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Biomedical subjects

H Kaźmierczak

Publications and source records attributed to H Kaźmierczak.

At least 19 recordsLinked to original sources
PubMed2001

[Hyperlipidemia in patients with inner ear disturbances].

The aim of this study was to evaluate the occurrence of hyperlipidemia in patients suffering from vertigo, and/or tinnitus and/or hearing loss of unknown origin. 48 patients (25 women and 23 men) were included into this study. All patients had a negative previous medical history of any metabolic, cardiovascular or neurological disorders. Our results were compared to the control group of 31 healthy persons (16 women and 15 men). All subjects had a complete neurootologic examination, appropriate audiometric and vestibular studies. In biochemical evaluation lipid phenotype studies were performed. Hyperlipidemia were classified according to Friedricson criteria. There were some differences in lipid phenotype and severity of hyperlipidemia between this two group.

Adult↗
PubMed2001

Visuoocular reflexes in presbyvertigo.

Using electronystagmography, we tested 100 patients (ages 65-80 years) manifesting the clinical signs of presbyvertigo, for the purpose of demonstrating their visuoocular reflexes. We administered not only simple optokinetic and eye-tracking stimuli but caloric modification of each one as well (with contrary directed optokinetic trace movement). The results were compared with those obtained in a group of 40 healthy subjects between the ages of 20 and 25 years. In the older group, we observed a statistically significant increased frequency of asymmetry of optokinetic nystagmus and pathological patterns revealed by the eye-tracking test and caloric modification of both the optokinetic and eye-tracking tests. We discuss the hypothetical predominant localization of age-dependent changes, with emphasis on the disturbances of visual-vestibular integration, on the basis of data obtained from anamnesis and other electronystagmographic findings.

Aged↗
PubMed2001

Metabolic disorders in vertigo, tinnitus, and hearing loss.

Vertigo, tinnitus, and hearing loss are common complaints among populations of industrial countries, especially in persons older than 40 years. Numerous agents are known to incite vertigo, tinnitus, and hearing loss, among them hyperinsulinemia, diabetes mellitus, and hyperlipidemia. In this study, we proposed to assess the occurrence of hyperinsulinemia, diabetes mellitus, and hyperlipidemia in patients suffering from vertigo, tinnitus, or hearing loss of unknown origin. Results of various tests in 48 patients were compared to those in 31 control subjects. Assessments of body mass index, blood pressure, and laryngological, audiometric, and electronystagmographic parameters were performed in all study participants. An oral glucose tolerance test was used to evaluate insulin levels, and lipoprotein phenotyping served to determine cholesterol, triglyceride, and lipoprotein levels. Patients were found to be significantly more overweight (on the basis of body mass index) than were the control subjects. Hypertension was more common among patients than controls, but the difference was significant only between the men in the two groups. Disturbances of glucose metabolism were found in 27.1% of patients but in only 9.7% of controls. Diabetes mellitus was not present in any controls but was identified in four patients. Hyperinsulinemia was almost twice as common in patients as in controls. Only the occurrence of hyperlipoproteinemia seemed not to differ between patients and control subjects. We conclude that such disturbances of glucose metabolism as diabetes mellitus and hyperinsulinemia may be responsible for inner ear diseases, whereas the role of disturbances of lipid metabolism remains vague.

Adult↗
PubMed2000

[The vestibular system and migraine in children].

Migraine in childhood is relatively common disease. Although clinical practice and scientific publications recognize frequent association of migraine and vestibular disorders, relationships have yet to be well defined. In present study the vestibular function was extensively tested in 20 children suffering from migraine. All the patients underwent complete neurootological examination including tonal threshold audiometry, testing of vestibulo-spinal reflexes--Romberg and Unterberger-Fukuda tests, Dix-Halpike test for BPPV, videonystagmography. On videonystagmography each patient was evaluated regarding: calibration, spontaneous nystagmus, gaze nystagmus, eye tracking test, optokinetic and positional nystagmus, and caloric testing. The same procedure have been performed regarding control group comprised of 15 healthy. All the patients with migraine presented abnormalities in vestibular testing. Analysis of the results showed that: functional state of structures forming both visuo-ocular and vestibulo-ocular structures was altered in all the migraine patients evaluated in the study, pathological findings suggest mainly central localisation of vestibular dysfunction in children suffering from migraine, the number of pathological VNG findings seems not to be correlated with the type of migraine.

