A rapid method for the determination of iopanoic acid (IOP) in dog plasma utilizing a Hisep column was developed. A mobile phase of 12% methanol, 88% 0.05 M phosphate buffer pH 3.4 yielded a k' of 8.5 with no interference from proteins present in plasma. Recoveries of IOP from spiked plasma ranged from 97% to 103% at 270 mumol/L and 1.75 mmol/L respectively. Replication was +/- 2.8% at 1.75 mmol/L and +/- 6% at 21 mumol/L. A method utilizing 2,4,6-triiodobenzoic acid as internal standard was also developed for comparison.

Animals↗

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Born on the 5th of July.

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History, 20th Century↗

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Silent aspiration.

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Aged↗

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Follow-up care after an attempted suicide.

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Aftercare↗

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Health action is: more than just a health issue.

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Adolescent↗

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Sexual health: understanding sexual health.

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Economics↗

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'Xtra' contractual referrals.

This article will consider key issues of extra contractual referral (ECR) management primarily from a purchaser's perspective. What ECRs are, why their management is a vital concern for the NHS and what actions are necessary to ensure priority setting is not distorted will be briefly addressed.

Contract Services↗