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Biomedical subjects

H Higuchi

Publications and source records attributed to H Higuchi.

At least 307 records · Page 17Linked to original sources
PubMed1982

[The determination of 210Pb in lead (author's transl)].

Since lead contains more or less 210Pb, the selection for lead materials has to be done before construction of the low level radiation shield. In this paper, a method for determination of 210Pb is based on radioanalytical separation such as DDTC (sodium diethyl dithio carbamate) extraction followed by beta ray counting of 210Bi. Fourteen commercial lead samples and three old lead samples were analysed for 210Pb. The concentration for 210Pb in commercial samples was found to range from 0.063 to 11 Bq/g (1.7 to 300 pCi/g) and in old samples was less than 0.01 Bq/g (0.3 pCi/g). These results will be useful to the selection of shielding material. The detection limit and the time required for 210Pb determination was 0.003 Bq/g (0.1 pCi/g) and 5.5 hours, respectively.

Bismuth↗
PubMed1981

Receptor-activated and energy-dependent decrease of muscarinic cholinergic receptors in guinea-pig vas deferens.

Organ cultures of guinea-pig vasa deferentia were used for studying both the decrease in muscarinic cholinergic receptor (mAChR) concentration induced by muscarinic agonists and the simultaneous decrease in contraction to ACh. After a lag period the decrease followed first-order kinetics and was completely blocked by atropine. The decrease was dependent not only on the extent of occupation of mAChR by ACh, but was also related to the efficacy of agonists as deduced from the contractions. Moreover the amount of mAChR was not affected by other contractile agents, norepinephrine and high K+ even under conditions in which mAChR was occupied by atropine or pilocarpine. These findings indicate that the decrease in the amount of mAChR mediated by muscarinic receptors in vas deferens was due to the extent of both receptor occupation and receptor activation by agonists. Furthermore it was shown that the decrease involved energy- and temperature-dependent processes and that cyclic nucleotides did not regulate the quantitative level of mAChR.

Animals↗
PubMed1981

[A case report: Osler-Weber-Rendu disease with cerebral aneurysm, cerebral arteriovenous malformation and pulmonary arteriovenous fistula (author's transl)].

Osler-Weber-Rendu disease (hereditary hemorrhagic telangiectagia) is a rare vascular disorder which is characterized clinically by inherited telangiectasia of skin, mucous membrane and recurrent hemorrhage. However, it is not rare that various organs, for instance, lung, liver, intestine are inflicted by vascular disorder in this disease, and central nervous system is not an exception. A 60-year old man was examined for repeated epistaxis and an episode of subarachnoid hemorrhage. In this case, left middle cerebral artery aneurysm, arteriovenous malformation fed by left posterior cerebral artery and pulmonary arteriovenous fistula were revealed by angiography and computerized tomography. It is interesting that various vascular disorders were found in one case.

Arteriovenous Malformations↗
PubMed1980

[Intracranial osteochondroma -case report (author's transl)].

Intracranial osteochondroma or chondroma is rarely seen. A case of osteochondroma in the right middle fossa was presented with a review of twenty-six cases reported in Japan. A 41-year-old male was admitted to Nippon Medical School hospital with five years history of double vision. Neurological examination revealed right abducens palsy and a slight degree of ipsilateral exophthalmos. Craniogram showed a mottled calcification without definite bone destruction. EMI scan showed an irregularly shaped high density area, which was not enhanced after contrast media infusion. The bone scintigraphy employing 99mTec-MDP revealed an abnormal uptake in the right orbital region and proved to be a valuable technique for the detection of osteochondroma. The tumor was subtotally removed by a right frontotemporal craniotomy. Histologically this tumor was confirmed to be osteochondroma. The patient was discharged about one month after operation and then returned to work.

Adult↗
PubMed1980

[Gastric perforation in ventriculo-peritoneal shunt--a case report (author's transl)].

The case is a 69-year-old female who was admitted to our hospital under the diagnosis of normal pressure hydrocephalus secondary to cerebral infarction. V-P shunt was performed and postoperative course was uneventful until 7 months after operation, when she developed meningitis. Since then the level of consciousness became gradually worse down to akinetic mutism. Two years and 3 months after the operation she died of pneumonia. At autopsy peritoneal end of the shunt tube was found to have perforated the antero-inferior wall of the stomach. In this report, we discussed the mechanism of development of bowel perforation and preventive measures against this complication. As the causative factors it should be noted first that any foreign body in the peritoneal cavity is potentially able to cause bowel perforation. The second factor is the sharp tip of the peritoneal tube which perforates the bowel more easily. The third factor is the constant pressure at the same site of the bowel wall over a long period of time to cause necrosis of it. The fourth factor is the poor general condition of the patient with decreased resistance of the bowel wall against the foreign body. We therefore postulate for the prophylaxis and early diagnosis of this complication that a careful procedure with adequate tube is required at operation and a low grade fever and abdominal symptoms should not be overlooked afterward.

Aged↗
PubMed1980

[A case of thalamic germinoma with crossed aphasia in a dextral (author's transl)].

We present a rare case of thalamic germinoma with crossed aphasia in a dextral. A patient, 17-year-old righat-handed male, was admitted to Nippon Medical School Hospital with chief complaints of headache, abnormality of visual field and speech disturbance. There were pigmentations on the back of hand, foot and the perineum. Neurological examination revealed left homonymous hemianopsia, right slight degree of ptosis, left facial palsy, a mild paresis of the left upper extremity and motor aphasia. Right carotid angiography showed marked unrolling and midline shift of right anterior cerebral artery. CT scan revealed ring-like high density area in the right thalamic region, which was enhanced after constant infusion. Brain scintigraphy also showed an abnormal accumulation at the same site. The hen-egg sized tumor of 40 g. weight was almost totally removed by the right fronto-parietal craniotomy. The tumor was characterized histologically by the so-called two cell pattern with teratomatous components. As postoperative treatment local injection of adriamycine, irradiation and immunotherapy with picibanil were performed, and then left hemiparesis was markedly improved without sign of recurrence. Language evaluation was performed after operation. There were dysarthria, remarkable word amnesia, paraphasia and perseveration. Repetition was also impaired. His speech function was concluded to be a mixed type aphasia mainly composed of Broca's aphasia. The speech function of thalamus and crossed aphasia with dextrales were discussed.

Adolescent↗