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Biomedical subjects

H Honda

Publications and source records attributed to H Honda.

At least 631 records · Page 35Linked to original sources

Selection of a rechargeable internal back-up battery for a totally implantable artificial heart.

Three kinds of rechargeable batteries, NiCd, NiMH, and Li+, were compared for the purpose of selecting the most appropriate battery for use in a Rechargeable Internal Back-up Battery (RIBB) unit for a Totally Implantable Artificial Heart. Batteries of each kind were connected in series to obtain the required driving voltage of 24 V. The NiCd and NiMH batteries were charged by a constant current of 1 C, and the Li+ batteries were charged first by a constant current of 1 C and later by a constant voltage of 28.7 V. All three types of batteries were discharged using a dummy electronic pulsatile load consuming 20 W of power. The tests showed that the Li+ batteries were capable of supplying the required energy for more than 60 minutes. The Li+ batteries had a specific energy of 121.5 Wh/kg, which was more than 3x that of the NiCd and NiMH, and an energy density of 282.5 Wh/L more than double that of the other two. In addition, the Li+ batteries recorded the least temperature rise during charging and discharging. The results of our tests conclusively showed that the Li+ battery is the best among the three for use in an RIBB from the viewpoint of energy density and temperature rise.

Electricity↗

Replacement lipomatosis of the kidney: CT features.

Replacement lipomatosis of the kidney is a severe loss of renal parenchyma with massive fat deposition associated with long-standing inflammation and calculi. We report two pathologically proven cases of total replacement lipomatosis and one partial replacement lipomatosis diagnosed by CT. The CT images demonstrated a large fat-attenuating mass with perirenal capsule surrounded by thick pararenal fascia, streaky densities in the mass, elongated collecting system, large calculi, and absence of renal parenchyma.

Aged↗

Evaluation of a PACS workstation for assessment of body CT studies.

Conventional hardcopy images from 266 body CT studies were compared with those provided at a commercially available picture archiving communication system (PACS) workstation. Unprocessed PACS images were larger but otherwise precisely duplicated hardcopy images. The PACS images were evaluated before and after application of various image processing/display features. Approximately three-quarters of the cases were depicted equally well with PACS and hardcopy, but in one quarter of the cases, diagnostic features were judged to be shown more clearly at the PACS workstation. When PACS images were viewed first, change in diagnosis after subsequent hardcopy inspection was infrequent (confidence change: 4%; different findings: 2%). Conversely, when hardcopy images were viewed first, change in diagnosis after subsequent PACS inspection was more frequent (confidence change: 19%; different findings: 8%). Specialized image manipulation available on PACS was critical for its performance. Review of cases with new findings discovered during the second inspection showed the majority of them to be clinically significant, true-positives discovered by PACS. We conclude that PACS is a useful modality for interpretation of body CT images.

Evaluation Studies as Topic↗

Renal arteriovenous malformations: CT features.

The CT and clinical features of six patients with congenital renal arteriovenous malformation (RAVM) were reviewed to determine the characteristics of this condition. The most common symptom was hematuria. The CT images were characterized by masses of vascular density located in the renal sinus and surrounding the pelvicaliceal system with or without dilated renal veins. The exact size of the RAVM and the relation to the pelvicaliceal system were well demonstrated by delayed images or drip infusion technique, whereas the bolus injection technique was essential to document the vascular nature. The potential pitfalls in diagnosis that can occur if only an infusion study is performed are discussed.

Adult↗

Intravenous leiomyomatosis of uterus: MR appearance.

We report a case with intravenous leiomyomatosis of uterus that showed characteristic appearances on MR. Magnetic resonance demonstrated a tangle of distended and folded tubular structures, well enhanced by Gd-diethylenetriamine pentaacetic acid. It was confirmed by surgery that these tubular structures reflected the vessels markedly dilated by intravascular tumor.

Adult↗

MRI of primary spleen angiosarcoma with iron accumulation.

A case of splenic angiosarcoma with siderotic nodules is reported. The tumor was hyperechoic on ultrasound and had high density on CT and very low intensity on MR. Gandy-Gamna nodules (siderotic nodules) were demonstrated histopathogically.

