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Biomedical subjects

H Kawazu

Publications and source records attributed to H Kawazu.

4 recordsLinked to original sources

[Periodontal disease and implant-supported prostheses].

Periodontal disease is one of the most common dental pathologies which is found in more than 80% of the Japanese adult population. It is also one of the major causes of tooth loss where more than 50% of the tooth are lost due to the periodontal disease. To reconstruct the dental defects, and re-establish the lost functions due to the periodontal disease are very important aspects of the clinical dentistry. Because of the aging society, these services will become even more critical. To lose a tooth not only means a compromised masticatory efficiency, but it has a profound effect on the patient's QOL and ADL. That is why the rehabilitation of the dental function becomes so important. There are two major clinical procedures for the reconstruction of the lost dental functions. They are (1) bridge or partial denture, and (2) implant-supported prostheses. Among other problems, the crown-root ratio of the periodontally involved teeth are less than adequate to serve as an abutment tooth for a bridge, or a clasped tooth for a partial denture. Their prognosis is questionable because of an excessive load over the diseased tooth. Implant-supported prostheses, in contrast, have an excellent long term prognosis because the prosthetic appliances are directly supported by the jaw bone.

English Abstract↗

[Evaluation of imipenem/cilastatin sodium in the treatment of respiratory tract infections].

Imipenem/cilastatin sodium (IPM/CS) was administered to 55 patients with respiratory tract infections (RTI). A clinical evaluation of IPM/CS was carried out in 51 patients, 28 with pneumonia, 4 with pulmonary abscess, 1 with pyothorax, 6 with bronchitis, 9 with bronchiectasis, 1 with diffuse panbronchiolitis and 2 with RTI with chronic obstructive pulmonary disease, and the clinical efficacy rate was 78.4%. Causative organisms were isolated in 23 strains out of 20 patients, such as Staphylococcus aureus 4 strains, Staphylococcus epidermidis 1 strain, Streptococcus pneumoniae 1 strain, Branhamella catarrhalis 1 strain, Haemophilus influenzae 2 strains, Klebsiella pneumoniae 4 strains, Pseudomonas aeruginosa 6 strains, Pseudomonas sp. 1 strain, Acinetobacter calcoaceticus 1 strain, Acinetobacter sp. 1 strain and glucose non-fermentative Gram-negative rod 1 strain. An eradication rate of 70.6% was obtained. An overall eradication rate of main causative organisms in RTI including S. aureus, S. pneumoniae, H. influenzae and K. pneumoniae was 75.0%. Clinical adverse effects were observed in 5 patients, and these were eruption in 2, itching in 1, vomiting in 1 and drug fever in 1. Abnormalities in laboratory test results were observed in 8 patients. These disappeared or returned to normal values after completion or discontinuation of IPM/CS administration. IPM/CS appears to be a useful antibiotic for the treatment of RTI, especially severe infections.

Adult↗