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H J Kolmos

Publications and source records attributed to H J Kolmos.

At least 19 recordsLinked to original sources
PubMed2001

Role of the clinical microbiology laboratory in infection control--a Danish perspective.

Clinical microbiology laboratories in Denmark are located in hospitals and staffed by clinical microbiologists who are clinically trained medical doctors. Each county has its own clinical microbiology unit, serving a population of 0.3-0.6 million. The responsibilities of clinical microbiology unit cover many different aspects of infection control. They include detection of outbreaks of hospital-acquired infections, screening for multi-resistant organisms, advice to clinicians about disinfection, sterilization and isolation procedures, and the rational use of antibiotics. Clinical microbiologists work closely with infection control nurses. Together they form the infection control team, which is the executive part of the local infection control committee. The infection control team is also the main body responsible for the development of guidelines, which are approved by the regional infection control committee. The local microbiology laboratories work in close contact with the National Department of Hospital Hygiene and other reference laboratories at the State Serum Institute. The present structure of infection control was established 25 years ago. The main aim at that time was to decentralize infection control and establish facilities as close to clinicians and patients as practically possible. This has solved most basic problems related to infection control, and compliance by clinicians has been fairly good. However, the present organization will not meet future requirements for standardization and documentation of quality. Currently a national standard for infection control is being prepared. It consists of a main standard defining requirements for the management system and 12 subsidiary standards defining requirements for specific areas of infection control. Adoption of the standard will undoubtedly require additional resources for infection control at a local level, and some organizational changes may also be needed. Infection control should be maintained as an integrated part of clinical microbiology.

Cross Infection↗
PubMed2000

[Amebiasis].

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Animals↗
PubMed2000

[Cryptococcosis].

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Antifungal Agents↗
PubMed1999

[National surveillance of Helicobacter pylori eradication in Denmark. Results based on registration of 34.582 drug prescriptions].

We wanted to characterize the use of H. pylori eradication therapy in Denmark (inhabitants 5,227,862). All H. pylori eradication treatments from a nation wide database covering all drug prescriptions in the period January 1994-June 1996 were identified. We found 28,784 out-patients having a prescription with drugs for H. pylori eradication, accounting for 34,582 prescriptions in total. The incidence of new consumers was 220 per 10(5) inhabitants per year, with a maximum at 70-79 years of age. Eighty-six percent of the patients had only one treatment course. Forty-five percent had an anti-ulcer drug prescribed 1-12 months after the H. pylori eradication therapy. Consumption of antibiotics used for H. pylori eradication accounted for 1.4% of the total consumption of antibiotics. In conclusion, the incidence of H. pylori eradication therapy was fairly stable but with changes in the pattern of drug regimens used. Anti-ulcer drugs were often given after H. pylori eradication therapy, suggesting an inappropriate use of eradication treatment.

Adult↗
PubMed1999

[Infections and cardiovascular disease].

Epidemiological studies indicate that respiratory tract and dental infections increase the risk of atherosclerotic cardiovascular disease. Several microorganisms have been claimed as clinically important, especially Chlamydia pneumoniae (Cp) and cytomegalovirus (CMV), Cp is frequently isolated from atherosclerotic plaques, and treatment with macrolide antibiotics may have a beneficial effect on the course of ischaemic heart disease. CMV seems to play a role in the development of coronary stenosis following coronary bypass surgery and heart transplantation. Likewise, inflammatory markers are associated with atherosclerotic cardiovascular disease. The pathogenetic role of microorganisms may be ascribed to the inflammatory response, which is elicited during infection. There is an urgent need for more documentation of the role of microorganisms in cardiovascular disease, and of the possible clinical effect of antibiotic treatment.

Anti-Bacterial Agents↗