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Biomedical subjects

H Hedelin

Publications and source records attributed to H Hedelin.

At least 109 records · Page 6Linked to original sources

Abdominal trauma in persons older than 60 years.

Abdominal trauma occurring in persons older than 60 years over a 30-year period (1950-79) in a well defined region of Sweden was reviewed. The 177 patients comprised 12.5% of the total with abdominal trauma during that period. Road traffic accidents were the main cause of trauma (48% of cases). The incidence of motor-car accidents rose sharply during the first two decades of the study. Injuries to the liver and bile ducts and multiple intra-abdominal injuries were more common in the elderly than in younger patients, but injury to the abdominal wall was less common. A tendency towards more severe injuries and multiple trauma with extra-abdominal involvement emerged during the study period. The mortality rate was 27.6% in the patients older than 60, but 9.1% in the overall patient series with abdominal trauma. One-third of all the deaths among the older patients were directly due to the abdominal trauma. One consequence of the increasing numbers of old people in the general population is probably that more and more cases of abdominal trauma will be seen in the higher age groups.

Abdominal Injuries↗

Abdominal trauma during thirty years: analysis of a large case series.

Studies have been made in 1407 patients of the causes, the organs involved and the outcome of injury to the abdomen in patients needing admission to hospital in an area of Southern Sweden, between 1950 and the end of 1979. The proportion of female patients and those aged over 60 increased significantly. The seasonal distribution of the injuries showed significant change, with a drop in the initially high frequency sustained during the summer months. Penetrating injuries were rare, but increased in the 1970s. Road traffic accidents as the cause of abdominal injuries rose to a maximum of 56 per cent in the late 1960s. The numbers of injured organs and the frequency of other associated injuries rose gradually until the mid-1970s, after which there was a slight decrease. The spleen, liver and large blood vessels were the organs which were increasingly often injured. The annual incidence of various visceral injuries per 100 000 population was calculated. The number of patients with a delay of at least 24 hours before operation fell significantly and there was a tendency to shorter hospital stay. The mortality curve showed a peak in the late 1960s.

Abdominal Injuries↗

Focal prostatic granulomas. A sequel to transurethral resection.

Clinical and histologic findings in 6 cases of prostatic granuloma following transurethral prostatic resection are described. The repeat operations were performed 1 week to 14 months after the initial resection because of severe micturition urgency, voiding difficulty or persistent haematuria. Bacteriuria did not seem to be of aetiologic importance for the granulomas. In all cases the granulomas contained areas of fibrinoid necrosis, and in three cases the granulomas were surrounded by eosinophilic infiltrates. The condition is not widely recognized by pathologists, which was illustrated by the initial diagnosis of specific inflammation consistent with tuberculosis in three patients. Though the disorder seems to be self-limiting, its association with persistent haematuria after transurethral prostatic resection is noteworthy.

Aged↗

Intestinal trauma, Analysis of 101 cases.

Intestinal injuries sustained by 101 Swedish patients during the period 1950-1979 are reviewed. The abdominal trauma was blunt in 78 cases and penetrating in 23. Small-bowel and mesenteric, but not large-bowel, injuries showed increasing frequency. This was associated with rising numbers of motorcar accidents. Injuries to other abdominal organs were found in 56 of the 101 patients, particularly in those with mesenteric or large-bowel trauma. Clear physical signs of intra-abdominal injury led to rapid surgical exploration in most cases, but some operations were performed after relatively long observation. Most injuries, including those in the colon, were treated with primary repair or resection. Decompressive colostomy or exteriorization were rarely performed. Deaths were mainly caused by other factors than the type of operation. The mortality rate (35%) was constant.

Adolescent↗

Upper gastrointestinal trauma. Analysis of 45 cases of gastric, duodenal or pancreatic injury.

Injuries to the upper gastrointestinal tract occurring over a 30-year period in a geographically well defined region were analyzed. The incidence was low in comparison with other abdominal injuries, but duodenal and pancreatic injuries were increasingly common in the study's last decade. The stomach injuries were mainly caused by penetrating trauma. The duodenal and pancreatic injuries most commonly resulted from road-traffic accidents. Two duodenal injuries were overlooked at the initial exploration, in which the duodenum was incompletely exposed. Anastomotic insufficiency occurred in one of the three patients who underwent duodenal resection. Most of the pancreatic injuries were contusions that could be managed with drainage. The pancreas was severely damaged in five patients, all of whom had multiple intra-abdominal injuries. Three of the five patients died before or during operation.

