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Biomedical subjects

H J Busse

Publications and source records attributed to H J Busse.

At least 55 records · Page 3Linked to original sources
PubMed1982

[Acetaldehyde-induced leukocyte migration inhibition in alcoholic liver diseases].

Acetaldehyde in non-toxic doses (15.6 micrograms per start) causes in the inhibition test of the migration of leucocytes an inhibition of the migration in 6/13 of the patients with alcoholic hepatitis, a stimulation of the migration in 6/11 of alcohol cirrhoses. Healthy (n = 16) persons, patients with alcoholic fatty degeneration of the liver (n = 3) as well as non-alcoholic liver diseases (chronic persisting hepatitis, n = 11; chronic active hepatitis, n = 8, cirrhosis, n = 7) did not show this cellular immune reagibility. The inhibition of the migration and the stimulation of the migration, respectively, might develop by hapten autoantigen complexes (altered cytoskeleton?) with release of the factors of inhibition of migration and stimulation of migration, in which case the role of a hapten belongs to acetaldehyde. The results of the tests did not correlate with functional and histological findings of the liver, with the actual consumption of alcohol and also not with haptoglobin phaenotypes. When it is postulated that by acetaldehyde also the release of further lymphokines is mediated, origin and progression of alcoholic hepatitis and alcoholic cirrhosis might be explained immunopathogenetically.

Acetaldehyde↗
PubMed1982

[Cell-mediated immune reactivity in skin tests in chronic liver diseases].

For the judgment of cell-mediated immune reactivity in patients with chronic liver diseases in comparison to healthy test persons tests of the skin were performed by means of the neoantigen DNCB and the recall antigens tuberculin and streptokinase. Depending on the degree of severity of the hepatopathies the intensity of reaction decreased in the DNCB-test. There were no relations to the etiopathogenetic factors of the liver diseases. The results speak for the fact that the disturbed immune reactivity to DNCB is to be regarded as sequela of the disease. The anamnestic immune response controlled by means of the two recall antigens did not show any quantifiable differences to the reference collective in the chronic hepatopathies. It is concluded that the findings of skin tests are not able to contribute to the indication for immunosuppressive or immune modulating therapeutic methods.

Chronic Disease↗
PubMed1982

[The value of ultrasound tomography in the differential diagnosis of cholestasis - a review].

In early use the sonography may facilitate and accelerate the differential diagnosis of the cholostasis. In parenchymal hepatic icterus frequently pathologic changes of the liver may be proved sonographically. the typical findings of dilated and thus sonographically demonstrable intra- and extrahepatic biliary ducts speak for obstructive jaundice. Characteristic constellations of dilated segments of the bile duct allow conclusions to the localisation of the occlusion. Changes which cannot be explained by sonography are cause for further examinations.

Cholestasis, Intrahepatic↗
PubMed1982

[Ultrasound determination of size and calcium content of gallstones].

In a prospective study, ultrasound examinations of the gallbladder as well as cholecystocholangiography were carried out in 77 patients with solitary stones and the ultrasound stone symptoms were compared with the x-ray findings. The ultrasound stone reflex as well as the wideness of the sonic-shadow correlated significantly with the size of the stones. The stone size can be approximately calculated from the wideness of the sonic shadow. On the other hand dependence of the ultrasound stone symptoms and the radiographic defined calcium was not evident. While the stone size can be sonographically defined, the indentification of calcium in gallstones continues to remain a domain of radiographic methods.

Calcium↗
PubMed1981

[Contribution of sonography to the diagnosis of colonic tumors].

Though also in future roentgenological and endoscopic bioptic techniques determined the practice in the diagnostics of tumours of the large intestine the routine use of sonography may shorten the way to diagnosis in numerous cases when the so-called cocard phenomenon (= infiltrated intestinal wall) is proved. On the other hand, the cocard phenomenon may serve as an additional criterion of malignity when a roentgenological and/or endoscopic suspicion of malignoma at first cannot be confirmed bioptico-histologically.

Colonic Neoplasms↗
PubMed1979

[Use of B-sonography in the diagnosis of liver diseases].

The criteria important for the sonographic judgment of the liver and the value of the sonography in the strategy of the diagnostics of liver diseases are described. Since none of the symptoms mentioned, such as size of the liver, ventral contour, lower margin of the liver, demarcability, sound conduction as well size, density and distribution of the structural reflexes, is typical for a certain disease, an approximate diagnosis or the exclusion of certain diseases is a possible only taking into consideration several symptoms and also extrahepatic, sonographically probable ones. On account of the simplicity and of the undangerousness of the examination it is obvious to use the sonography immediately after the examination and thus to organize the selection of further diagnostic measures more rational.

Cysts↗
PubMed1979

[Possibilities of ultrasonic diagnosis of thyroid and gastrointestinal diseases].

Issuing from the physical principles of the ultrasound technique and the explanation of the different investigation methods, the possibilities of the ultrasonic diagnosis are demonstrated on own results in 1,166 cases of struma nodosa and 154 palpatorically and radiologically, respectively, localised enlargements of the organs or demands of space in the abdominal region. The establishment of 46 cysts in 357 scintigraphically warm nodes of the thyroid gland allows the conclusion that a relatively high percentage of the warm nodes contains solid cold regions. In several cases the ultrasonic diagnosis makes a clear diagnosis, in other cases it is an important supplementation to the other diagnostic possibilities. The A-picture-apparatuses produced in the GDR are suitable for the differential diagnosis of palpatorically or radiologically localised enlargements of the organs or space demands. In diffuse diseases of the organs and for the search of disturbances in extended regions B-picture-apparatuses with improved resolving power are necessary.

Bile Ducts↗
PubMed1978

[Value of sonography in the differential diagnosis of icterus].

In early use the sonography may facilitate and accelerate the differential diagnosis of the jaundice. In parenchymal hepatic icterus frequently pathologic changes of the liver may be proved sonographically. The typical findings of dilated and thus sonographically demonstrable intra- and extrahepatic biliary ducts speak for obstructive jaundice. Characteristic constellations of dilated segments of the bile duct allow conclusions to the localisation of the occlusion. Changes which cannot be explained by sonography are a cause for further examinations.

Diagnosis, Differential↗