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Biomedical subjects

H Ikram

Publications and source records attributed to H Ikram.

At least 217 records · Page 12Linked to original sources

Clinical evaluation of perhexiline maleate in patients with angina pectoris.

This paper reports a double-blind trial of a new antianginal drug, perhexiline. Fifty-five patients suffering from angina pectoris were studied for periods of 12 or 24 weeks in a cross-over comparison against a placebo in four centres in the United Kingdom and Ireland. Perhexiline was effective in most patients as judged by reducing the number of anginal attacks in 84% and the consumption of glyceryl trinitrate tablets in 64%. The major side effect, dizziness, noted in one-third of the patients, may be dose/body-weight related. Perhexiline is a valuable new agent for the treatment of patients with angina, especially those who do not respond to other antianginal agents.

Adult↗

Scleroedema of Buschke. An uncommon cause of cardiomyopathy.

A case of scleroedema of Buschke involving skin and myocardium in a 69-year old woman is described. Widespread electrocardiographic abnormalities were present at the height of the disease, which improved over 18 months as the mucopolysaccharide infiltration of the skin cleared.

Aged↗