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Biomedical subjects

H Knolle

Publications and source records attributed to H Knolle.

31 records · Page 2Linked to original sources
PubMed1984

[Behavior of the mucosa of the large intestine following definite urinary diversion].

Multiple biopsies of the mucous and submucous membranes were taken from 50 patients with definitive diversion of urine using the large intestine and evaluated. The varying behaviour of the membranes in connection with uretero- sigmoidostomies , cysto- sigmoidostomies and rectal bladders is discussed. The reactions of the mucous membrane in connection with uretero-intestinal anastomosis are time-dependent. The most serious changes in the mucous membrane occurred in connection with rectal bladders.

Adolescent↗
PubMed1983

[Not Available].

Explore the source record for details and available documents.

History, Modern 1601-↗
PubMed1983

[Critical comparison of various studies on the blocking effect of cytosine arabinoside (cytarabine)].

The therapeutic effect of phase-specific cytostatic drugs depends to a high degree on the time schedule. If the drug has a blocking effect too, then it is important to know, whether the block acts before or after the sensitive phase of the cell cycle. Concerning the S-phase specific drug cytarabine (cytosine arabinoside, 1-beta-D-arabinofuranosylcytosine, ara-C), different and even contradicting answers have been given to this question. In this paper we assume, that the reported experimental facts are reliable, and show that one experiment has been misinterpreted, giving rise to a controversial statement. If this experiment is interpreted well, it urges the conclusion, that ara-C blocks the transition from G1 to S. This is maintained also by experiments with quite a different design.

Cell Division↗
PubMed1977

[Primary nonspecific chronic pleurisy (author's transl)].

Cytologic examinations of pleural exudate and cyto-histological examination of biopsies taken from the pleura give useful contributions in the differential diagnosis of primary chronic nonspecific pleurisy. In the early stage of disease the cellular findings are characteristic and enable easy differentiation of mesothelioma. Later on in primary chronic nonspecific pleurisy alterations of mesothelial cells can be seen which mimic tumorous cells and may be erroneously taken for mesothelioma cells. Quantity and quality of these alterations of nucleus and cytoplasma of mesothelial cells in primary chronic nonspecific pleurisy can be distinguished from tumor cells of mesothelioma by critical evaluation in the majority of cases.

Biopsy↗