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H I Wildschut

Publications and source records attributed to H I Wildschut.

At least 19 recordsLinked to original sources

Are sociodemographic factors predictive of preterm birth? A reappraisal of the 1958 British Perinatal Mortality Survey.

OBJECTIVE: Reassessment of the predictive value of sociodemographic factors on preterm birth. DESIGN: Population-based case-control study. SETTING: England, Wales and Scotland. SAMPLE: The study sample consisted of 5630 primiparous and 9538 multiparous women who were delivered during the first week of March 1958 in Britain. Multiple births were excluded. METHOD: Factors potentially predictive of preterm birth were assessed for primiparous and multiparous women separately, using the split-sample cross-validation technique. MAIN OUTCOME MEASURE: Preterm birth, defined as birth occurring before 259 days of gestation. RESULTS: Preterm birth rates for primiparous and multiparous women were 54 and 53 per 1000 births, respectively. In primiparous women low maternal age (under 20 years) was the only sociodemographic variable that was predictive of preterm birth (P = 0.01). However, only 10.7% of preterm birth among primiparous women was associated with low maternal age. In multiparous women, using univariable analysis, employment status was statistically significantly associated with preterm birth. This association disappeared when employment status was adjusted for by other variables in the model. Social class was not predictive of preterm birth in either primiparous or multiparous women. CONCLUSION: From the results of this study it is concluded that sociodemographic factors do not have a substantial impact on the risk of preterm birth. It seems unlikely that preventative measures aimed at social-demographic adversity will reduce preterm birth rates.

Case-Control Studies

Planned abdominal compared with planned vaginal birth in triplet pregnancies.

OBJECTIVE: To compare a policy of planned abdominal delivery with a policy of planned vaginal delivery in triplet pregnancies. DESIGN: Retrospective study. SETTING: Two Dutch university hospitals, each having a different approach to the planned mode of delivery in triplet gestations. SUBJECTS: Thirty women giving birth to triplets in the hospital in Leiden, who favoured planned abdominal delivery, compared with 39 from the Medical Centre in Amsterdam who favoured vaginal delivery. MAIN OUTCOME MEASURES: Perinatal mortality and early neonatal complications. RESULTS: Both centres were equally successful in achieving their planned policies: in Leiden 80% of women were delivered by caesarean section but in Amsterdam 87% of women were delivered vaginally. Compared with vaginal delivery, planned abdominal delivery was associated with a significantly higher perinatal mortality rate (P = 0.02), primarily due to respiratory distress syndrome, and a higher recorded neonatal complication rate (P = 0.03), especially sepsis, respiratory distress syndrome, and necrotising enterocolitis. CONCLUSIONS: A policy of planned abdominal delivery in triplets is not superior to a policy of planned vaginal delivery in terms of fetal and early neonatal outcome.

Adult

[Ambulance transportation time of obstetrical patients].

OBJECTIVE: To examine the time the ambulance needs to transfer women in labour, or immediately after delivery, from home to hospital. DESIGN: Descriptive. SETTING: Amsterdam, the Netherlands. METHOD: Ambulance data from the 'Centrale Post Ambulancevervoer', region Amsterdam, were analysed over a period of one year (1992/1993). RESULTS: Of the 287 women who were transported during labour with urgency code A1 (critical condition) 244 (85%) arrived within 0.5 h in hospital, of 124 who were not in a critical condition (urgency code A2) 66 (53%) (chi 2 = 47.2; p < 0.00001). The average duration for A1 transport of the 51 women who were transferred immediately after delivery, was 32 min. Of those who went by ambulance with urgency code A2 (n = 86) the average duration was 37 min. For A1 transport the ambulance is legally bound to arrive within 15 min. In 7 women (2%) the transport time exceeded 15 min. This was not associated with time of day or distance to hospital. Factors that influenced the duration of ambulance transport included the allocated emergency code, the timing of transport in relation to parturition and the distance between the home and hospital. CONCLUSION: In the municipality of Amsterdam transportation by ambulance of obstetrical patients from home to hospital can in most cases be realised within 0.5 h. The difference in average total time between A1 and A2 transport during labour is only 7 min, but the likelihood of arriving at the hospital within 0.5 h is much greater with A1 than with A2 transport.

Adult

Vasectomy and the risk of prostate cancer.

Even if there is a weak association between vasectomy and subsequent prostate cancer, we believe that large-scale studies on this question should be of low priority in developing countries where vasectomy is widely practised and where the incidence of prostate cancer is low. Arguments to justify this point of view are presented.

