Biomedical subjects
Publications and source records attributed to H Heise.
The significance of varicocele is presented in terms of its frequency and its role in causing impairment of fertility. In this context the problems of subclinical varicocele and idiopathic sterility without detectable varicocele are dealt with. Interesting views on these questions from the literature are presented.
69 years after the introduction of x-ray examination of the seminal duct, the indication and contraindication are reviewed according to current interdisciplinary aspects, basing on 31 cases studied over a period of two years. The procedure followed in the roentgenological visualization of carcinoma of the prostate is generally recognized, whereas controversial opinions are held with regard to patients with occlusive azoospermia. The possibility of lesions and damage caused by some contrast media is an established fact. Differences in the lumen of the ductus epididymidis prevented complete visualization of the epididymis when using the previous, highly concentrated, sticky contrast media which were insoluble in water. These drawbacks have been eliminated by Amipaque. Today epididymograms are no longer considered necessary, although there are exceptions. Experience and a sophisticated technique are mandatory. If refertilization is envisaged, it is permissible during operation only to effect a descending x-ray for the purpose of clarifying the outflow conditions.
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Irritant dermatosis is a non-specific reactive change on the skin. In most cases it represents the summated effects induced by various agents. Not only the shortened recovery phases of the skin but also a dispositional factor are important. Such changes, which are relatively common in some vocations but are usually only slight, cannot, as a rule, be regarded as signs of illness. Nevertheless, attention should be drawn to the necessity of intensive skin care and observation of the recovery phases because the frequency of irritant dermatosis can increase with increasing length of employment.
Basing on the determination of ID50 and IT50 after Kligman and Wooding but involving our own modification, the primarily irritating effect of certain industrial substances on experimental animals' and humans' skin was comparatively evaluated. Mutual experimental studies have been carried out in Dermatological Clinics in Leipzig and Rostock and Dermatological Clinic at the Medical Academy of Lódź. The results were found to be generally consistent in humans and animals. Extension of international cooperation and information and results on the determination of industrial substances adverse effects seem to be necessary.
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In eight andrological centres more than 2,000 childless married men were examined catamnestically. Fertility was compared with the findings of the routine spermatograms. Conception rate is reduced significantly if sperm density is below 10 million, in motility of spermatozoa under 50% and in ejaculates with less than 60% normal-shaped spermatozoa. However, lower values of spermatozoa must not be compared with absolute infertility.
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The presence of gonorrhoea was verified by culturing in 30.3 per cent of 119 patients in whom acute adnexitis had been confirmed by laparoscopy, gonorrhoeal findings being independent of types of inflammation.--Cervical, urethral, and abdominal cultures were prepared from various materials at one and the same time. Positive responses were recorded from them in one third of the cases of gonorrhoea. Three patients exhibited positive reactions only from abdominal cultures.--Additional aerobic and anaerobic pathogens were recorded from abdominal samples in 16 of 29 cases. Their occurrence should be taken into consideration in the treatment of female gonorrhoea with concomitant adnexitis.--A recommendation is made to the effect that abdominal gonorrhoeal cultures should be prepared in all cases of laparoscopy or laparotomy for acute adnexitis. Highest rates of detection can be expected, in that context, from tubal tissue cultures.--An approach is described by which to prepare gonorrhoeal cultures with no transport medium for conditions under which hospital and gonorrhoea laboratory are not located on one and the same premises.
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One hundred ninety-one cases of unilateral noninvasive breast carcinoma were studied with regard to the development of subsequent cancers in the contralateral breast. The majority of patients were treated by mastectomy and have been followed for an average of nine years. Their overall survival did not differ significantly from that of age-specific population survival figures for U. S. women. Among all cases, 13 or 6.8% subsequently developed contralateral carcinoma; 3.1% of these contralateral tumors were invasive. The authors found only one histological type, namely lobular carcinoma in-situ for which the development of subsequent contralateral carcinomas was statistically significant. Seven of the 68 women with this type developed second breast cancers (10.3%; 4.4% of these were invasive). These data suggest that the occurrence of clinically apparent subsequent cancers developing in the opposite breast following the diagnosis of in-situ carcinoma is relatively small.