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Biomedical subjects

H L Stewart

Publications and source records attributed to H L Stewart.

At least 55 records · Page 3Linked to original sources

Histamine production by transplantable argyrophilic gastric carcinoid of Praomys (Mastomys) natalensis.

A transplantable argyrophilic gastric carcinoid of Praomys (Mastomys) natalensis contained appreciable amounts of histamine. Dialyzed, microsome-free supernatant of tumor tissue produced definite amounts of histamine in the presence of L-histidine and pyridoxal phosphate. These findings may relate to hypersecretion of gastric acid and formation of multiple ulcers in the stomach and duodenum of Mastomys bearing carcinoids.

Animals↗

Malignant argyrophilic gastric carcinoids of Praomys (Mastomys) natalensis.

Cells of carcinoid tumors which arise in the glandular stomach of old male and female Praomys (Mastomys) natalensis contain argyrophil granules when tissues fixed in formalin are colored with solutions of silver salts. The carcinoids metastasize in about 25 percent of cases, and are transplantable to other Mastomys. Tumor-bearing animals may show gastric and duodenal ulcers and multiple endocrine adenomas.

5-Hydroxytryptophan↗