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Biomedical subjects

H Hooshmand

Publications and source records attributed to H Hooshmand.

At least 19 recordsLinked to original sources
PubMed1989

The neurophysiological aspects of electrical injuries.

Neurologic and psychologic studies were done on 16 victims of alternate current electrical injuries. The patients were followed for a period of over 5 years. The findings point to a stereotyped generalized cerebral dysfunction, resulting in depression, divorce, unemployment as well as a high incidence of atypical seizures (atonic and myoclonic seizures). The EEG and CT studies were nondiagnostic. Evoked potentials revealed abnormalities in the upper cervical spinal cord and lower brain stem regions, raising the possibility that the epileptogenic focus was too deep to be recorded by standard surface EEG recording. The fact that the electrical injury patients have a high incidence of severe emotional disturbance and post-traumatic depression along with atypical seizures, in the face of nondiagnostic EEG and CT studies, may result in improper management of such patients.

Adult↗
PubMed1989

Technical and clinical aspects of topographic brain mapping.

TBM provides physiological and diagnostic information which is quite complementary to EEG, but does not replace the need for standard EEG recordings. For example, it does not show subtle morphologic abnormalities such as FIRDA, PLEDs or epileptiform discharges. Simultaneous EEG recording as well as impeccable technique are essential in proper recording of TBM, particularly as it can generate new forms of artifact. By prolonging the averaging time to over 180 seconds, and by application of flexible montages, a more accurate and cleaner record with less artifact can be obtained. Certain phenomena such as "centrifugal effect" and "comet effect" are examples of new problems generated by the advent of TBM. On the other hand, TBM can demonstrate subtle asymmetries, lateralization and localization effects more efficiently than a standard EEG. TBM is quite helpful clinically, when recording is done properly from a technical standpoint, in the diagnosis of post-traumatic syndrome and post-traumatic seizure disorder. It demonstrates subtle focal and lateralized asymmetries in cerebral hemispheric frequency bands in such patients. This information helps differentiate neurologic complications from psychiatric disorders. TBM plays a useful role in the differentiation and management of various other disorders, including depression, behavioral disturbances and dementias.

Adolescent↗
PubMed1976

Seizure disorders associated with neurosyphilis.

Sixty-eight of 282 neurosyphilitic patients (24.1%) had repetitive adult onset seizures of unknown cause. Serum and CSF FTA-ABS were more accurate diagnostic tests than the non-treponemal serologic tests. The latter tests were reactive in only 54.5% of patients. In addition to standard anticonvulsants, the patients received 20-24 million units procain penicillin G IM during a three week period. The therapeutic failure rate among these patients was 17.3% in contrast to the nonsyphilitic patients who had 21.8-38.6% failure rates. The prognosis of seizures in GPI patients was the worst regardless of the form of treatment. The use of serum and CSF FTA-ABS is recommended as a part of diagnostic evaluation of adult-onset seizure disorders. The use of large doses of penicillin seems to improve the results of treatment.

Adolescent↗
PubMed1975

Serum lactate dehydrogenase isoenzymes in neuromuscular diseases.

Serum LDH isozymes render qualitative information which may be more specific than the quantitative changes of total serum LDH and total serum CPK in neuromuscular diseases. Muscle LDH isozymes vary with age, muscle, and species. Temporal study of serum LDH isozymes in experimental neurogenic atrophy demonstrated a temporary rise of serum LDH 5. In acute and progressive neurogenic diseases, a high serum LDH 5 was noted. Isozyme patterns were normal in chronic and non-progressive diseases. In Duchenne dystrophy, serum LDH 5 was low and stayed low until the final stages of the disease. This abnormality persisted long after serum total LDH and CPK returned to normal. This may reflect the leakage of genetically abnormal isozymes from the muscles to serum. It is concluded that the serum LDH isozyme pattern is a reliable qualitative test in the diagnosis of a genetic myopathy, and in differentiating progressive from static neurogenic atrophies.

Adolescent↗