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Biomedical subjects

H K Ghosh

Publications and source records attributed to H K Ghosh.

33 records · Page 2Linked to original sources

Experience with a simplification of the petroff method for laboratory diagnosis of mycobacteria in sputum.

In the original Petroff procedure sputum is digested with NaOH and the centrifuged deposit neutralized with HCl before culturing. A modification in which digestion is arrested by dilution with water and the sediment is seeded on buffered media is simpler, quicker, safer and in our hands seems to give a greater number of positive smears and cultures for mycobacteria with less overgrowth by contaminants. The usefulness of regular smear examinations for excluding tuberculosis in nonspecific chest complaints is questioned.

Bacteriological Techniques↗

Terminal exacerbation of chronic melioidosis in New South Wales.

A fatal case of melioidosis, thought to be the third recorded from New South Wales, is presented. Infection probably occurred in Queensland. The patients presented with a subcutaneous abscess complicated by pyaemia, extensive lung involvement and septicaemic shock. The diagnosis was bacteriologically confirmed shortly before death, by isolation of Pseudomonas pseudomallei from blood, pus swabs and tracheal aspirates. There is a need for greater awareness of this disease in persons who have resided in South-East Asia and in North-Eastern Australia.

Adult↗

Eosinophilic meningitis (angiostrongylosis): a probable case.

A probable case of eosinophilic meningitis is described. This report is thought to be the first of a case of this disorder diagnosed in New South Wales, although infection probably occurred in Queensland. The life cycle of the parasite Angiostrongylus cantonensis is outlined briefly and the clinical manifestations of this disease are discussed. Treatment with thiabendazole seems to have been beneficial to this patient.

Adolescent↗

Role of bacterial growth inhibitors in urine in diagnostic culture.

Frequently no growth is obtained on ordinary cultures from urines of patients with typical symptoms of infection, and sometimes not even from those with pyuria. The possibility that this could be due to antibacterial substances-whether endogenous or exogenous from non-specific medication-has been investigated.

Anti-Infective Agents, Urinary↗