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Biomedical subjects

H J Nevyas

Publications and source records attributed to H J Nevyas.

10 recordsLinked to original sources

Acute band keratopathy following intracameral Viscoat.

Band keratopathy developed rapidly in two patients following uneventful phacoemulsification and intraocular lens implantation using BSS Plus (balanced salt solution enriched with glutathione, bicarbonate, and glucose) infusion and Viscoat (chondroitin sulfate-sodium hyaluronate), which was left in the anterior chamber at the conclusion of the procedure. Histopathologic evaluation of corneal tissue obtained from one patient at the time of edetic acid chelation revealed histochemical findings consistent with anterior stromal calcification. To investigate a possible relationship between Viscoat and the rapid onset of band keratopathy, Viscoat formulated with varying concentrations of phosphate buffer was injected intracamerally into 42 rabbit eyes. Within 48 hours, clinically obvious corneal opacification developed in nine (47%) of 19 eyes injected with the commercial preparation of Viscoat. Also, similar opacification developed in ten (77%) of 13 eyes that received Viscoat formulated with twice the phosphate concentration of the commercial preparation. Band keratopathy did not develop any of ten eyes that received Viscoat with one fourth the commercial phosphate concentration. In selected opacified corneas, the presence of phosphorus in the subepithelial and posterior corneal stroma was confirmed by histochemical stains and energy-dispersive x-ray analysis.

Aged

Giant cell arteritis with normal erythrocyte sedimentation rate: a management dilemma.

Two patients with cranial arteritis and normal erythrocyte sedimentation rates of 13 mm/hr. and 26 mm/hr. are presented. One patient became totally blind awaiting temporal artery biopsy. The other patient was a challenge in titrating increased steroid dose with cardiovascular complications against decreased steroid dose with worsening of visual and neurologic problems. Available tests may be negative in active disease. The clinical picture is paramount in decision making, and a high index of suspicion is mandatory. Since a delay of twenty-four hours may be critical, steroids usually should be started as soon as an erythrocyte sedimentation rate has been drawn, without waiting for a biopsy. Once steroid therapy has been started, temporal artery biopsy should be performed conveniently soon, regardless of the erythrocyte sedimentation rate.

Aged

A wireform surgical drape-retractor.

I devised a malleable plastic-coated wireform drape-retractor that increases patient comfort during surgery by keeping drapes off the nose and mouth. It is small and does not interfere with the surgeon's hand movements.

Humans

An improved operating room demagnetizer.

An operating room demagnetizer that utilized a pulsed, smoothly decaying oscillating magnetic field is described. The instrument can demagnetize a number of surgical instruments at one time and can provide instantaneous and complete demagnetization.

Magnetics

Small-incision capsular fragment forceps.

Capsular fragment forceps were designed especially for small-incision microsurgery. The blades were fashioned in a bayonet design so that capsular material may be grasped by the tip of the forceps while iris is not pinched by the heel of the forceps.

Cataract Extraction

A foot-pedal controlled valve for intraocular irrigation.

A solely mechanical foot-pedal operated valve for control of intraocular irrigation provided independence from an assistant and allowed accurate adjustment of flow. It was particularly useful during cataract aspiration, vitreous cutting, and intraocular lens implantation.

Cataract Extraction