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Biomedical subjects

H Kuhlmann

Publications and source records attributed to H Kuhlmann.

33 records · Page 2Linked to original sources
PubMed1978

Comparison of different methods of clearance determination.

Clearance determination by compartmental analysis of hippurate renograms was compared in 30 cases to the conventional PAH and to the partly shielded whole body counting technique. Good correlations between compartmental analysis and PAH method (r = 0.96) as well as the whole body technique (r = 0.94) were found. Correlation between PAH and whole body method was not always satisfactory (r = 0.85). In an additional study influence of greater count rates become obvious: correlation coefficients increase from 0.89 (131I-hippurate, n = 97) to 0.95 (123I-hippurate, n = 38). Determination of the divided clearance correlates well (r = 0.95). Using 123I-hippurate all the information available by radioisotopic kidney investigations can be obtained in a one-step procedure.

Aminohippuric Acids↗
PubMed1975

[Use of the adsorption method for regeneration of dialysate in hemodialysis (Redy-system) (author's transl)].

The adsorption method for regeneration of dialysate was introduced as a new principle in hemodialysis. To compare the efficacy of the Redy-system (regenerative dialysis supply system) which utilizes a sorbent cartridge, with the common single-pass systems, 2 patients were dialyzed weekly twice or three times 6 hours over a period of 3 months. Three different types of dialyzers were used: Cordis hollow-fiber, plate dialyzer Lundia Nova 17,0 mu and coil dialyzer Travenol Ultraflo II. Monitoring of serum nitrogen constituents (urea, creatinine, uric acid) showed that the efficacy especially of the hollow-fiber dialyzer was comparable with the single-pass-system. Serial measurements of electrolytes in dialysate and serum, as well as dialysate osmolarity and ammonia indicated that the adsorption method is a safe technique. The advantage of the Redy-system is its independency of a fixed and treated water supply system, since it is able to operate with 5.5 1 tap water, an electrolyte concentrate being added in the recirculation system. Therefore this dialysis device can be installed everywhere, giving the dialysis patient more independency.

Adsorption↗
PubMed1975

Suitability of non-glucose-carbohydrates for parenteral nutrition.

Postoperative parenteral nutrition can only be optimally effective if the characteristics of post-traumatic metabolism are taken into account. Two main possibilities are discussed for the carbohydrate component of parenteral nutrition during this phase: glucose with high doses of insulin or non-glucose carbohydrates (sugar substitutes) possibly in a suitable combination with glucose. The risks as well as the technical and organisational problems involved in the use of them are discussed and the authors prefer the second of the two alternatives. Possible side effects of non-glucose carbohydrates are pointed out and it is shown how these can be avoided by observing dose guidelines. So far a combination of frucose : glucose : xylitol in a ratio of 2 : 1 :1 with a total dose of 0.50 g/kg/hour has been studied most thoroughly. This combination normalises the fat metabolism and improves glucose tolerance without requiring exogenous insulin. Experiences with this combination as well as individual non-glucose carbohydrates on operated patients have been given continuously for up to 7 days and in some cases even for several weeks. No side effects, no deviations from a steady state and no abnormal changes of the laboratory values occurred. The authors are of the opinion that non glucose carbohydrates are necessary if the facilities for frequent blood sugar controls are not available.

Adenine Nucleotides↗