Biomedical subjects

H J Kampke

Publications and source records attributed to H J Kampke.

3 recordsLinked to original sources

PubMed1978

[Karyovolumetric studies of postnatal differentiation of the amygdaloid complex in ovarectomized rats].

The caryovolumetrically definable prepubertal morphokinesis of the medial, cortical and basolateral amygdaloid nuclei in intact female rats (DOCKE and SMOLLICH 1978), which is probably related to the maturation of the ovulatory meachnisms, could not be demonstrated in females ovariectomized on the first day after birth and autopsied at 21, 26, 32, 36 or 39 days of age. Simultaneously, postnatal castration induced a specific stimulation of the metabolic activity of amygdaloid neurons. A distinct increase of cell nuclear volumes as compared to intact rats was recorded in the medial and basolateral amygdaloid nuclei and, to a lower degree, in the cortical amygdaloid nucleus. Neurons located in the parietal cortex did not respond in this way. The findings support the assumption that the mediocortical and basolateral amygdaloid regions belong to the cerebro-hypophyseo-gonadal axis and are involved in the differentiation and/or maturation of this axis.

Aging↗

PubMed1977

[Relationship between the limbic system and gonadal function. 2. Quantifiable prepuberal differentiation of medial cortical amygdaloid nuclei].

In juvenile female rats beteen the 21st and 26th days of age, the neurons of the medial and cortical amygdaloid nuclei undergo a highly significant karyovolumetrically measurable activation which, however, partially declines almost immediately. Such prepuberal variation of activity was found to be correlated with age-dependent effects of direct interventions with these nuclear regions upon the hypothalamy-pituitary-gonadal axis, e.g. implantation of oestradiol benzoate, stimulation or lesioning. This basically, is a quantitatibe-morphological confirmation of an assumption that had been derived earlier from experimental studies, according to which the mediocortical part of the amygdala undergoes in the prepuberal period a functional muteration or differentiation which is specific and related to puberty and gonadal functions (Döcke, 1976a, b; Döcke et al., 1976).

Aging↗

PubMed1976

[Relationship between the limbic system and gonadal function. Quantifiable morphokinesis of the medial amygdaloid nucleus with reference to the estrous cycle].

Karyovolumetric investigation showed that in rat the neurons of the limbic system which are associated with the Pars caudalis of the nucleus amygdaloideus medialis followed a morphokineses which was quantifiable in relation to the oestral cycle. The cell nuclei differed significantly in volume between cycle phases, which was interpreted as morphological correlation between variations in neuronal activity of metabolism. It was thought to be another point in support of the relationship between the amygdala and central-nervous structures of the cerebro-pituitary-gonadal axis.

Amygdala↗