[Boundary questions of motivation].
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Biomedical subjects
Publications and source records attributed to H Hoffmeister.
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In an exploratory study involving 818 pupils 12-16 years of age blood pressure, total serum cholesterol, and smoking behavior were studied. 38.3% of the boys (N = 154) and 47.3% of the girls (N = 143) aged 15-16 demonstrated singular or combined elevated risk variables, cigarette smoking being the most predominant risk factor. 44.5% of the pupils of this age group answered to be regular smokers. 59.8% (N = 183) of secondary school pupils stated to be regular smokers as compared to 15.7% (N = 166) of grammar school pupils. The most important socialpsychological process variables were attitude of friends towards smoking, smoking experience of friends, and social function of smoking within groups. The importance of these variables showed differences according to type of school as well as gender which should be taken into account modelling preventing programmes.
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In a comparative study, the differences between the values measured for 26 blood and serum components in both winter and summer were determined in 78 healthy subjects. Comparable conditions during the preparation of test persons, sampling, processing of specimens, and measurement were strictly observed. The term "season" is defined more precisely by meterological data. In the summer season, significantly higher values were found for leukocytes (9%), lactate dehydrogenase and MCHC (7% each), creatinine (7%, in women only), and MCH (1%) whereas significantly lower values were exhibited by aspartate aminotransferase (18%), alanine aminotransferase (14%), alkaline phosphatase (11%), glucose and packed cell volume (7% each), MCV (6%), total protein (2%), erythrocytes, albumin, sodium and chloride (1% each). These partly considerable alterations should be taken into account in the establishment of reference values and evaluation of laboratory findings (above all, when intraindividual comparison is involved). There were no significant alterations of the following parameters: hemoglobin, gamma-glutamyl transferase, urea, uric acid, creatinine (men only), bilirubin, cholesterol, total glycerol, potassium, calcium, and inorganic phosphate. In another series of experiments involving 32 test persons, the influence of different ambient temperatures during blood sampling on the above mentioned blood components was studied. Within the 18-30 degrees C range, no significant alterations were detected.
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Nutritional habits were evaluated in 31 patients with confirmed chronic calcifying pancreatitis (CCP) (n = 11, mean age 43,9 years) and chronic non-calcified pancreatitis (CP) (n = 20, mean age 44,5 years). Each patient was matched with two healthy persons of same age, sex and social class. In the patients with CCP before onset of the clinical disease the daily intake of fat (156 g versus 89 g), of carbohydrates (325 g versus 262 g, of alcohol (124 g versus 19 g) and of total calories (4110 versus 2250) was significantly higher than in the control persons. In the patients with CP likewise the daily intake of fat, alcohol and total calories (3598 versus 2069) was significantly higher than in the controls. After onset of the clinical signs of pancreatitis, the intake of nutrients was significantly reduced, mainly due to a lower intake of fat and alcohol.
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The extent and dynamics of changes by short (1 min) or prolonged (6 min) tourniquet application while obtaining venous blood samples were analysed with respect ot 33 frequently measured constituents of blood and serum. After 6-minute tourniquet application the values for red cells, haemoglobin, packed cell volume, total protein, albumen, gamma-glutamyl transferase, alkaline phosphatase, lactate dehydrogenase, creatinekinase, bilirubin, cholesterol, total glycerol and calcium increased by an average of 4-9%. One-minute tourniquet application did not have a significant effect. Levels of sodium, potassium, carbon dioxide, creatinine, uric acid, ratio of electrophoretic fractions and the MCV, MCH and MCHC indices were not affected even by 6-minute tourniquet applications. The introduction of blood sampling under standardised conditions is proposed.
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