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Biomedical subjects

H Kasper

Publications and source records attributed to H Kasper.

At least 127 records · Page 7Linked to original sources

Serum lipase activity in chronic renal failure.

In a total of 110 patients with chronic renal failure, 46.4% of the cases had a serum lipase activity exceeding 200 IU, the upper limit of the norm. The degree of reduction of renal function is positively correlated to the frequency of hyperlipasaemia as well as to the elevation of the lipase activity in serum. At a glomerular filtration rate (GFR) of less than 20 ml/min, hyperlipasaemia in chronic glomerulonephritis was found in 75%, significantly more frequent than in chronic pyelonephritis (46.8%). The frequency and degree of hyperlipasaemia was not influenced by haemodialysis. Significantly elevated serum lipase activities were also observed in experimentally produced chronic renal failure in the rat.

Animals↗

Concentration of vitamin A, retinol-binding protein and prealbumin in serum in response to stress: A contribution to the prevention of stress ulcers by means of vitamin A.

Starting from clinical observations indicating a reduction in the stress ulcer rate by parenteral administration of high doses of vitamin A after burns, traumatic damage and surgical operations, the pattern of vitamin A, retinol-binding protein (RBP) and prealbumin (PA) concentrations in serum was studied in a number of patients with multiple traumas (group 1; n equals 32), cranial-cerebral lesions and postoperative conditions (group 2; n equals 27) and patients having undergone gynecologic operation (group 3; n equals 15); the results obtained were compared with the concentrations determined preoperatively and the normal values as reported in the literature. It was seen that the concentrations in the 3 groups were significantly reduced for all 3 parameters. This fall in concentration was observed not only when food was withheld but also with optimal supplies of essential nutrients. Intestinal hemmorrhages occurred in altogether 6 patients of groups 1 and 2 who exhibited serum vitamin A concentrations in the extremely low range and in the lower normal range.

Adolescent↗