Hemangiosarcoma↗

MRI of primary lymphoma of the liver.

OBJECTIVE: The MR findings in two cases of primary lymphoma of the liver (PLL) are presented. MATERIALS AND METHODS: MR of two cases of primary lymphoma of the liver were reviewed and its features were estimated. RESULTS: Both cases showed a solitary large liver mass. On T1-weighted imaging the tumor was isointense in one and homogeneously hypointense to the liver parenchyma in the other. On T2-weighted imaging both tumors were homogeneously hyperintense. In one case the margin of the tumor was poorly defined, and portal branches were identified within the tumor, an unusual finding in other liver neoplasms. CONCLUSION: In patients with liver masses with homogeneous intensity on MR but without liver dysfunction and other malignancies, PLL should be included in the differential diagnosis.

Aged↗

Leiomyosarcoma of the kidney: CT and MR appearance.

A case of leiomyosarcoma of the kidney is reported here with its CT and MRI manifestations correlated to the pathologic findings. The leiomyosarcoma appeared as a well-defined multinodular mass of varying density and signal intensity on CT and MRI, respectively. The low signal-intensity regions on T2-weighted MRI exhibited delayed enhancement on CT and contained more fibrous tissues than did other sites that had more spindle-shaped muscle cells. Knowledge of the MR and CT characteristics may permit radiologists to refine the diagnosis of renal leiomyosarcoma considerably.

Female↗

Inflammatory pseudotumors of the spleen: CT and MRI findings.

OBJECTIVE: Our goal was to elucidate the CT and MRI findings of inflammatory pseudotumors of the spleen. METHODS: The CT and MRI findings of three patients with inflammatory pseudotumors of the spleen were reviewed and compared with the pathologic findings. RESULTS: On the early phase of CT, the masses were hypodense to the normal spleen, and on the delayed phase, they demonstrated delayed enhancement. On T1-weighted MR images, the masses were isointense to the normal spleen, and on T2-weighted images, the masses had heterogeneous low signal intensities. After administration of Gd-DTPA, the masses showed delayed enhancement. CONCLUSION: Inflammatory pseudotumors of the spleen were characterized by low signal intensity on T2-weighted MR images and delayed enhancement after contrast material administration on CT and MRI. The fibrous stroma may contribute to these unusual findings.

Adult↗

Computed tomographic findings of Bellini duct carcinoma of the kidney.

OBJECTIVE: To analyze CT findings of Bellini duct carcinoma, a rare variant of renal cell carcinoma. MATERIALS AND METHODS: The CT findings of five cases of Bellini duct carcinoma were reviewed and the findings were recorded. RESULTS: In all cases the affected kidneys maintained the normal outer contours. In four cases the renal masses protruded into the central sinuses. Contrast enhancement was minimal in four cases. CONCLUSION: Bellini duct carcinoma should be suspected in cases with these CT findings.

Adult↗

Efficacy of helical CT in T-staging of gastric cancer.

PURPOSE: The purpose of this study was to evaluate the performance of helical CT in preoperative T-staging in patients with gastric cancer. METHOD: A total of 71 patients with an established diagnosis of gastric cancer [75 lesions, 46 early (T1) and 29 advanced (T2 or more) cancers] were evaluated with helical CT. Helical CT was performed with 5-mm slice thickness at 5-mm/s table incrementation. Using the volumetric data by helical scanning, axial CT images (5-mm slice thickness at 5-mm intervals) and multiplanar reconstruction (MPR) images were obtained. CT findings were compared with histopathologic studies of the resected specimen. RESULTS: Sensitivity of helical CT for gastric cancer was 26% (12 of 46) for early and 100% (29 of 29) for advanced cancer. Three lesions were misdiagnosed as gastric cancer by helical CT. Histopathologically, all early gastric cancers detected by helical CT were either polypoid or elevated types or showed massive invasion of the submucosal layer. The differentiation between T1 cancer with massive submucosal invasion and advanced cancer was difficult. The differentiation between T2 and T3 cancer was possible in 73% (19 of 26) and between T1/T2 and T3/T4 (extraserosal invasion) in 83% (34 of 41). Overall T-staging was correct in 66% (27 of 41). MPR images improved the detection rate (three lesions) or increased confidence in T-staging (eight lesions) over axial CT images. CONCLUSION: When helical CT detected gastric cancer that was not a polypoid or elevated type with underlying normal-appearing gastric wall, it was either T1 cancer with massive invasion of the cancer cells into the submucosal layer or advanced cancer. However, differentiation between these two stages was difficult on CT. Diagnosis of serosal invasion was not markedly improved by helical CT. MPR images increased confidence in the staging of certain gastric cancers, such as those in locations where CT images are susceptible to partial volume averaging effects.

