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Biomedical subjects

H Kaita

Publications and source records attributed to H Kaita.

At least 37 records · Page 2Linked to original sources
PubMed1987

Swa: a subdivision.

For some time, anomalous serological reactions have been observed when the same anti-Swa sera are tested against red cells from different individuals reported as Sw(a+). A comparative collaborative study using the same collection of Sw(a+) cells and anti-Swa sera was undertaken by 4 reference laboratories, and it was found that Swa represents a heterogeneous group of antigens that can be subdivided into two categories. Both categories, Sw(a+) 700:41 and Sw(a+) 700:-41, were shown to be inherited.

Blood Group Antigens↗
PubMed1987

The Yt blood group system (ISBT No. 011). Genetic studies.

Allele frequencies of Yta (YT1) and Ytb (YT2) in a series of 659 random Canadian Caucasians are comparable to those in European populations: 0.9469 and 0.0531, respectively. Inheritance of Yt phenotypes in 1,077 children in 286 selected families are in accordance with expectation on the basis of Mendelian codominance. Linkage studies exclude YT from chromosomal segments 1p36-1p22.1, 4q13-4q28, the section of chromosome 9 bounded by AB0 and AK1 and from the chromosome 19 linkage group bounded by LE and SE. Evidence is presented for a possible location of YT on the short arm of chromosome 6 distal to F13A.

Blood Group Antigens↗
PubMed1987

The LW:C3 recombination fraction in female meioses.

No recombinants between LW and C3, using a C3 DNA probe, were observed in 16 female meioses: z 4.216 at theta = 0.00. Combined with the data of Sistonen (1984) the recombination fraction between LW and C3 is estimated to be 0.09 (z 3.773) in females.

Antigens↗
PubMed1987

Population study of electrophoretic polymorphisms of red cell enzymes and plasma proteins in Caucasian Canadians.

Blood samples from a random series of Canadian Caucasians were phenotyped for 28 red cell enzyme systems and eight plasma protein systems. Polymorphism was found in 17 and rare variants in 11 of the systems. Allele frequencies are presented for these; distribution of phenotypes is in accordance with the Hardy--Weinberg equilibrium theory. In a complementary study of families there was no evidence of de novo mutation in any of the 36 systems and they allowed a minimum estimate of the frequency of null alleles in the ADA, C2, and GPT systems.

Alleles↗
PubMed1987

The sequence of chromosome 3 loci AHSG:TF:CHE1.

A large Hutterite kindred was examined for possible linkage between the chromosome 3 markers; cholinesterase (CHE1), transferrin (TF), and alpha-2HS glycoprotein (AHSG). Linkage between TF and AHSG was suggested in males (z = 1.515, theta = 0.08) and between CHE1 and TF(z = 0.661, theta = 0.21). However, linkage between CHE1 and AHSG in males was not established. Based on lods and a nuclear family informative for all three loci a possible chromosomal alignment for the loci is presented.

Cholinesterases↗
PubMed1985

Multiplicity of genetic polymorphisms of blood in the Schmiedeleut Hutterites.

Ninety-eight alleles in 38 polymorphisms of blood are identified in the Schmiedeleut Hutterites. The study was initiated because of the presence of Wda, an allele found almost exclusively in Hutterites. Eight of the other alleles also have an exceedingly low incidence in a random white population: r'' (.006), R2w (less than .001), LWb (less than .01), ESD*rare (less than .001), GPT*0 (.004), NP*4 (less than .001), GOT2*3 (.001), and C6*0 (.002). The occurrence of this many rare alleles in a population with an estimated maximum of 124 ancestral genomes was surprising but consistent with observations in other isolates. The degree of heterozygosity and large family size make the population ideal for genetic linkage studies.

Blood Group Antigens↗
PubMed1984

A "new" low incidence red cell antigen, NFLD.

A "new" low incidence red cell antigen, NFLD, is described. It was found in a Caucasian family and is inherited as an autosomal dominant. The antigen is not part of the AB0, MNSs, Duffy, Kidd, or Yt blood group systems and probably does not belong to the Rh or Kell blood group systems.

Blood Group Antigens↗
PubMed1981

A "new" low incidence "Hutterite" blood group antigen Waldner (Wda).

A "new" red cell antigen has been found so far only in members of Hutterite kindreds with the surname Waldner. The antigen, Wd(a), is inherited as an autosomal dominant and is not part of the ABO, Chido, Colton, Dombrock, Duffy, Kidd, MN, P, or Rh blood group systems.

Antigens↗
PubMed1979

Genetic linkage between the Radin and Rh blood group loci.

Lods of +3.89 at a recombination fraction (theta) of 0.10 and recombinant:nonrecombinant counts of 2:16 indicate linkage between the Rd and Rh blood group loci. The possibility that Rd is the same as Sc is discussed.

Blood Group Antigens↗