Biomedical subjects

H Kranz

Publications and source records attributed to H Kranz.

34 records · Page 2Linked to original sources

PubMed1980

Myasthenic syndrome: effect of choline, plasmapheresis and tests for circulating factor.

In a patient with myasthenic syndrome neuro-muscular transmission was characterised by depression and facilitation. The relative extent of these two processes varied between muscles, and in the one muscle with time. Guanidine HCl treatment corrected the electrophysiological defect. Oral choline increased muscle action potential amplitude in response to single shocks. Intravenous choline produced features indicating cholinergic autonomic stimulation. Pimozide and plasmapheresis had no effect. Animal in-vivo and in-vitro studies performed to detect a circulating factor which interferes with neuro-muscular transmission were negative.

Action Potentials↗

PubMed1978

Acupuncture analgesia for chronic low back pain.

Preliminary findings are presented of a double-blind, crossover trial comparing the effects of traditional with placebo acupuncture in relieving chronic low back pain. 77 patients completed the study. Following initial assessment and baseline readings, patients had a 4-week course of active or placebo treatment given twice weekly. After a 4 week rest period patients received the alternate treatment, using the same time schedule. A 4 week follow-up period completed the trial. Using visual analogue scale readings as a measure of pain there was no cumulative difference in pain reduction achieved by traditional as compared with placebo acupuncture treatment. Both groups achieved a 55% overall reduction in pain level at the end of the trial, compared with initial baseline readings.

Acupuncture Therapy↗

PubMed1977

Acupuncture--effect on normal subjects.

The effect of acupuncture analgesia on pain threshold was assessed in a group of 60 healthy volunteers. On the average a 60% elevation of the pain threshold was achieved. This effect was seen bilaterally with unilateral acupuncture stimulation. There was no significant difference in the effect produced by three widely separate sites of acupuncture stimulation. The possibility of an additive effect when two sites were simultaneously stimulated was not confirmed in our limited study. Evidence is presented that sensory nerve fibre stimulation may be the basic primary requirement of successful acupuncture analgesia.

Acupuncture Therapy↗

PubMed1977