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Biomedical subjects

H L Jones

Publications and source records attributed to H L Jones.

24 records · Page 2Linked to original sources

Association between primary dentition wear and clinical temporomandibular dysfunction signs.

Dental wear facets often are considered indicators of temporomandibular dysfunction (TMD). Dental wear facets are common in children, but their association with TMD signs is unknown. A reproducible, clinical evaluation of TMD signs for young children shows no statistically significant association between primary dentition wear facets and clinical signs of TMD (P less than or equal to 0.05). Wear facets in young children do not appear to warrant TMD evaluation or treatment.

Chi-Square Distribution↗

Incidental finding of an intranasal foreign body discovered on routine dental examination: case report.

A nasal foreign body was discovered radiologically on an initial dental examination of a young child. The child was a candidate for dental rehabilitation, using nasotracheal intubation under general anesthesia. The parents were unaware of the object's presence, and the child had no nasal symptoms. The child was referred to the Otolaryngology-Head and Neck Surgery Service to have the object removed; this was accomplished successfully without sequelae on an outpatient basis. Dentists and physicians who treat children should be alert to the possible presence of intranasal objects in their patients.

Dental Caries↗

Latex allergy in patients with spina bifida.

Latex recently has been associated with severe intraoperative IgE-mediated anaphylactic reactions. Pediatric patients with meningomyelocele (spina bifida) appear to be specifically at risk for this type of reaction. This article provides background information on the etiology of latex allergies, identifies some commonly used dental products containing latex, recommends some alternatives to use, and suggests precautions the dental practitioner should take when treating high-risk individuals such as spina bifida patients.

Dental Care for Persons with Disabilities↗

Luminal epithelial antigen (LEA.135) expression correlates with tumor progression for transitional carcinoma of the bladder.

Luminal epithelial antigen (LEA.135) expression has been shown to have prognostic significance in breast carcinoma, however its relationship to tumor progression in other forms of malignancy is unknown. This study evaluates LEA.135 expression in bladder transitional cell carcinoma (TCC) and compares the findings with tumor stage and grade, and polyclonal Ki-67 derived cell cycle activity. LEA.135 expression was evaluated by immunohistochemical staining using the streptavidin-biotin method. Staining distribution was graded 0 to 4 and the results were compared with World Health Organisation tumor grade, UICC TNM stage and fraction of actively cycling cells showing positive pKi-67 immunohistochemical staining. In normal bladder epithelium, LEA.135 staining was confined to the luminal surface of superficial epithelium. In lower grade, superficial TCC LEA.135 overexpression was noted and there was a progressive loss of expression in tumors of higher grade (p = 0.0001) and advanced stage (p = 0.0001). No LEA.135 staining was seen in carcinoma-in-situ. Loss of LEA.135 expression correlates with tumor progression for bladder TCC.

Antigens, Neoplasm↗