Adult↗

MRI of groove pancreatitis.

PURPOSE: The purpose of this work is to describe the findings on MRI in patients with groove pancreatitis, a specific form of chronic pancreatitis affecting the groove between the pancreatic head, the duodenum, and the common bile duct. METHOD: MR images, including MR cholangiopancreatography, of five patients with groove pancreatitis were reviewed. Three patients underwent pancreatoduodenectomy due to serve duodenal stenosis, and the MR findings were compared to the histologic findings. RESULTS: A sheet-like mass was demonstrated between the pancreatic head and the duodenum in all patients. The masses were hypointense relative to pancreatic parenchyma on T1-weighted images and iso- to slightly hyperintense on T2-weighted images. After administration of Gd-DTPA, the masses showed delayed enhancement. Histologically, fibrous scar tissue was detected in the groove. CONCLUSION: MR images can clearly demonstrate the fibrous tissue in the groove in groove pancreatitis, and MR cholangiopancreatography can also provide useful information.

Adult↗

Hepatic angiomyolipoma: report of changing size and internal composition on follow-up examination in two cases.

We present two cases of hepatic angiomyolipoma in which the size and internal composition of the tumor changed during the course of follow-up study. The tissue elements composing the tumor are thought to grow or regress independently during the disease's clinical course. Radiologists should be aware that hepatic angiomyolipoma can change in size and internal composition during its natural course.

Adult↗

Radiologic features of intrahepatic bile duct adenoma: a look at the surface of the liver.

We report the radiological features of intrahepatic bile duct adenoma (BDA) in three patients. BDA was shown as a small mass located in the peripheral region of the liver with each imaging modality: a hypervascular mass on angiography and a mass appearing as early nodular enhancement found disproportionately evident compared with their small size and distinct delayed or prolonged enhancement on CT. BDA should be included in the diseases to be differentiated from hypervascular hepatic tumors.

Adenoma↗

Radiologic diagnosis of adenomyomatosis of the gallbladder: comparative study among MRI, helical CT, and transabdominal US.

PURPOSE: The goal of this work was to evaluate the diagnostic accuracy of transabdominal ultrasound (US), helical CT, and MRI in the diagnosis of adenomyomatosis (ADM) of the gallbladder. METHOD: Twenty patients with surgically proven ADM were included, all of whom underwent preoperative US, helical CT with 3 mm collimation, and MRI with half-Fourier rapid acquisition with relaxation enhancement (RARE). All images were retrospectively reviewed by two radiologists, and the presence of ADM was assessed at three compartments (neck, body, and fundus) of the organ. Receiver operating characteristic analysis was performed, and sensitivity, specificity, and accuracy were calculated for each modality. RESULTS: The A z values (area under the curve) for MRI, helical CT, and US were 0.98, 0.85, and 0.72 for the Reader 1, respectively, showing no statistically significant interobserver difference in any of the three modalities. MRI showed a significantly higher A z value than helical CT or US (p < 0.1). The accuracies of MRI, helical CT, and US were 93, 75, and 66%, respectively. CONCLUSION: Among the three modalities tested, MRI with half-Fourier RARE sequence was the most accurate for diagnosing ADM.

Adenomyoma↗

Epidemiological characteristics of the incidence of hepatitis C virus (C100-3) antibodies in patients with liver diseases in the inshore area of the Yangtze River.

