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Biomedical subjects

H J Peiper

Publications and source records attributed to H J Peiper.

At least 73 records · Page 4Linked to original sources
PubMed1976

[Clinical results of esophagojejunoplication (author's transl)].

Indications, surgical technique, and clinical results in esophagojejunoplication are shown. In 46 patients the indication for total gastrectomy in 20 cases was a benign disease and in 26 cases cancer of the stomach. An essential feature of this method is the construction of a jejunal cuff, which is drawn around the anastomosis and the terminal esophagus. Particular advantage is the security of the anastomosis; we have observed only three leakages and these were without complications (6.5%). The fatality rate was 8.5%, and the total rate of complications was 26.1%. With 30 surviving patients a postoperative follow-up was carried out, the results of which are shown. Jejunoesophageal reflux occurred in only 7.9% of these patients.

Esophagus↗
PubMed1976

[Cartilaginous tumors of the skeleton].

Chondrogenic tumors of the skeleton are divided into 6 separate groups: 1. chondroblastomas 2. chondromyxoidfibromas, 3. osteochondromas (cartilaginous exostoses), 4. enchondromas, 5. periostal chondromas, and 6. chondrosarcomas. The presentation of the different types of tumors demonstrates the pathogenesis, pathology, clinical findings, treatment, and prognosis. States of tumors before and after operative treatment are illustrated.

Aged↗
PubMed1975

[Results of operative treatment of chronic pancreatitis, especially exocrine and endocrine functions (author's transl)].

Studies were undertaken in 40 patients with chronic pancreatitis six months to seven and a half years (mean 25 months) after operation, results being compared with pre-operative findings. Measurements included: exercise capacity, absence of pain, body weight, endocrine (36) and exocrine (25) pancreatic function. Almost all patients returned to full or only slightly impaired activity, were free of pain or had less pain and weight increase. Exocrine pancreatic function (secretin-pancreozymin test and faecal fat) was noted in 11 of 25 patients. In another 11 pre-operative progression was arrested. But endocrine function improved in only three of 36 and worsened in 13 (manifestation of subclinical diabetes in eight, worse glucose tolerance in five). The results justify a more active surgical approach in the treatment of chronic pancreatitis in order to save the patients from an often long and painful "burning out" of the disease on purely conservative treatment. Furthermore, exocrine pancreatic function, at least, is maintained or improved.

Adolescent↗
PubMed1975

Cell renewal of gastric mucosa in Zollinger-Ellison syndrome.

In Zollinger-Ellison patients the gastric mucosa is characterized histologically by hyperplasia both of the glands and the gastric pits. The fundic gastric mucosa is thickened with a marked increase of the specific glandular cells. In-vitro autoradiographic examination shows a significant increase in proliferation of the stomach epithelial cells in three patients with hypergastrinaemia. The mean generation time was diminished from 72 plus or minus 2 in controls to 45 plus or minus 4 hours in the Zollinger-Ellison patients owing to a reduction of the G-1 phase from 62-63 to 36-37 hours. The labelling index (3-H-index) was increased from 10.0 plus or minus 0.2 to 15.7 plus or minus 1.8%. The DNA synthesis phase, the G-2 phase, and the mitotic time were not altered compared to the controls.

Adult↗