Biomedical subjects
H Kawane
Publications and source records attributed to H Kawane.
Noiseless oxygen concentrator.
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[Smoking among members of the Japan Society of Chest Diseases].
A survey of the smoking habits and attitudes toward smoking among all members of the Japan Society of Chest Diseases has been carried out. Of the 6,224 members of the Society who were sent a voluntary questionnaire, 3,640 (58.5%) responded. Of the 3,640 respondents, 24.8% were smokers, 39.4%, ex-smokers and 35.9%, non-smokers. The prevalence of smoking was lower than among physicians in general in Japan, which is estimated to be 39%, and much lower than the rate for the general male population (61.1%). For ex-smokers, the long-term health risks were the most important reason for giving up smoking, followed by the desire to set an example as medical personnel. The great majority of respondents (91.7-97.3%, depending on smoking status) believed that smoking should be restricted in certain places. Hospitals and clinics had the highest percentage for places where smoking should be restricted. About two-thirds of the respondents also believed smoking should be restricted at medical meetings.
[A case of hemoptysis due to administration of an anti-thrombotic drug].
A 63-year-old woman was referred to our division because of massive hemoptysis (200 ml) after administration of ticlopidine, an anti-thrombotic drug, for prevention of recurrent brain infarction. Ticlopidine treatment was stopped on the first hospital day, thereafter the patient's hemoptysis immediately disappeared. A chest roentgenogram and broncho-fiberscopic examination did not reveal any organic lesion associated with hemoptysis. Laboratory data revealed prolonged bleeding time and decreased platelet aggregation, suggesting that the patient had had a hemorrhagic diathesis associated with the administration of ticlopidine. Although many anti-thrombotic drugs have been recently employed in a variety of clinical cases, the patient's hemoptysis was considered to be due to side effects.
[Squamous cell carcinoma of the lung detected during maintenance hemodialysis which reduced in size after combined CDDP chemotherapy].
A 52-year-old man receiving maintenance hemodialysis for 6 years was referred to our division for further evaluation and additional therapy for cough and hemosputum lasting 2 months, and for examination of a chest roentgenographic abnormality. Transbronchial lung biopsy specimens revealed squamous cell carcinoma of the lung. A total of 8 courses of anticancer chemotherapy with 25-30 mg/m2 of CDDP performed biweekly resulted in a partial remission (56%) but no side effects, including gastrointestinal damage and agranulocytosis. Few cases of lung cancer receiving anticancer chemotherapy with CDDP during maintenance hemodialysis have been reported. Administration methods and dosage of CDDP for patients receiving maintenance hemodialysis were discussed.
[Involvement of infections in asthmatic attack: with special reference to changes in leukocytes and eosinophils].
Changes in leukocytes and eosinophils in 60 patients with non-infectious attack (NIA patients) were compared with those in 50 patients with infection-related attack (IRA patients). In 30 (50%) of the 60 NIA patients, eosinophilia without leukocytosis was observed on admission, and in 23 (76%) of these 30 patients eosinophilia disappeared within 2 weeks of admission. In 36 (72%) of the 50 IRA patients, leukocytosis without eosinophilia was observed on admission, and the periods from the onset of infection to admission were inversely correlated with leukocyte counts. In 22 eosinophilia patients among the 50 IRA patients, the periods from the onset of infection to admission were correlated with eosinophil counts for up to 40 days, and in 13 (76%) of 17 eosinophilia patients not receiving a long-term steroid therapy during admission, eosinophilia continued for more than 2 weeks even after anti-asthmatic and anti-infectious therapies. There was no significant difference in serum IgE levels between the two groups on admission. These results suggest that evaluations of leukocytes/eosinophils on admission and clinical courses are very useful in the management of asthmatic patients with or without bacterial infections.
[Primary lung cancer presenting as a solitary thin-wall cavity].
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[The present situation and the future prospect of pulmonary function test].
We described 6 points of the present situation and the future prospect of pulmonary function tests. The pulmonary function test using different equipment on the same subject gave different results. The results of the pulmonary function test were affected by the subject's efforts. There were no standard prediction equations. Normal subjects and patients with respiratory disease reached the limit of exercise tolerance when the ratio of tidal volume during exercise to vital capacity (VT/VC ratio) approached 50%. Respiratory rehabilitation was evaluated by pulmonary function tests. The development of equipment allowing measurement by subject's quiet breathing is awaited.
Young's syndrome accompanied by medullary sponge kidney.
A 33-year-old man was admitted to our division for further evaluation of repeated fever and purulent sputa of more than 10 years duration. Based on clinical symptoms, chest roentgenograms, bronchograms, seminal examination, testicular biopsy specimen and electron micrograph of cilia from the left main bronchial mucosa, the diagnosis of Young's syndrome was made. A drip infusion myelogram, which was performed because of a persistent hematuria, revealed bilateral medullary sponge kidney, suggesting the involvement of this hereditary disorder in Young's syndrome.
The newest quinolone antibacterial agents and theophylline.
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Wild boars and pulmonary paragonimiasis.
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[Investigation of two cases of a clinically unknown large cell carcinoma of the lung involved with severe stenosis of the bilateral main bronchi].
Reported are two rare cases of a clinically unknown large cell carcinoma of the lung, associated with severe stenosis of the bilateral main bronchi. Case 1: A 61-year-old man was admitted to our hospital because of chief complaints that included a cough, hemosputum, and dyspnea. Based on the bronchoscopic findings that revealed severe stenosis of the bilateral main bronchi and a specimen that was biopsied from tracheal spur, a diagnosis of large cell carcinoma of the lung was made. Although anticancer chemotherapy and irradiation therapy produced a slight improvement in the patient's symptoms, at the 10th hospital week the patient died of suffocation. Case 2: A 77-year woman was admitted to hospital with chief complaints that included a cough and hemosputum. A bronchoscopy revealed severe stenosis of the bilateral main bronchi. After the 4th hospital day the patient complained of increasing dyspnea. At the 9th hospital day the patient died of suffocation. An autopsy results revealed a large cell carcinoma (giant type) of the lung.
Tobacco advertising in Japan.
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Lung cancer and bronchial hyporesponsiveness?
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[A case of squamous cell carcinoma of the lung associated with cavitation after chemotherapy, leading to development of adult respiratory distress syndrome and disseminated intravascular coagulation].
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The cost of domiciliary oxygen in Japan.
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