[Selective denervation with the botulinum toxin as a therapeutic principle in the gastrointestinal tract].
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Biomedical subjects
Publications and source records attributed to H J Maurer.
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To our knowledge extraosseous osteosarcoma has not been reported in the Malaysian literature. We report a case of extraosseous osteosarcoma which was treated by intra-arterial chemotherapy, embolization, wide resection of tumour and salvage of limb with good functional result.
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In a randomized double-blind trial performed in 58 offices of internists and general practitioners, Persumbran (25 mg dipyridamole + 10 mg oxazepam) was compared with placebo. A total of 344 patients with mild-to-moderate angina pectoris in whom the tranquilizing effect of oxazepam appeared meaningful and who had already previously been treated with Persumbran, were admitted to the study. In more than 50% of the patients, coronary heart disease had been confirmed by ergometry or angiography. The dose administered during the trial was oriented to the previous treatment with Persumbran. During the first week of the trial, all patients received a placebo; in the following 6 weeks, one group of patients received Persumbran, the other was continued on placebo. If required, nitroglycerine capsules were to be allowed. The patients in the Persumbran group registered an average of 18% fewer "mild", 50% fewer "moderate", and 35% fewer "severe" attacks of angina pectoris; the total number of attacks, weighted for severity, was significantly lower than in the placebo group. The use of nitroglycerine capsules was 39% less in the Persumbran group as compared with the placebo group. Also episodes of "prolonged cardiac complaints whose duration was not exactly definable" were significantly less frequent in the Persumbran group. Moreover, restrictions in activity due to cardiac complaints, as recorded by the patients were significantly fewer in the Persumbran group.
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At the end of bulk processing of contrast media, water is added. If this is not done properly, the result may be that contrast medium is eventually replaced by water, so that a few bottles of useless "contrast medium" may end up in the hands of the user.
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In this retrospective study, the results of Doppler sonography and phlebography are compared. In about 30% cases the diagnosis of thrombosis made by Doppler sonography could not be confirmed. Agreement was better in patients with acute thrombosis or following pulmonary emboli than in those with a longer history of swelling of the lower extremities. These results agree with the findings of other authors using impedance plethysmography; this also shows lack of agreement in about 30% of the cases.
The authors demonstrate on the basis of a case that in known thrombosis follow-up of the course of the disease via Doppler sonography will not suffice to determine the success of the treatment. Attention is drawn to the importance of detailed examination in respect of completion or continuation of treatment.
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