Search PubMed⌕ Search

Biomedical subjects

H J Haug

Publications and source records attributed to H J Haug.

At least 37 records · Page 2Linked to original sources
PubMed1995

[Suicidal behavior of depressed patients at inpatient admission].

Early recognition of suicidal behavior is of extreme importance for avoidance of this cause of death. The risk of suicide attempts is particularly high in psychiatric illness, and among hospital in-patients especially in those with depression. Thus, the risk of suicide should be estimated in the first interview after admission to a psychiatric hospital. Our study analysed the routine documentation of such interviews on admission to the Psychiatrische Klinik der Freien Universität in Berlin: 41% of all depressive patients were suicidal. Suicidal and non-suicidal depressive patients could be differentiated by the following traits: suicidal patients were younger, had been younger at the initial onset of depressive illness, had made more suicide attempts in the past, and had a greater number of relatives who had committed suicide or made suicide attempts. They were more often single or divorced, and had fewer children of their own. Their psychopathology was characterized by a more strongly developed syndrome of depression, hostility and apathy. These findings point to a pattern of characteristics that are linked with suicidal behavior, which can be used to estimate the risk of suicide right at the beginning of a stay in hospital.

Adult↗
PubMed1994

Acute vs. chronic EEG effects in maprotiline- and in clomipramine-treated depressive inpatients and the prediction of therapeutic outcome.

Patients treated with the norepinephrine uptake inhibitor maprotiline showed an opposite tendency between acute and chronic effect of EEG. Whereas the acute effect indicated a decrease upon EEG vigilance, the chronic effect indicated an increase. Under clomipramine which acts upon different transmitter systems in a complex, up to now not fully understood way, acute and chronic EEG effects could not be differentiated.

Adult↗
PubMed1994

[Patient isolation in a psychiatric clinic].

Restrictive measures are widely used in psychiatric hospitals. But they are ill reputed. Little is known about them. This study is about the administration of isolation of mentally ill patients in a psychiatric hospital. 274 isolations of 100 patients within 11 months are recorded. Isolations concern 5% of the treated patients. That means two isolations on 1000 days of hospitalization. Mostly concerned are patients with schizophrenia or manic episodes. The most frequent reasons given were protection or irritation, danger for the patient or others but also molestation or provocation.

Adult↗
PubMed1992

Prediction of sleep deprivation outcome by diurnal variation of mood.

This study investigates whether response to total sleep deprivation in depressed patients may be predicted by the presence of diurnal variation of mood. Diurnal variation was measured with two different self-rating scales in 140 untreated depressed patients. Sleep deprivation responders manifest a higher percentage of diurnal variation than nonresponders, with a pattern of improved mood in the evening. Patients with marked diurnal variation respond better to sleep deprivation than those with little. The symptom of diurnal variation is a potential marker for a patient's likelihood to respond to different therapies.

Adult↗
PubMed1991

[Mood follow-up over 6 years in a patient with season-dependent form of depression (SAD)].

Since the first description of seasonal affective disorder (SAD), many international studies have confirmed the existence of this subgroup of depressive patients. Even though the diagnosis of SAD has been incorporated into the DSM-III-R classification system, many psychiatrists maintain a certain skepsis as to the existence of SAD as a separate sub-group of depression. The diagnostic issues are important because of the apparent specificity of treatment of SAD with bright light. Most diagnoses have relied on retrospective descriptions of the patients' depressive and healthy phases with respect to time of year. We present prospectively gathered weekly depression self-ratings in a SAD patient over a period of six years that may provide valid criteria for diagnostic purposes. This is a particularly exemplary case with implications for the relationship between light therapy and the course of depressive phases, the possible interaction of light treatment with lithium, the relationship between weight-changes and mood changes over the year and aspects of family loading of the illness.

Affective Symptoms↗
PubMed1990

Diurnal variations of mood in depressed patients in relation to severity of depression.

This study investigates the relationship between the severity of the depressive syndrome and the occurrence of diurnal mood variation. Several authors have proposed that diurnal variations of mood cease in the severest states of depression. By contrast, others suggest a rhythm-inducing effect of depression. We could not find any correlation between the severity of depression and various measures of diurnal mood variation in a group of 70 patients. These findings are discussed against the background of chronobiological hypotheses.

Adult↗
PubMed1989

Diurnal variations of mood in psychiatric patients of different nosological groups.

In order to investigate whether diurnal variations of mood (DV) are pathognomonic for the diagnosis of endogenous depression, 130 patients and 21 healthy control subjects were examined. The patients differed in the type of primary disease (neurotic, endogenous depression, depression in schizophrenia). All subjects recorded their subjective mood on the Visual Analogue Scale every morning and evening over a period of 3 weeks. In addition, they were classified by expert rating according to clinical criteria as belonging to one of the three different groups of rhythmic type: morning type, evening type, indifference type. The results reveal that DV occur frequently but that they are nonspecific. No correlation between nosological diagnosis and rhythmic type was found. It follows that DV, therefore, cannot improve sample homogeneity in studies on psychoactive drugs.

Affect↗
PubMed1988

Sleep deprivation and imipramine binding sites in depressed patients and healthy subjects.

The influence of sleep deprivation on 3H imipramine binding was investigated in blood platelets of 32 depressed patients and 15 healthy subjects. The effect of sleep deprivation was not statistically different in either group. Changes of Bmax associated with sleep deprivation were compensated for by reciprocal changes of Kd in the group of patients, suggesting altered regulatory mechanisms. A comparison of binding characteristics of responders and nonresponders to sleep deprivation revealed no difference between groups. If the patients were divided by a biological criterion (number of binding sites), a prediction of clinical response to sleep deprivation was possible.

Adult↗