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Biomedical subjects

H J Brody

Publications and source records attributed to H J Brody.

28 records · Page 2Linked to original sources

Variations and comparisons in medium-depth chemical peeling.

Two effective methods in chemical peeling, solid carbon dioxide plus trichloroacetic acid and Jessner's solution plus trichloroacetic acid, were compared clinically with photographs and histologically with serial biopsies. Carbon dioxide produced a deeper wound than Jessner's solution, and CO2 + TCA was slightly deeper than Jessner's + TCA but was probably not significantly deeper from a clinical standpoint except in correcting scarring. Triple consecutive applications of TCA can substantially increase wound depth with both combination peels.

Administration, Topical↗

Complications of chemical peeling.

In spite of controlled wounding with chemical peeling agents, complications may occur, resulting in patient and physician dissatisfaction. Precautions and factors causing these complications are examined, and relative contraindications to chemical peeling are discussed.

Chemexfoliation↗

Medium-depth chemical peeling of the skin: a variation of superficial chemosurgery.

Medium-depth chemical peeling of the skin is an intermediate procedure between superficial trichloroacetic acid application and deep phenolic cauterant application. Combining solid carbon dioxide with trichloroacetic acid promotes both epidermal and dermal regeneration. The technique for treatment of actinic degeneration, acne scarring, rhytids, and pigmentary aberrations is presented.

Adult↗

Black tongue secondary to methyldopa therapy.

A case of black tongue associated with methyldopa administration is reported. The symptoms disappeared when the medication was discontinued. The possible mechanism is discussed.

Humans↗

Carcinoid in an umbilical nodule.

An umbilical nodule may be an early or late sign of metastasis from an internal location. To our knowledge, we are reporting the first case of carcinoid occuring as an umbilical mass. The occurrence in our patient of idiopathic hyperparathyroidism, diabetes mellitus, and carcinoid suggests the diagnosis of multiple endocrine adenomatosis, type I, which may result from a developmental defect in the amine and amine precursor uptake and decarboxylation cell system.

Abdominal Neoplasms↗

Spindle cell lipoma. An unusual dermatologic presentation.

A 30-year-old woman had nontender subcutaneous mass over the left temple that histologically demonstrated a mixed pattern of mature lipocytes and spindle cells, many in a palisading and fascicular pattern, separated by fibrous trabeculations. No cellular atypia or increased mitotic activity was seen, and a predominance of mast cells was noted. This case illustrates the spindle cell lipoma, a benign variant of lipoma that has been confused in the past with both malignant spindle cell and lipocytic tumors. Our case, although atypical in sex, age, and location, serves to identify this entity in the dermatologic literature.

Adult↗

Photolocalized tinea facialis.

The case of a 34-year-old white woman with tinea facialis that persisted for nine months prior to diagnosis is presented. The confluent plaquelike erythematous eruption of the face with eyelid lichenification that flared outdoors was thought to represent polymorphic light eruption and was refractory to antibiotics, corticosteroids (topical and systemic), and antimalarials. A KOH preparation was positive when the dermatosis spilled onto the mandibular region, and restaining of the initial skin biopsy revealed fungal hyphae. Complete resolution was accomplished with griseofulvin and MicTin. Tinea cab be added to the list of infectious agents that have a photosensitivity component. The fungus possibly "photolocalizes" to sun-damaged areas, ie, areas of increased capillary permeability. This case illustrates the importance of including tinea in considering diagnoses of sun-exposed lesions of the face.

Administration, Topical↗