Adolescent↗
PubMed2000

[Risk factors for inner ear diseases].

The aim of this study was to evaluate the occurrence of obesity and arterial hypertension in patients suffering from vertigo, and/or tinnitus and/or hearing loss of unknown origin. 48 patients (25 women and 23 men) were included into this study. All patients had a negative previous medical history of any metabolic, cardiovascular or neurological disorders. Our results were compared to the control group of 31 healthy persons (16 women and 15 men). All subjects had a complete neurootologic examination, appropriate audiometric and vestibular studies. In most cases inner ear pathology was recognised. BMI, systolic and diastolic blood pressure were measured in all cases. Patients were overweight significantly more often comparing to the control group. Systolic and diastolic hypertension was found significantly more often in men from the patients than control group.

Adult↗
PubMed2000

Electronystagmographic study in chronic schizophrenia.

The authors reached the neurological and psychiatric diagnosis of chronic schizophrenia in 20 patients after examination of both vestibulooculomotor and visuooculomotor reflexes on electronystagmography. The type and intensity of the disease were established on adequate scales, and the entire group was tested in the remission stage, during the absence of psychotic signs. Electronystagmographic study, particularly the eye-tracking test with caloric modification, revealed the significant pathology of optokinetic nystagmus. The disturbances of the suppression effect of fixation on caloric nystagmus were observed in one-half the cases. Caloric stimulation demonstrated no case of canal paresis and a very small amount of directional preponderance.

Adult↗
PubMed1999

[Electrophysiological examination (ENG, EEG) in Alzheimer's disease].

The aim of the study was the electronystagmographic and electroencephalographic examination in patients with clinical diagnosis of Alzheimer's disease. The results showed that visual-oculomotor and vestibulo-oculomotor disturbances have had the central origin. ENG and EEG examination showed the lesions of both frontal and temporal cortes in these patients.

Aged↗
PubMed1999

[Vestibular findings in children's epilepsy].

20 children between ages 6 and 15 who suffered from epilepsy classified according to suggestions of International League Against Epilepsy to partial seizures evolving to generalized seizures were tested otoneurologically. The aim of the study was to estimate the frequency and location of vestibular disturbances coexisting with the disease. Subjective and objective (using electronystagmography--ENG--and videonystagmography--VNG) otoneurological study was performed. Dizziness was noted in most cases. Nobody demonstrated normal ENG/VNG recordings and the character of the pathology suggested its central origin. Eye-tracking proof and optokinetic nystagmus (cortical and subcortical) revealed to be most helpful during diagnostic procedures. No correlation between the location of EEG pathological patterns and ENG pathological signs was proved.

Adolescent↗
PubMed1998

[The role of the histaminergic receptor in the vestibular habituation: an experimental study].

The aim of the study was to determine the role of histaminergic H1, H2 and H3 transmission on the acquisition of vestibular habituation in pigeons. Rotatory training was used and the intraperitoneal injections of the agonists and antagonists of receptors described above were performed before each training. The results showed that agonists of H1 and H2, and H3 antagonist facilitate vestibular habituation. On the other hand, H1 and H2 antagonists restrain this process.

Animals↗
PubMed1998

[The role of neurotransmitters in the vestibular habituation: an experimental study].

The aim of the study was an evaluation of the influence that agonists and antagonists of the cholinergic and adrenergic transmission have on the acquisition and retention of habituation in a pigeon. Habituation training was performed by a rotatory test, under specific drugs influencing cholinergic and adrenergic transmission. The results show that after injection of a cholinergic antagonist or adrenergic agonist the acquisition of habituation is quicker; on the contrary, cholinergic agonists or adrenergic antagonists make this process slower. These drugs do not have any influence on the retention of habituation.

