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Biomedical subjects

H Heymann

Publications and source records attributed to H Heymann.

At least 55 records · Page 3Linked to original sources
PubMed1985

Nontraumatic perforations of the small intestine.

Nontraumatic perforation of the small intestine is very rarely found as a cause of acute abdominal disease. A series of 15 adult patients admitted to our hospital from 1973 to 1983 is reviewed. Underlying conditions were primary neoplasia (three patients), adhesions (three patients), intraluminal foreign bodies (two patients), metastases (two patients) and diverticulum (one patient). In four patients, the pathogenesis remained unclear (idiopathic perforations). As surgical therapy, resection and anastomosis is preferred in order to make a thorough histologic examination of the perforated bowel possible. A possible role of local drug toxicity in the pathogenesis of perforations has been discussed herein. No anastomotic leakage was observed. Four patients died (27 percent).

Adolescent↗
PubMed1985

[Hyperbaric oxygenation in burns].

Standardised third degree burn injuries were produced in guinea pigs and a standardized pseudomonas aeruginosa infection model was used. Therapy with oxygen under high pressure (OHP) was initiated for not experimentally infected burn wounds and for wounds contaminated with a constant number of bacteria from a certain pseudomonas aeruginosa strain. The healing process was documented by wound area determination, histological examination, and bacteriological evaluation. Not treated uninfected wounds showed better results than the ones that were treated with OHP. Infected burn wounds also healed better when they were not treated than the wounds in which OHP therapy was initiated with some delay. The immediate and consistent application of OHP therapy led to a significantly improved healing of burn wounds infected with pseudomonas aeruginosa.

Animals↗
PubMed1984

[Treatment of acromioclavicular dislocations with the Balser hook plate and ligament suture].

The method of operation is described, making the ligament suture safe with the hook-plate. A postoperative immobilisation is renounced by this supplying. The results of the follow-up examinations (n = 20) show no disadvantage to other operative methods. As the subjective complaints and the rate of arthrosis appear to be lower than with usual procedures of stabilisation, the supplying with the hook-plate according to Balser (additional to the ligament suture) seems to guarantee a particularly safe retention under biomechanical favourable conditions.

Acromioclavicular Joint↗
PubMed1984

[Ileus in the aged].

From 1973 to June 1982, 218 patients older than 70 years (148 women, 70 men) suffering from acute bowel obstruction were seen at our Dept. The mortality rate came up to 33%. Main causes of the ileus were incarcerated hernias and colonic obstruction (25% each). In case of an incarcerated hernia the authors emphasize early operation and colostomy in case of colonic obstruction due to tumour stenosis.

Aged↗
PubMed1983

[Internal intestinal splinting with a soluble tube for the prevention of recurrent adhesion ileus].

An absorbable, non-toxic, easy gliding, cross-linked gelatine tube has been developed to prevent and to treat chronical adhesion ileus. The tube is patterned upon the interior intestinal splinting with long tubes. By doing a small enterotomy it was possible to splint the whole intestine in pigs or endangered parts within a few minutes. The flexible gelatine tube does not kink and is melting off from the surface. It prevents the intestine from kinking and does not cause any lesions even on previously damaged intestinal walls. Possible complications seen by insertion and extraction of conventional tubes were not observed.

Animals↗
PubMed1982

[Carcinoid tumors of the gastro-intestinal-tract (author's transl)].

The prognosis of carcinoid tumors of the Gastro-Intestinal Tract (GIT) is determined by the site and size of the tumors. Carcinoid of the vermiform appendix and the rectum cause early symptoms making early diagnosis and treatment relatively easy. The 5-year-survival rate is 99% and 83% respectively. Carcinoid tumors involving the stomach and the colon with 5-year-survival rates of 52% and 53% respectively have an unfavourable prognosis. In between is the carcinoid tumor of the small intestine with a survival rate of 60%. Tumors with diameter less than 2 cm can be excised locally. Bigger tumors--as a rule--must be managed according to the principles of tumor surgery. The operative treatment of metastasis improves the prognosis especially of small intestine carcinoids. One should endeavor to remove also metastasis of carcinoid tumors of other localizations.

Apudoma↗
PubMed1981

[Animal experiments with bile peritonitis].

Contrary observations exist in the publications concerning the bile peritonitis. Therefore the effect of sterile bile in the peritoneal cavity was investigated in the white mouse. We had the following results: 1. The L.D. 50 will be obtained only by high bile concentrations. 2. The chemical bile effect is minimal on the visceral and parietal peritoneum in the early and late phase. 3. The bile peritonitis does not get infected in case of the intact gastrointestinal and biliary tract. There does not exist a so-called passing through peritonitis even with big bile quantities. 4. A reduction of the peritoneal adhesions arises by bile influence and by weak adhesion stimuli.

Animals↗
PubMed1979

Isolation of atypical lipopolysaccharides from purified cell walls of Pseudomonas cepacia.

Wall fragments were prepared from two strains of Pseudomonas cepacia and from P. aeruginosa, and their contents of readily extractable lipid, pronase-digestible protein and lipopolysaccharide were measured. Lipopolysaccharide extracted from P. cepacia, although biologically active, contained no detectable 2-keto-3-deoxyoctonic acid, but contained phosphate, rhamnose, glucose, heptose and hexosamine in concentrations comparable to those found in P. aeruginosa.

Cell Wall↗
PubMed1979

Fourteen-year survival of Pseudomonas cepacia in a salts solution preserved with benzalkonium chloride.

A strain of Pseudomonas cepacia that survived for 14 years (1963 to 1977) as a contaminant in an inorganic salt solution which contained commercial 0.05% benzalkonium chloride (CBC) as an antimicrobial preservative, was compared to a recent clinical isolate of P. cepacia. Ammonium acetate was present in the concentrated stock CBC solution, and served as a carbon and nitrogen source for growth when carried over into the salts solution with the CBC. The isolate's resistance to pure benzalkonium chloride was increased step-wise to a concentration of 16%. Plate counts showed 4 x 10(3) colony-forming units per ml in the salts solution. Comparison of growth rates, mouse virulence, antibiotics resistance spectra, and substrate requirements disclosed no differences between the contaminant and a recently isolated clinical strain of P. cepacia. The results indicate that it is critical that pharmaceutical solutions containing benzalkonium chloride as an antimicrobial preservative be formulated without extraneous carbon and nitrogen sources or be preserved with additional antimicrobial agents.

Animals↗