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Biomedical subjects

H Klepel

Publications and source records attributed to H Klepel.

At least 37 records · Page 2Linked to original sources
PubMed1983

[Care and delivery of epileptic pregnant patients].

The collective care of women having epileptical fits by gynecologists and neurologists is reported in this paper. Questions of the course of pregnancy as well as the management of delivery are dealt with the help of the collective observation material. The condition of the newborns is described, too. It is especially referred to the fact that the anticonvulsive treatment during the pregnancy has to be maintained, if possible a monotherapy should be used and the plasma level of drugs should be controlled, particularly in the first time of pregnancy. Induction of labor at term has been approved besides of intensive prenatal care with facilities of control by modern equipment. Accumulation of fits during pregnancy or complications by hemorrhage in the newborns were not to be seen. All children with only two exceptions were normally nursed. This regime was not harmful.

Adolescent↗
PubMed1982

[Incidence of electroencephalographic findings in children with stuttering compared to healthy children of the same age].

Results obtained in a single encephalography examination of 79 stuttering and 143 healthy children, both 7 to 10 years old, were compared. While the difference in the frequency between the two groups with respect to focal findings without peak potentials and a focal and generalised tendency to attacks could not be substantiated, 29.1 per cent of all children in the group of stutterers showed a background activity that was too slow for their age. This finding is interpreted as an expression of delayed development which, because of a psychic compensation capacity not corresponding to the age of the test person, offers a favourable basic condition for the development of stuttering. The danger of a misinterpretation of electroencephalographic findings obtained from specific study groups without comparison with a normal population is pointed out.

Brain Damage, Chronic↗
PubMed1982

[Early childhood brain damage and epilepsy. Results of a clinical and electroencephalographic cross-sectional study].

Among 593 children treated as inpatients because of epilepsy, 191 (32.2%) showed indications of a pre- and/or perinatal brain damage. Under partial consideration of another six children (7.8%) with postnatal brain damage, the relations of various clinical and encephalographic parameters between the time of the brain damage and the occurrence of epilepsy were studied. The risk to fall ill with epilepsy after an infantile brain damage is independent of the time the brain damage took place. Children with a perinatal brain damage, however, show the prognostically more unfavourable form of epilepsy with a higher frequency of attacks and greater difficulties of influencing the disease with drugs. Children below the age of six years predominantly showed an occipital localisation of the foci spread over several brain regions and associated with a tendency to attacks while in older children temporally localised foci occurred more frequently.

Adolescent↗
PubMed1981

[Electroneurographic and electroencephalographic findings is patients exposed to hexachlorcyclohexane].

While the health of the general population is not adversely affected by the exposure the pesticides in food and environment, workers, who have during their occupation been intensely exposed to pesticides, exhibit a higher prevalence of slight neurotoxic symptoms. In the present study the electroencephalograms of 3 of a group 10 workmen, who had been continually exposed to hexachlorcyclohexane, show pathological findings. The electromyograms of 8 of these 10 workman demonstrate a disturbance of the peripherical motoneuron. All probands, who exhibit o pathological EEG, also show a polyneuropathy.

Adult↗
PubMed1981

[The treatment of epilepsies with Convulsofin].

The testing of Convulsofin carried out in 220 patients at 14 clinics over a period of six months confirms the international experience gained with valproic acid and sodium valproinate. The main field of application of Convulsofin according to the experience gained will again be the treatment of fits in generalised primary epilepsy for which it permits to carry out a monotherapy to a remarkable extent. The favourable effect of the preparation in photosensitivity could be confirmed. Also in generalised secondary epilepsy and in fits of partial epilepsy. Convulsofin is partly effective, so that it can recommended as a co-medication in the treatment of therapy-resistant forms of these epilepsies which are difficult to treat. Decrease in thrombocytes, transient increase in serum transaminases, gastrointestinal disorders, loss of hair and undesired increases in body-weight were the more frequently occurring side-effects.