The Nantong area is an endemic region of hepatitis B virus (HBV) infection in the inshore area of the Yangtze River. However, no detailed data are available about hepatitis C virus (HCV) infection in this area. In this study recent reports are reviewed about the incidence of viral hepatitis and primary hepatocellular carcinoma (PHC) in China, and it is shown that the Nantong area is a high risk region for PHC. This study reports on the incidence of antibody to HCV (anti-HCV) in patients with chronic liver diseases in the Nantong area; investigated in collaboration with members of the Nantong Medical College, Jiangsu Province, the People's Republic of China. The incidence of anti-HCV (C100-3) in the Nantong area was: 0.67% (three of 451) in donor blood; 0.0% (none of 89) in patients with acute hepatitis; 2.7% (five of 186) in those with chronic hepatitis, 4.5% (two of 44) in those with liver cirrhosis; 6.3% (one of 16) in those with PHC; and 1.3% (one of 78) in patients without liver disease. The incidence of hepatitis B surface antigen in the Nantong area was: 15.7% (14 of 89) in patients with acute hepatitis; 81.2% (151 of 186) in those with chronic hepatitis; 81.8% (36 of 44) in those with liver cirrhosis; 87.5% (14 of 16) in those with PHC; and 20.5% (16 of 78) in patients without liver disease. Although the Nantong area is a high risk region for PHC, these data suggest that HCV infection is not an important aetiological factor for PHC in this area.

Adolescent↗

HCV infection and its clinical features in recipients of blood screened for HCV (C100-3) antibody.

After adoption of the anti-hepatitis C virus (C100-3) test, the incidences of definite and suspected cases of post-transfusional hepatitis (PTH) were 3.3% (7/209) and 7.2% (15/209), respectively. Four patients with definite PTH and seven patients with suspected PTH became positive for hepatitis C virus (HCV)-related antibodies or HCV-RNA after transfusion. These cases that became positive for anti-HCV or HCV-RNA showed a peak of alanine aminotransferase (ALT) more than 4 weeks after operation. Only rare cases that showed ALT peaks within 4 weeks after operation became positive for HCV-related antibodies or HCV-RNA. The peak ALT levels in cases showing positive conversion tended to be higher than those in cases showing no conversion. Judging from these results, cases of suspected PTH include those of transient liver disease attributable to surgery as well as clear cases of HCV infection. Thus new diagnostic criteria are required including data on HCV antibodies or HCV-RNA.

Alanine Transaminase↗

Incidence of hepatitis C virus (HCV) antibodies and HCV-RNA in blood donors and patients with liver diseases in the inshore area of the Yangtze River.

The Nantong area is a high risk region for primary hepatocellular carcinoma (PHC) in the inshore area of the Yangtze River. However, no detailed data are available about hepatitis C virus (HCV) infection in this area. We examined the incidences of anti-HCV and HCV-RNA in blood donors with hepatitis B surface antigen (HBsAg)- and hepatitis B core antibody (HBcAb)-negative and patients with chronic liver diseases in the Nantong area at Nantong Medical College, Jiangsu Province, the People's Republic of China. The incidences of HBV markers (HBsAg and/or HBcAb), anti-HCV (C100-3), second generation anti-HCV, HCV-RNA and any marker of HCV in the Nantong area were found to be: 0.0, 0.7, 0.4, 0.2 and 0.7% in donor bloods; 16.9, 0.0, 3.4, 15.7 and 16.9% in patients with acute hepatitis; 82.8, 2.7, 4.8, 7.5 and 10.2% in those with chronic hepatitis; 86.4, 4.5, 9.1, 4.5 and 11.4% in those with liver cirrhosis; 87.5, 6.3, 0.0, 0.0 and 6.3% in those with PHC; and 21.8, 1.3, 1.3, 0.0 and 1.3% in patients without liver diseases, respectively. Although the Nantong area is a high risk region for PHC, these data suggest that HCV infection is not an important aetiological factor for PHC in this area.

Blood Donors↗