Animals↗
PubMed1997

Vestibular habituation--the effect of cholinergic, adrenergic and histaminergic agents on the process.

Vestibular habituation-the effect of cholinergic, adrenergic and histaminergic agents on the process. The role of cholinergic, adrenergic and histaminergic transmission on the acquisition of vestibular habituation in pigeons is reported. 1. Cholinolytic, adrenomimetic and histaminergic agents probably clear the way for vestibular habituation in pigeons. 2. The cholinomimetic, adrenolytic and antihistaminergic effects probably inhibit the acquisition of habituation in these animals.

Adrenergic Agents↗
PubMed1996

[The study of visual-oculomotor disturbances in otoneurological diagnosis].

The subject of work was the evaluation of diagnostic value of optokinetic nystagmus in inhibition of caloric nystagmus. Examination was performed in healthy subjects and in the peripheral and central vestibular pathology. The results of investigations show that this inhibition test is useful for differentiation peripheral and central vestibular pathology, especially supra- and subtentorial CNS lesions. Pathological result of this test in cerebellar lesions and brain-stem lesions suggest the role of these structures in the mechanism of optokinetic nystagmus.

Cerebellum↗
PubMed1995

[Experimental investigation of habituation transfer].

The subject of investigation was the possibility of the transfer of habituation. In 20 pigeons frequency of optokinetic and postrotatoric head nystagmus was established. Then in 10 birds optokinetic habituation training and in 10 remaining pigeons rotatoric habituation training were performed. After acquisition of habituation in the first group, frequency of postrotatoric head nystagmus and in the second group frequency of optokinetic head nystagmus were defined. The transfer of optokinetic habituation to the rotatoric test was confirmed. The inverted process was not observed.

Animals↗
PubMed1995

[The influence of experimental hemispherectomy and hemicerebellectomy on the acquisition and retention of habituation in pigeon].

The subject of investigation was the analysis of the acquisition and retention of the vestibular habituation in pigeons after hemispherectomy or hemicerebellectomy. The habituation training was performed using rotatory test. The frequency of head nystagmus and postural reflexes were examined before and after acquisition of habituation and some days later, for evaluation of retention. Our results suggests that hemispherectomy does not inhibit acquisition of habituation but retention of this phenomenon is shorter at that time. The hemicerebellectomy makes impossible the vestibular habituation.

Animals↗
PubMed1995

[The usefulness of cupular-otolith integration examination in postrotary nystagmus for estimation of otolith function].

The aim of work was the influence of otolith irritation on duration of postrotatory nystagmus. The otolith excitation was performed by the head bend on the shoulder homolateral or heterolateral for the direction of postrotaroty nystgamus. The results show the difference in time duration of nystagmus in these two manoeuvres. In author opinion this differentiation makes possible separate ototlih examination.

Adult↗
PubMed1995

[Otolaryngologic symptoms from tumors of the posterior cranial fossa].

The aim of the paper was the estimation of the otolaryngological signs in the patients with the tumor of posterior cranial cavity. Each one was underwent the otoneurological diagnosis inclusive of electronystagmography. The most frequent symptoms we noticed were headache, vertigo together with cerebellar signs and disorder of the VII, VIII and IX-th cranial nerves, The ENG seemed to be a useful method in a localizing process of intracranial damages.

Adult↗
PubMed1995

[Epidemiology of malignant neoplasms of the upper respiratory tract and oral cavity in the Bydgoszcz region].

The authors performed epidemiological analysis of malignant neoplasms of the nose, paranasal sinuses, throat, tongue, larynx and salivary glands in Bydgoszcz area. All the patients were treated in the Otolaryngological Clinic of Medical Academy in Bydgoszcz. Patient's sex, age, profession, living and environmental conditions as well as histopathological diagnosis were taken into analysis. The data were referred to various regions of Bydgoszcz province, which were elucidated on the basis of microclimate conditions, industry, soil conditions, density of the forest area, and cultivated agriculture plants. Correlations between occurrence of oral cavity and the upper respiratory tract malignant neoplasms and living conditions as well as kind of profession in different parts of Bydgoszcz province were estimated.

Adult↗