Adolescent↗
PubMed1981

[Results of an electroencephalographic cross-sectional study of 2- to 4-year-old children after risk-birth in comparison with to normal-birth children of the same age].

The results of an one time electroencephalographic transversal examination of 146 children with syndrome of intrauterine asphyxia aged from 3 to 4 years are compared with the EEG-findings of 87 children of the same age born normally. 82,9% of the 146 children with higher damage susceptibility and 64,4% of the children of the comparison group have an EEG corresponding to the standard criterions of this age group. 8,2% of the children with higher damage susceptibility and 18,4% of the children born normally show in their resting electroencephalogram focal findings with and without spikes or generalized spike potentials. The results indicate, that by reason of the breadth of variation between normal and pathological EEG-findings in infancy data of the type and frequency of pathological EEG-features have only a value if they are compared with the results obtained from healthy children of the same age.

Asphyxia Neonatorum↗
PubMed1981

[The value of the electroencephalogram for the diagnosis of early childhood brain damage].

Among 406 children with anamnestically and clinically verified infantile brain damage, 356 (87.7%) showed a pathologically changed EEG. In the coordination to clinical symptoms and syndromes, the frequency of the pathological EEG findings was greatest in the group of children suffering from cerebral convulsions (96.7%). It can be derived from the results that the EEG as a method of examination that does not produce any stress and can be carried out in every child is particularly well suited for the verification of the diagnosis of an infantile brain damage.

Adolescent↗
PubMed1975

[Electroencephalographic examinations following strangulation].

An electroencephalogram (E.E.G.) was recorded from 12 patients within 4 hours after strangulation. The tracings were mainly flat and showed severe general alterations. Repeated recordings were performed in 16 patients during the further course at regular intervals until the findings had normalized. Despite the marked initial findings, in 13 patients the basic activity had normalized within 48 hours after strangulation, but often it was asymmetric. Marked asymmetry and focal findings subsided within a year. Only in juvenile patients with initially marked neurological symptoms and subsequent demential course focal findings were found over several years. Contrary to the results of other investigations, spike potentials occurred in 2 patients with tonic-clonic seizures as focal and generalized, resp. steep. waves.

Adolescent↗
PubMed1975

[Incidence of infantile cerebral lesions in children with behavioral disorders].

The delimitation of behavioural disturbances predominantly due to organic brain lesions from those caused by reactions due to environmental factors has practical importance for drug therapy and pedagogic guidance. Figures on the incidence of infantile brain lesions among children with behavioural disorders range from between 20 to 90%. However, comparison of the results is difficult, because different authors followed different aspects for the evaluation of their material. The authors have collected data from 497 children from the 3 to 15 year-old age group who suffer from behavioural disturbances: history, neurological and psychological findings, electroencephalogram, native x-ray picture of the skull, pneumo-encephalogram and echoencephalogram were reviewed for signs and findings suggesting infantile brain damage. Certain signs of intantile brain lesion were found in 28.6% of the children. Among the apparative diagnostic procedures without impairment to the patients, the electroencephalogram proved particularly suited for the support of the diagnosis. The most accurate data on the localization and extent of the lesion are provided by the pneumo-encephalogram. However, its performance is not possible or justified in each child.

Adolescent↗
PubMed1975

[Significance of muscular artefacts during absences].

Among 1.000 absences registered in the electroencephalogram 373 were associated with automatisms. These 373 absences were ascribed to 3 groups with different clinical symptoms according to different timing of the automatisms. In the first two groups automatisms prevail in the motor picture, whereas in the third group of absences adversive movements and/or rhythmic myoclonias were predominant motor elements. The occurrence of automatisms after spike wave potentials confirms, that the true absence may last longer than is expressed by the electroencephalogram (E.E.G.). Similar conditions are known for the behaviour of the autonomous reflexes during the absence. The accordance of clinical and reflex myographical phenomena during the absence suggests a common pathophysiological origin.

Action Potentials↗