Developing Countries

Pre-eclampsia.

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Female

The potential value of a short self-completion questionnaire for the assessment of habitual physical activity in pregnancy.

The aim of this methodological study was to validate a newly designed self-completion questionnaire assessing various dimensions of physical activity among 100 pregnant women in Bristol, UK. For this purpose different measures obtained by self-completion questionnaire were compared with those simultaneously obtained by two established assessment methods for physical exertion. Based on the findings it was suggested that the self-completion questionnaire be slightly modified by adding questions pertaining to household activities and deleting questions which proved to be conceptually meaningless. It is concluded that in future studies this strategy will facilitate the understanding of the complex relationship between way of life and pregnancy outcome.

Activities of Daily Living

Umbilical vein administration of oxytocin for the management of retained placenta: is it effective?

In a multicenter randomized controlled trial involving 220 women with retained placenta no beneficial effects could be established of intraumbilical vein administration of 10 IU of oxytocin in 20 ml of saline solution. A reduction was not gained in the rate of manual removal of the placenta and there was no decrease in the amount of blood loss. Oxytocin only induced a minor shortening of the median time interval from administration to the spontaneous expulsion of the placenta as compared with a placebo injection. Maternal serum alpha-fetoprotein levels before and after intraumbilical vein injection did not show evidence of fetomaternal transfusion.

Adult

Determinants of preterm birth in Curaçao, Netherlands Antilles.

In order to identify risk factors for preterm birth in singletons, data from a population-based case control survey on the island of Curacao were re-analysed. Both medical and sociodemographic variables were examined. Overall, a history of previous preterm birth and severe hypertension during the index pregnancy were indicators of adverse pregnancy outcome, in terms of preterm birth. The contribution of sociodemographic factors to the risk of preterm birth is relatively low.

Abortion, Spontaneous

Is preterm delivery genetically determined?

Surprisingly, the genetics of preterm delivery have received very little attention in the literature. Possible explanations are the inability to obtain accurate information on the length of gestation in family studies and the heterogeneous nature of this disorder. In contrast to the many studies which consider the relative contribution of both genetic and environmental variance to the total variance of birthweight, few studies have examined the genetic basis of the duration of gestation in man. It is argued that both genetic and epidemiological approaches are needed to separate the effects of heredity and the environment on the duration of gestation.

Birth Weight

Birth asphyxia and obstetric care in Curaçao Netherlands Antilles.

Out of the 223 fetal and neonatal deaths that occurred on the island of Curaçao in a 2-year period (1984-1985), 35 were due to birth asphyxia (15.7%). In order to evaluate the quality of obstetric care, the circumstances surrounding each asphyxiated death were scrutinized. On the whole, patients' compliance with antenatal care was satisfactory. However, when the woman presented in labor the attending physician or midwife often lacked information on maternal antecedents and the course of pregnancy. Inadequate intrapartum surveillance together with failure to respond appropriately to abnormalities in labor constituted the principle factors which were associated with asphyxiated deaths. In addition, asphyxial conditions during labor were often preceded by inappropriate administration of oxytocic agents.

Adolescent

Conjoined twins and abdominal pregnancy.

Abdominal pregnancy is rare; conjoined twins are also rare. The diagnosis of abdominal pregnancy is easily missed and often not made until near full-term. Similarly conjoined twins are not diagnosed until late in gestation or during parturition. In this case, the diagnosis of conjoined twins and abdominal pregnancy was only made during laparotomy.

Abnormalities, Multiple

Predictors of foetal and neonatal mortality in Curaçao, Netherlands Antilles. A multivariate analysis.

In Curaçao a systematic and comprehensive investigation of numerous factors, potentially associated with an increased risk of foetal and neonatal mortality, was carried out in a 2-year period (1984-85). The inquiry was restricted to singleton births. Data on 205 women who experienced pregnancy loss were compared with those on 913 women who did not sustain foetal or neonatal loss. Data comprised information on maternal characteristics, clinical course of pregnancy and delivery, and neonatal characteristics. Of 130 factors measured, 14 were entered into a multivariate analysis. From the analysis 5 risk factors emerged as significant predictors of mortality: gestational age, birth weight, sex, foetal presentation and congenital anomalies. Factors such as social class, marital status, maternal age and parity were not associated with an increased risk of foetal and neonatal mortality in Curaçao.

Adult