The structure of stenine, a new alkaloid occurring in Stemona tuberosa.
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Biomedical subjects
Publications and source records attributed to H Irie.
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MR images of the liver in 13 patients with surgically proven intrahepatic cholangiocarcinoma were reviewed retrospectively and correlated to the histologic analysis of surgical specimens. We paid special attention to the peripheral liver tissue with ductal dilation but without tumorous involvement. High signal intensity was observed in the hepatic parenchyma with ductal dilation on T1-weighted spin-echo images (8 of 12) and spoiled gradient-recalled echo images (seven of seven), as compared with the contralateral hepatic lobe without duct dilation. The high signal intensity was not suppressed with fat saturation and showed enhancement after administration of contrast (11 of 12). Concurrent portal venous obstruction did not have significant effect on these findings (P < .05). Correlation with pathologic specimens suggested that this enhancement was associated with periportal fibrosis. The etiology of the high signal intensity on unenhanced spin echo or gradient-recalled T1-weighted image remains unclear. Radiologists should recognize these findings and should distinguish these from tumor involvement or the arterial buffer response caused by portal venous obstruction.
Forty-nine pathologically proven gallbladder lesions were evaluated in 45 patients using dynamic MRI with a spoiled gradient pulse sequence (SPGR), to access the ability of this technique to differentiate benign from malignant gallbladder lesions. The studies were reviewed retrospectively. Signal intensity of the lesions were measured. Twenty-one malignant and 28 benign lesions were classified into three categories: polypoid, diffuse wall thickening, and exophytic. Early and delayed enhancement patterns were evaluated. For the polypoid masses, malignant lesions (n = 9) demonstrated early and prolonged enhancements, whereas benign lesions (n = 14) had early enhancement with subsequent washout (P < .05). For diffuse gallbladder wall thickening, malignant lesions (n = 6) demonstrated early and prolonged enhancement and benign lesions (n = 14) showed relatively slow, prolonged enhancement (P < .05). The exophytic masses (n = 6) all were malignant and demonstrated early and prolonged enhancement. Dynamic MRI can help differentiate benign from malignant gallbladder lesions.
A 51-year-old man suffered from bleeding esophageal varices. He had undergone partial gastrectomy for gastric cancer 1 year before. An extrahepatic arterioportal fistula and resultant portal hypertension were found. We successfully performed transarterial embolization of the fistula using stainless steel coils. Portal hypertension improved dramatically.
BACKGROUND: We investigated whether diffusion-weighted echo-planar magnetic resonance (MR) imaging can help differentiate intraductal mucin-producing tumors of the pancreas from other cystic lesions. METHODS: Diffusion-weighted echo-planar MR imaging was performed in patients with mucin-producing tumors (n = 19), pseudocysts (n = 9), chronic pancreatitis with diffuse main pancreatic dilatation (n = 5), and serous cystadenomas (n = 2). Images were obtained with diffusion sensitizing gradients of 30, 300, and 900 s/mm2. The apparent diffusion coefficient (ADC) was calculated. RESULTS: The mean (+/- standard deviation) ADCs of mucin-producing tumors (2.8 x 10(-3) mm2/s +/- 1.0 x 10(-3)), pseudocysts (2.9 x 10(-3) mm2/s +/- 1.2 x 10(-3)), dilated main pancreatic duct in chronic pancreatitis (3.3 x 10(-3) mm2/s +/- 1.2 x 10(-3)), serous cystadenomas (2.9 x 10(-3) and 2.6 x 10(-3) mm2/s), and cerebrospinal fluid (3.5 x 10A(-3) mm2/s +/- 1.1 x 10(-3)) were not statistically different. CONCLUSION: It is difficult to differentiate between mucin-producing tumors and other cystic lesions by ADC measurements when using diffusion-weighted echo-planar MR imaging.
Torsion of the gallbladder (GB) is a rare, acute abdominal condition. The treatment of choice is cholecystectomy. Even with recent advances in radiologic imaging modalities, it is difficult to make a correct preoperative diagnosis of GB torsion. We report a case of GB torsion with a retrospective review of the radiologic findings of magnetic resonance imaging, computed tomography, and ultrasonography. Those findings were compared with the histopathologic findings of the surgical specimen. The radiologic findings in our case were useful for making a preoperative diagnosis of GB torsion. We postulate the characteristic magnetic resonance findings and discuss discrepancies in the evaluations of the GB wall.
A case with liver metastasis from papillary renal cell carcinoma (RCC) is presented, in which intratumoral fat was detected on dual-echo chemical shift magnetic resonance imaging (MRI). The preoperative chemical shift MR image of the primary RCC also suggested the presence of intratumoral fat. Liver metastasis from fat-containing RCC should be included in the differential diagnosis of fat-containing liver masses as observed on chemical shift MRI.