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Biomedical subjects

H Kalkowski

Publications and source records attributed to H Kalkowski.

At least 19 recordsLinked to original sources

[Peripheral embolism of hemostasis collagen (VasoSeal)].

VasoSeal is a purified bovine, absorbable collagen plug currently successfully used to close the femoral arterial puncture site after cardiac catheterization under full anticoagulation. Up to now there has been no experience with potential complications. We observed acute ischemia in the right lower leg of 2/100 patients 36 resp. 24 h after successful closure of the puncture site with VasoSeal. Angiography confirmed acute occlusion of the distal A. poplitea dextra. A 25-mm resp. 50-mm long cylindrical foreign body embolus was removed with a Fogarty-catheter by retrograde indirect embolectomy. Histopathology confirmed a fresh collagen clot with appositional thrombosis.

Aged↗

[The Rostock artificial heart--current status and perspectives].

The authors report on their experiences gained by animal experiments (calf) and their attempts (human corpses) concerning adaptation of the apparatus to the human thorax. At the present time they do not see a chance for its routine clinical use. The main reason why is the impossibility to install the extrathoracic driving system into the thoracic cage and last not least the wear of the material used for the heart chambers.

Animals↗

[Treatment of thrombotic occlusion of the pelvic and extremity veins. Comparison of three different types of treatment].

Out of 102 patients suffering from deep venous thrombosis of leg and pelvis 46 of them underwent thrombectomy with excellent results in 73.9%; in 23.9% the result was good, one patient came to death due to pulmonary embolism. In no case a postthrombotic syndrome could be traced. 23 patients (22.5%) underwent thrombolysis by Streptokinase. In no case the result was excellent, in 19 patients this treatment showed satisfactory results, 2 patients developed a postthrombotic syndrome, 2 patients died of haemorrhage. 33 patients (32.25%) were treated by a combination of heparin and acetyl-salicylic acid. A good result could only be obtained in 2 patients, a postthrombotic syndrome developed in the remaining 31 cases.

Adult↗

[Experiences with the Rostock artificial heart].

A totally artificial heart--the Rostock totally artificial heart (Rostock TAH) was implanted in calves. We can give the following deductions after 27 examinations: -- The Rostock TAH was tested successfully in endurance test about 7 months; it show no sign of wear. -- The surgical technique of the implantation was standardised and a successful experimentation is possible. -- The longest survival time was 15 days. The hemodynamic early results were very good in 3 other animals. -- Modifications of the Rostock TAH were taken up relating to the dimensions of the artificial ventriculi and by mounting a screw cap for avoiding an air embolism. -- Adaption tests in the corpse show that the present form of the artificial heart is not ideal for a possible application in man. -- The problem is still existing in developing a suitable drive system locates intrathoracically. The present drive and control system on a pneumatic base is qualified only for the animal experiment but not for a possible application in man.

Anesthesia, General↗

[Intrathoracic parallel heart transplantation in the dog].

The authors report on intrathoracic parallel heart transplantation which was experimentally tried on 10 mongrel dogs. The described technique is advantageous since it can be performed without extracorporeal circulation. The results of hemodynamic studies on graft and recipient heart vindicate further employment of this technique to study several problems of heart transplantation still unsolved.

Animals↗