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Biomedical subjects

H Henning

Publications and source records attributed to H Henning.

At least 91 records · Page 5Linked to original sources
PubMed1982

[Laparoscopic aspect and clinical relevance of cholangiofibromas].

In a current series of 1160 laparoscopies in 38 cases (3.2%) we found cholangiofibromas. The picture of single, sporadic and multiple cholangiofibromas as well as cholangiofibromatosis is both described and documented by laparoscopic photography. Clinically it seems remarkable that only patients with alcohol- or drug-induced liver injury showed such alterations. The prevalence of cholangiofibromas in toxic liver damage suggests that we are here not dealing with embryonal aberrations (hamartomas) but apparently with cellular inductive phenomena.

Adenoma, Bile Duct↗
PubMed1982

[The risk of virus transmission and morbidity in sexual partners of HBeAg positive patients with chronic liver disease (author's transl)].

Sexual partners of 50 HBeAg positive patients suffering from chronic HBV-induced hepatitis were investigated for signs of HBV-transmission or morbidity. 80% of the partners have been infected. 90% of these developed immunity against HBV; 10% acquired an acute or chronic hepatitis B. We were unable to establish any predominant criteria favoring the infection. Sexual activity, in particular, in our opinion is not of paramount significance.

Adolescent↗
PubMed1979

Effects of morphine on left ventricular dimensions and function in patients with previous myocardial infarction.

To assess the effects of morphine sulfate on left ventricular function and dimensions we administered 15 mg of this agent to 11 stable patients with previous transmural myocardial infarction. All studies were carried out in the supine position. Before morphine administration an echocardiogram was obtained, and this procedure was repeated at 15, 30, 60, 120, and 240 min after morphine. Heart rate decreased from a control value of 69 +/- 4 to 62 +/- 5 beats/min 2 h after morphine (p less than 0.01, analysis of variance); this slower heart rate persisted for 4 h after morphine. Serial measurements of blood pressure, echocardiographic ejection fraction, percent of fractional shortening, and mean normalized velocity of circumferential fiber shortening also showed no significant alterations after morphine. We conclude that in stable patients with chronic ischemic heart disease studied in the supine position, 1) morphine exerts no effect on left ventricular dimensions, an observation which does not support the concept that this agent acts in humans by producing a 'pharmacologic phlebotomy'; and 2) morphine does not alter left ventricular function at rest. Whether different results will be found in patients with increased sympathetic activity, such as occurs in the setting of an acute myocardial infarction or during an episode of acute pulmonary edema, remains to be investigated.

Adult↗
PubMed1979

[Chronic persistent hepatitis. Histological and clinical study of different forms of the course of CPH].

Among 4903 liver biopsies were found 96 cases (241 biopsies) of non-active hepatitis persisting for longer than one year (up to 12 years). Three forms of the course of chronic persistent hepatitis could be delimited in morphological terms taking into account clinical laparoscopic and clinical chemical data. The type Ia presents the picture of a largely subsided, lobular accentuated acute virus hepatitis. The type Ib corresponds to a chronic inflammation with emphasis on the portal system without destruction of the limiting plate, without fibrosis and with only slight intralobular involvement. The type Ic is characterized by a portal and slight septal fibrosis with round-cell infiltrates and a slight facultative periportally active inflammation as well as a moderate intralobular mesenchyme reaction. The typing permits a clear subdivision and a differentiated prognosis: 10% of the cases of type Ic pass into an active chronic hepatitis of the type IIa.

Adult↗
PubMed1979

[Spontaneous and DL-penicillamine-induced renal copper excretion in liver diseases (author's transl)].

The levels of cupriuresis before and after DL-Penicillamine have been investigated in 168 cases. The mean copper excretion before Penicillamine in chronic activ liver disease, chronic persistant hepatitis, cirrhosis and in transitional cases of aggressiv chronic hepatitis and primary biliary cirrhosis ranged from 29 gamma to 48 gamma/24 hr.; however, in some cases the daily copper excretion exceeds 100 gamma, as well in subjects with liver disease as in normals too. After ingesting 900 mg DL-Penicillamine the mean values of cupriuresis ranged from 500 gamma to 600 gamma/24 hr. Abnormal results were found in about 15% of those subjects with liver diseases; in only two of 20 cases with hypercupruria after Penicillamine Wilson's Disease was established.

Copper↗
PubMed1979

[Improvement of fixation by early Fadenoperation (clinical and experimental observations) (author's transl)].

17 children aged 6 months to 2 1/2 years with strabismus convergence, amblyopia and overconvergence were treated with Fadenoperation on the medial rectus of the deviating eye, after therapy with occlusion had not been tolerated. In all cases tolerance of the occlusion had been achieved, central fixation in 15, unrestricted abduction in 9 children. The period of observation ranged from 18 to 24 months. Repeated controls after Fadenoperation on infantile rabbit's eyes and echografic measurements on 6 patients have stated that there is no danger of a restriction in the bulbus growth. As late retinal complication following Fadenoperation cannot be excluded, a serious indication is recommended.

Age Factors↗
PubMed1978

Inferior myocardial infarction as a cause of asymmetric septal hypertrophy. An echocardiographic study.

