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Biomedical subjects

H Israel

Publications and source records attributed to H Israel.

8 recordsLinked to original sources
PubMed1992

Gingival lesions in lipoid proteinosis.

Lipoid proteinosis is a rare heritable disease of the skin and mucous membranes characterized by subepithelial deposits of hyaline material. The morbid factors include disfiguring papulo-nodular lesions particularly of exposed skin, hoarseness of voice due to vocal cord infiltration, nodular deformation of the eyelids, and board-like rigidity of the tongue. Infiltration of the gingiva is usually unreported, and when mentioned has been equivocally related to the overall disease process. This patient demonstrates striking ulceration and hypertrophy with histologic evidence of heavy deposition of amorphous material confirming a gingival component to the lipoid proteinosis entity.

Adolescent↗
PubMed1979

Basioccipital clefts.

Two cases of rare basioccipital clefting are reported. In one patient, 10-year follow-up indicates that the radiologic appearance of the clefts does not change with time. Findings in the other case indicate that additional anomalies may occur in adjacent bone structures developing in sequence. A review of the embryological development and discussion of the radiological findings are presented.

Adolescent↗
PubMed1979

Suppressor cell function in sarcoidosis.

We investigated the role of suppressor cells in the depressed cellular immunity of patients with sarcoidosis. The mean response in 16 patients with active sarcoidosis to three concentrations of phytohemagglutinin was significantly (P less than 0.01) less than control values. Passage of the cells over glass wool resulted in a 116% increase in response to phytohemagglutinin in patients and a 39% decrease in control subjects. Addition of indomethacin to phytohemagglutinin cultures increased the response of cells in patients with sarcoidosis by 192% +/- 32% versus a 112% +/- 18%-increase for control subjects (mean +/- SEM, P less than 0.05). Patients had an increased percentage of monocytes in peripheral blood mononuclear cell preparations, and the percent monocytes correlated with the percent increase in phytohemagglutinin response after glass wool passage (r = 0.62, P less than 0.05). Thus, several factors contribute to the depressed phytohemagglutinin response in sarcoidosis patients: an increased suppression by the prostaglandin-producing suppressor cell, an increased percentage of monocytes, and an as yet undefined factor.

Adult↗
PubMed1977

The dichotomous pattern of craniofacial expansion during aging.

The craniofacial skeleton expands during adult life and previous investigations have demonstrated non-uniformity in continuing growth. This report confirms the fact that sella turcica, frontal sinus and the skull tables remodel at a rate per unit time which is twice the amount of the anterios and posterior skull diameter. The dual enlargement pattern occurs in both male and females and has been observed longitudinally from the third through the eighth decades of life. Though associations in the continuing growth process of separate anatomical parts throughout the human skeleton remain obscure, the degree to which components vary within the craniofacial system is now clearly evident.

Adult↗