicate that heparin in low doses has a favourable effect on the RES.

Heparin↗
PubMed1976

A low-threshold, non-dislocating endocardial electrode.

Threshold curves with large and small surface intracardiac pacemaker electrodes are compared. The 2 msec. impulse threshold with a 47 sq. mm. electrode was 3.6 v. (4.3 mA.) on the fourteenth postoperative day, when it reached its maximum, and 2.8 v. (3.1 mA.) one month after the operation. These values were 45 and 30 per cent lower with a 6 sq. mm. electrode. Thresholds increased by about 20 per cent when the impulse duration was shortened from 2 to 0.5 msec. The small surface electrode consumed about 35 per cent less current than the 47 sq. mm. one. A newly designed large area-small surface electrode with the shape of an open cage, seems to have the advantages of less increase in postoperative thresholds and good attachment to the endocardial wall.

Arrhythmias, Cardiac↗