The diastolic thickness of the septum and posterior left ventricular wall were measured with M mode echocardiography in 68 patients 2 or more months after a single transmural myocardial infarction. In 42 patients with inferior wall infarction, the septal thickness of 12.4 +/- 0.6 mm (mean +/- standard error of the mean) was larger than the mean measurement in 26 patients with anterior wall infarction (9.6 +/- 0.6 mm, P less than 0.01). Twenty-five of these 42 patients (59 percent) had increased septal thickness (greater than 11 mm), including 12 (48 percent) who had hypertension and 11 (26 percent) who had decreased posterior wall thickness. The ratio of septal to posterior wall thickness was greater in the patients with inferior infarction than in those with anterior infarction (1.36 +/- 0.06 versus 0.89 +/- 0.06, P less than 0.001). This ratio exceeded 1.3 in 22 patients with an inferior infarction (52 percent) but was increased in only 1 patient with an anterior infarction. Hypertension did not predict the presence or absence of an abnormal ratio. Increased septal thickness on echocardiography may occur after interior infarction and result in an abnormal septal to posterior wall thickness ratio that meets current echocardiographic criteria for asymmetric septal hypertrophy.

Adult↗
PubMed1978

Right ventricular ejection fraction in patients with acute anterior and inferior myocardial infarction assessed by radionuclide angiography.

We measured right and left ventricular ejection fracttion (EF) from high frequency time-activity curves obtained during the initial passage of an intravenous bolus of 99mTc (Sn) pyrophosphate. In 22 normal controls right ventricular EF averaged 0.52 +/- 0.04 (SD). In 24 acute anterior or lateral infarction patients right ventricular EF was normal (0.56 +/- 0.10), while left ventricular EF was reduced (0.45 +/- 0.10, P less than 0.001 vs controls). In 19 acute inferior infarction patients left ventricular EF also was depressed (0.51 +/- 0.09, P less than 0.001 vs controls). Among 7 of 19 inferior infarction patients with right ventricular by scintigraphy, right ventricular EF was reduced (0.39 +/- 0.05; P less than 0.001 vs normals; P less than 0.01 vs inferior infarction patients without right ventricular involvement). In the latter group right ventricular EF averaged 0.51 +/- 0.10 (NS vs normals). We conclude 1) a single injection of 99mTc (Sn) pyrophosphate can identify right and left ventricular dysfunction and infarct location in acute myocardial infarction, 2) right ventricular EF is well-preserved except when inferior infarction involves the right ventricle.

Acute Disease↗
PubMed1978

Variability, reproducibility, and applications of precordial ST-segment mapping following acute myocardial infarction.

In 58 patients with uncomplicated acute anterior myocardial infarction, a mean decline in the sum of ST segments (sigmaST) of 34% was observed when comparing sigmaST values recorded at 3-6 hours with those recorded at 6-9 hours after the onset of symptoms (P less than 0.05). The mean absolute difference between 19 paired readings 1-2 hours apart was 2.9 +/- 3.0 mm and between 29 readings 2-4 hours apart 3.0 +/- 3.0 mm. However, the mean absolute difference between 38 paired readings 4-8 hours apart was 12.2 +/- 11.8 mm with a wide range of differences. Left ventricular failure and pericarditis were also associated with significantly higher sigmaST values. We conclude that there is a complex relationship between ST-segment elevation and a number of clinical factors during the first 48 hours after infarction. Nevertheless, precordial mapping remains a useful method for the evaluation of short-term (less than 4 hours) therapeutic interventions, if other relevant variables are unaltered and if carefully matched control groups are employed.

Acute Disease↗
PubMed1977

[The perioperative myocardial infarct after aortocoronary bypass].

Two sets of criteria are developed for the diagnosis of perioperative myocardial infarction: 1) new, persistent Q waves and either an elevated 48-hour MB-CPK area or a positive pyrophosphate scan, 2) severe ischemic ST-T wave changes and both elevated MB-CPK area and a positive scan.

Coronary Artery Bypass↗
PubMed1977

Intravenous myocardial imaging performed serially early and late after acute myocardial infarction.

The accuracy and sensitivity of myocardial imaging using intravenous Rb-81 in delineating the extent and subsequent changes in regional myocardial perfusion abnormalities were examined serially in 12 patients one to 510 days after an acute myocardial infaraction. Definite regions of decreased Rb-81 uptake were noted in 10 patients with transmural infarction. There was excellent correlation between the site of perfusion abnormalities, the electrocardiographic infarct location and the region of segmental wall motion disorders. Follow-up studies revealed in 8 of 11 patients a decrease in the extent of the perfusion defect, which was associated with an improvement in the extent and/or severity of regional wall motion disorders. Conversly, wall motion abnormalities did not change in the remaining three patients in whom perfusion abnormalities persisted unchanged. We conclude that intravenous myocardial imaging permits visualization of myocardial perfusion abnormalities early after acute myocardial infaraction. Serial imaging allows detection of changes in the extent of perfusion abnormalities, and, thus, might provide useful information with respect to the patient's prognosis and the effects of therapeutic interventions.

Aged↗