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Biomedical subjects

H J Pesch

Publications and source records attributed to H J Pesch.

84 records · Page 5Linked to original sources

Portal hypertension caused by partial nodular transformation of the liver.

The course of the disease in, and the necropsy on, a 46-year-old woman with partial nodular transformation of the liver are described. This is, as far as is known, the fifth case to be reported. On the basis of results obtained from clinical tests partial nodular transformation of the liver was assumed. Seven months after the first episode of haematemesis and after numerous haemorrhages, the patient died. The morphological picture of the liver confirmed the tentative diagnosis. In spite of opinions to the contrary (Ingelfinger, 1967), the clinical picture of portal hypertension, can, by reason of the morphological findings, be clearly differentiated from hepatic cirrhosis and other nodular changes in the liver.

Esophageal and Gastric Varices↗

[Aging bones as a paradigm for individual differences in aging].

The physiological fate of every organism and its organ systems is aging which--as general opinion has it--after the age of 50 leads to a measurable mass of bone loss in the human skeletal system. This so-called physiological osteoporosis, however, affects the individual bones differently: Thus, the volumetric density in the neck of the femur and in the lower three lumbar vertebral bodies (LVB) decreases by 30%, but not in the lower three cervical vertebral bodies (CVB), while in the thyroid cartilage it increases constantly from the age of 15/20 years onwards. From the functional point of view, the so-called osteoporosis of old age is thus an expression of an aging bone adapting to the physical activity of the body, which, as such--just like the bone of the younger adult--merely reflects the current stressing of the cancellous bone by the locomotor system. Osteoporosis proper, in contrast, is a manifestation of disease of the bone causing clinical symptoms, in which underlying osteopenia results in fractures and spontaneous deformations.

Adolescent↗