A neonate with absent pulmonary valve syndrome was examined by means of echocardiography and magnetic resonance imaging (MRI). MRI provided an excellent evaluation of the intracardial morphology, vessel anatomy, mediastinal structures, and shunt flow; and it was superior to echocardiography for detection of aortopulmonary collaterals and vessel abnormalities. This case report of an uncommon cardiac abnormality confirms that MRI is a useful complementary modality to echocardiography in neonates and is recommended for problems with central pulmonary vessels and their relation to tracheobronchial structures.

Echocardiography↗

PubMedDate not supplied

Contrast MRI in multiple endocrine neoplasia type 1 (MEN) associated with renal cell carcinoma.

The radiologic work-up of a patient with multiple endocrine neoplasia type 1 (MEN 1) syndrome and multiple endocrine nodules, with coincidental renal cell carcinoma, is described. Parathyroid adenoma was differentiated from multiple thyroid nodules by gadolinium-enhanced MRI. Adrenal enlargement due to a nonfunctioning adenoma and a renal cell carcinoma next to a simple renal cortical cyst were identified by typical signal intensities on T1- (pre- and post-Gd-DPTA) and T2-weighted images. Insulinoma was visualized only retrospectively.

Adenoma↗

PubMedDate not supplied

[Imaging procedures in diagnosis of bone tumor].

The historical development of the various imaging procedures for diagnosis, differential diagnosis and for the effect of chemotherapy of malignant bone lesions are discussed. The present status of imaging including MRT has been defined.

Bone Neoplasms↗

PubMedDate not supplied

[CT in the surgical planning in tumorous processes of the sacrum].

The value of CT in the preoperative management of tumors of the sacrum is demonstrated. Essential informations for treatment planning are: involved sacral segment, infiltration of sacral foramina and nerve roots, involvement of the sacroiliac joints, ingression of the lumbar spine, infiltration of the pelvic organs and vessels, sciatic nerve and the dorsal soft tissues. In order to prove the competence of the CT in answering these questions we evaluated the CT-examinations of 30 pat. with 14 primary tumors, 9 metastatic tumors and 7 tumors involving secondary the sacrum. The CT findings were correlated with clinical symptoms and surgical reports in 11 pat., with clinical symptoms alone in 19 pat. There was good correlation in the criterias: location and number of involved segments (8/11, 17/19), infiltr. of SI-joints (11/11), infiltr. of lumbar spine (9/11, 18/19), and infiltr. of pelvic organs (10/11), worse correlation in the criterias: nerve root-involvement (2/11, 3/19), and sciatic nerve-infiltr. (7/11, 15/19). Our conclusions are that CT gives helpful preoperative informations deciding about extent of surgical procedure, and surgical approach. The major problem, however, consist in diagnosis of nerve root and sciatic nerve involvement, therefore in poor prediction of postoperative conservation of neural functions. The knowledge of CT-anatomy of sacrum- and important condition for correct segment-location of the tumor is refreshed by outlines of characteristic segmental CT-sections of the sacrum.

Adult↗

PubMedDate not supplied

MRI in the diagnosis of primary lymphoma of bone: correlation with histopathology.

Seven patients with primary non-Hodgkin lymphoma of the skeleton were examined with MRI. The results were compared to "small cell" primary malignant bone tumors. The latter showed marked hyperintensity on SE T2-weighted images; in contrast, the lymphomas appeared as inhomogeneous lesions of low signal intensity on T2-weighted images. Histologic examination with silver stains of specimens of these lesions revealed a high content of fibrous tissue, which could explain the signal behavior on MR. All seven lymphomas were located in the epiphysis or metaphysis of the appendicular skeleton; intraarticular tumor growth was demonstrated in five cases.

Adolescent↗

PubMedDate not supplied

MR contrast arthrography (MRA) in osteochondrosis dissecans.

Osteochondrosis dissecans (OCD) is a lesion that characteristically affects the articular cartilage and subchondral bone with the potential of fragmentation and separation. Exact assessment of cartilaginous and subchondral bony changes is mandatory for the planning of adequate treatment. Therefore, we examined 25 knees using spin echo (SE) and gradient echo (GE) sequences on a 1.5 T superconducting unit prior to and following intraarticular administration of 40 ml of a 2 mmol/L Gd-DTPA solution (MR arthrography). For evaluation (staging) a modified Clanton and DeLee scheme was employed. Verification by arthroscopy or arthrotomy was available in 24 cases. A correct diagnosis of OCD with regard to its type prior to intraarticular injection of Gd-DTPA was possible in 39.3% using T1-weighted SE sequences and in 57.4% on GE sequences. After intraarticular administration of Gd-DTPA, the rate of correct diagnoses improved to 92.9% on T1-weighted SE sequences and 100% on GE sequences. Magnetic resonance arthrography appears to be helpful for the exact assessment of the articular cartilage overlying OCD lesions as well as for the differentiation between partial and complete separation of cartilaginous or osteocartilaginous fragmentations.

Adolescent↗

PubMedDate not supplied

Postcontrast MR arthrography in assessment of cartilage lesions.

OBJECTIVE: Although MR has been proven effective in evaluating many components of the musculoskeletal system, including ligaments, fibrocartilage, muscle, and bone marrow, its role in the evaluation of articular cartilage remains controversial. Recent studies have demonstrated that intraarticular injection of Gd-DTPA [MR arthrography (MRA)] improves the detection of cartilage abnormalities in cadaveric specimens. The aim of this study was to determine the efficacy of MRA for the detection of naturally occurring cartilage lesions in a clinical population. MATERIALS AND METHODS: Sixty knees of 58 patients were studied with a three-dimensional (3D) T2*-weighted GE sequence (FISP) both before and after and a T1-weighted (T1W) SE sequence after the intraarticular injection of a 2 mmol/L Gd-DTPA solution. All knees subsequently underwent arthroscopy or arthrotomy. RESULTS: The MRA sequences performed significantly better (kappa = 0.85) than the routine FISP sequences (kappa = 0.39) in both the detection and the staging of cartilage abnormalities. The MRA FISP sequence (kappa = 0.91) performed slightly better than the MRA T1W sequence (kappa = 0.85), but there was no statistically significant difference between the two sequences. No complications from the intraarticular injection of contrast material occurred. CONCLUSION: Therefore, MRA appears to be an effective and safe method for the evaluation of articular cartilage abnormalities.

Adolescent↗