Adult↗

The relevance of urinary sampling methods in patients with indwelling Foley catheters.

The relevance of different urinary sampling methods in male patients with indwelling catheters was studied. There was good agreement between the bacterial strains cultured from urine sampled at the catheter end compared to samples obtained by catheter puncture. However, one-quarter of the samples obtained by the catheter did not show complete agreement with the bladder aspiration samples. It is concluded that, in patients with an indwelling catheter, urinary sampling by the catheter does not always provide relevant information about the bacterial strains present and bladder aspiration is advised.

Aged↗

Blunt renal trauma. Changes in aetiology, Diagnostic procedure, treatment and complications over thirty years.

In a rural area with a relatively stable population, 216 persons were hospitalized for blunt renal trauma over a 30-year period (1946-75). In the final 10 years the frequency of such trauma increased, as also did the proportions of females and younger patients (11-30 years old). In the final 5 years the overall incidence was 6.2 cases per 100 000 inhabitants and year. Motor traffic accidents were increasingly the cause of blunt renal trauma. Injuries from compression showed a stable frequency. Renal trauma attributed to blows varied with the incidence of accidents involving horses and sports. Treatment was mainly conservative, except in major injuries. Emergency excretory urography was rarely used during the first 10 years of the study, but thereafter with increasing frequency. Early complications were seen only during the first 20 years of the study.

Adolescent↗

Bladder cancer associated with hypercalcaemia. A case report.

Hypercalcaemia associated with bladder cancer is rarely encountered. The case history of a male patient, 75 years old, with a large, deeply infiltrating squamous cell bladder carcinoma (T4a), hypercalcaemia (3.5 mmol/l), low parathormone level and no sign of skeletal metastases is presented. A review of earlier reported cases of bladder cancer associated with hypercalcaemia is discussed.

Aged↗

Traumatic splenic rupture during 30 years. An analysis of 88 cases with special attention to delayed rupture.

Eighty-eight cases of splenic rupture in non-penetrating abdominal injury are analysed. An increasing frequency was seen during the 30-year period studied (1946--1975). Teenagers and young adults were the most affected age groups. A rising incidence of traffic accidents amd multiple iinjuries was noted. Mortality was 21%. All patients with an isolated splenic rupture survived. The complication rate was low. The high incidence of delayed splenic rupture in earlier reports seems to be more a refleciton of the diagnostic diffulties than an actual delayed rupture. We have put the splenic ruptures into minor immediate, major immediate, and delayed. Minor splenic rupture was seen in 20% of patients undergoing operation, major in 75%, and delayed in only 5%. Three of our patients were operated on with splenorrhaphy with an uneventful postoperative course. In minor splenic ruptures, especially in young patients, splenorrhaphy could be a possible way of treatment but more controlled studies are needed before firm recommendations can be made.

Accidents, Traffic↗

Long-time follow-up of patients with conservatively treated blunt renal injuries.

A long-time follow-up of 43 patients with minor or intermediate degree blunt renal injuries is presented. A low incidence of complications, including hypertonia, calculi, and infections, was noted, but in three patients, the function of the injured kidney was affected, and two of these also had structural abnormalities as demonstrated by urography. It is recommended that the follow-up of patients with blunt renal injuries should include both urography and renography.

Adolescent↗

Changes in serum copper and serum ceruloplasmin concentration induced by surgical trauma.

Serum ceruloplasmin and copper concentration has been followed for 5 days after surgical trauma. Initially, serum ceruloplasmin concentration (non-significantly) and the serum copper concentration (significantly) decreased. The decrease was followed by an (significant) increase from day 3 postoperatively. The increase was more pronounced for the serum ceruloplasmin concentration. This suggests that a ceruloplasmin poorer in copper was produced postopertively.

Aged↗

Penetrating abdominal trauma. A comparison of the development during 30 years between a rural and an urban area.

The development of penetrating abdominal injuries during 30 years has been compared between a rural and an urban area. There was an increase in number of injured patients but the causes of injury did not change. In the urban area stab wounds, assaults, and injury combined with alcohol intoxication were significantly more frequent than in the rural, where gunshot wounds dominated. Indications for laparotomy and therapeutic management did not differ. There were minor but statistically insignificant differences in complications and mortality. Although the material is small exteriorization must be recommended as the method of choice in penetrating civilian colon injuries as it is in war injuries.

Abdominal Injuries↗