Biomedical subjects

H J Drescher

Publications and source records attributed to H J Drescher.

4 recordsLinked to original sources

PubMed2005

High-density QCD and cosmic-ray air showers.

We discuss particle production in the high-energy, small-x limit of QCD where the gluon density of hadrons is expected to become nonperturbatively large. Strong modifications of the phase-space distribution of produced particles as compared to leading-twist models are predicted, which reflect in the properties of cosmic-ray induced air showers in the atmosphere. Assuming hadronic primaries, our results suggest a light composition near Greisen-Zatsepin-Kuzmin cutoff energies. We also show that cosmic-ray data are sensitive to various QCD evolution scenarios for the rate of increase of the gluon density at small x, such as fixed-coupling and running-coupling Balitsky-Fadin-Kuraev-Lipatov evolution. There are clear indications for a slower growth of the gluon density as compared to RHIC and HERA, due, e.g., to running-coupling effects.

Journal Article↗

PubMed2004

Novel mechanism of H0 dibaryon production in proton-proton interactions from parton-based Gribov-Regge theory.

A novel mechanism of H0 and strangelet production in hadronic interactions within the Gribov-Regge approach is presented. In this approach the H0 is produced by the same mechanism as usual hadrons, namely, by disintegration of the remnant formed by the exchange of pomerons between the two protons. Rapidity and transverse momentum spectra of the observed hadrons are well described in this approach. In contrast to traditional distillation approaches, here the production of multiple (strange) quark bags does not require large baryon densities or a quark gluon plasma. We calculate the rapidity and transverse momentum distributions as well as the 4pi multiplicity of the H0 for sqrt[s]=17 GeV (Super Proton Synchrotron) and 200 GeV (Relativistic Heavy Ion Collider). In both cases the H0, if it exists, should be observable by the present experiments.

Journal Article↗

PubMed2001

Self-consistency requirement in high-energy nuclear scattering.

Practically all serious calculations of exclusive particle production in ultrarelativistic nuclear or hadronic interactions are performed in the framework of Gribov-Regge theory or the eikonalized parton model scheme. It is the purpose of this paper to point out serious inconsistencies in the above-mentioned approaches. We demonstrate that requiring theoretical self-consistency reduces the freedom in modeling high-energy nuclear scattering enormously, and we introduce a fully self-consistent formulation of the multiple-scattering scheme in the framework of a Gribov-Regge--type effective theory. In addition, we develop new computational techniques which allow for the first time a satisfactory solution of the problem in the sense that calculations of observable quantities can be done strictly within a self-consistent formalism.

Journal Article↗

PubMed1983

[Influenza].

Influenza is the last great uncontrolled plague of mankind. Pandemics and epidemics occur at regular time intervals. The influenza viruses are divided into the types A, B and C and show unique variability of their surface antigens (hemagglutinin and neuraminidase). Influenza viruses of type A show the largest degree of antigenic variation which, in turn, resulted in the definition of a number of subtypes, each comprising many strains. By comparison, influenza viruses of types B and C exhibit much less variation of their surface antigens. As a consequence, no subtypes but many different strains have been recognized. The degree of antigenic variation correlates with the epidemiologic significance of the virus types, type A being the most and type C the least important. Two different kinds of antigenic variation have been recognized: In the case of minor variation of one or both surface antigens, the term "antigenic drift" is employed. Antigenic drift occurs with all three types of virus, it is caused by point mutations which increase the chance of survival of mutants in the diseased host. In addition, influenza A viruses show sudden and complete changes of their surface antigens in regular time intervals, resulting in the appearance of new subtypes. This event is called "antigenic shift". The mechanisms responsible for antigenic shift are poorly understood, only. In addition to the recycling of preceding subtypes, reassortment resulting from double infection of cells with strains of human and animal origin are considered possible explanations. By use of modern DNA recombinant technology, the base sequences of a series of virus genes and, as a consequence, the amino acid sequence of the corresponding antigens have been determined. By means of monoclonal antibodies, the antigenic structure of many influenza antigens has been further elucidated. It can be expected that further research on the molecular basis of antigenic variation could finally result in an understanding of the causal mechanisms. It is an outstanding feature of the epidemiology of influenza A viruses that a family of related strains prevails for a certain period of time and disappears abruptly as a new subtype emerges.(ABSTRACT TRUNCATED AT 400 WORDS)

Antigens, Surface↗