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Biomedical subjects

H J Chun

Publications and source records attributed to H J Chun.

41 records · Page 3Linked to original sources

[Some tentative cases of the holistic approach to health care].

Some observers have insisted that modern medicine should be restored to the holistic nature in the face of the limitations of the current mechanistic modern medicine. Four medical doctors trained in modern medicine, Simonton, Chopra, Kohda and Takeguma are showing the creative models of medicine based on the holistic philosophies and methodologies. It will be meaningful to investigate what the sociocultural backgrounds of their thinkings and practices are, and how much these are socially acceptable and useful.

History, 20th Century↗

New approach to radial expansive force measurement of self expandable esophageal metal stents.

The accurate measurement of radial expansive force is crucial for optimal design and implantation of self expandable esophageal metal stents. In the present study, a new method of measurement under experimental conditions simulating actual stent implantation has been developed. This method offers precise and reproducible measurements and can be applied to a wide variety of stent types. In particular, the method enables one to measure expansive pressure as well as the true radial expansive force up to the radial compression ratio of 72%, covering the range of compression often encountered in a partially obstructed lumen. The test results for various kinds of metal stents are presented and compared. Based on these results, three important points of observation critical in explaining and predicting the expansion characteristics of stents have been reported. Further understanding and characterization of these findings will be necessary for developing new stents with outstanding clinical efficacy.

Compliance↗

Gastrointestinal leiomyoma and leiomyosarcoma: CT differentiation.

PURPOSE: Our goal was to evaluate CT efficacy in differentiating gastrointestinal leiomyoma and leiomyosarcoma. METHOD: We retrospectively reviewed CT scans of 45 patients (21 men, 24 women, mean age 55 years) with surgically proven gastrointestinal leiomyomas (n = 21) and leiomyosarcomas (n = 24) with respect to size, contour, enhancing pattern, mesenteric fat infiltration, calcification, ulceration, regional lymphadenopathy, direct invasion, distant metastasis, and growth pattern after visual inspection by two radiologists in agreement. On the basis of these CT features, subjective diagnosis was also categorized into three groups (Group I: probably benign, Group II: probably malignant, Group III: diagnostic malignant). The results were compared with the final histopathologic diagnosis. RESULTS: In addition to the features of direct invasion and distant metastasis suggesting diagnostic malignancy, the CT features favoring malignancy with statistical significance included larger size (> 5 cm), lobulated contour, heterogeneous enhancement, mesenteric fat infiltration, ulceration, regional lymphadenopathy, and exophytic growth pattern (p < 0.005). However, calcification was not significant in differentiating the two entities (p = 0.25163). A subjective analysis revealed 89% sensitivity, 85% specificity, and 87% accuracy for diagnosis of leiomyosarcoma. CONCLUSION: CT features are useful in differentiating leiomyoma and leiomyosarcoma in gastrointestinal tract.

Adult↗