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Biomedical subjects

H Itaya

Publications and source records attributed to H Itaya.

At least 37 records · Page 2Linked to original sources

Application of Duhamel's operation for the surgical treatment of rectal cancer.

Several sphincter-preserving procedures for surgical removal of cancer at the upper or middle part of the rectum often cause disturbances of the ano-rectal and bladder functions. To preserve these functions it is important to minimize the damage to the anal sphincter as well as to the pervic nerves and to preserve the rectal mucous membrane as much as possible. Duhamel's procedure was employed with very satisfactory results.

Adult↗

Effects of anticancer agents of the intestinal epithelium. A morphologic study.

In order to make clear the pathophysiology of digestive symptoms which are caused with anticancer agents, three anticancer agents, i.e., mitomycin C, 5-FU and cytosine arabinoside were administered pre-operatively, and the ultrastructure of the intestinal epithelium, especially that of absorptive cells, were studied on the specimens collected intra-operatively. In view of the finding that severe degeneration occurred inside cytoplasms, chiefly their nuclei, it was surmised that the biosynthesis and supply of proteins such as digestive enzymes were not amply carried on; hence, the chemotherapy could give rise to severe digestion and absorption disorders. It appeared necessary to further study the dosage and dosage schedule of the anticancer agents, along with the necessity for taking ample care of patients presenting such disorders.

Antineoplastic Agents↗